Sabeena Ahmed, Mohammad Mahbubul Karim, Allen G. Ross, Mohammad Hossain et al.
Ivermectin, a US Food and Drug Administration-approved anti-parasitic agent, was found to inhibit severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) replication in vitro. A randomized, double-blind, placebo-controlled trial was conducted to determine the rapidity of viral clearance and saf...
Carine Claeys, Khalequ Zaman, Ghassan Dbaibo, Ping Li et al.
Background Despite the importance of vaccinating children younger than 5 years, few studies evaluating vaccine prevention of influenza have been reported in this age group. We evaluated efficacy of an inactivated quadrivalent influenza vaccine (IIV4) in children aged 6-35 months. Methods In this pha...
Khalequ Zaman, Susanne Dudman, Kathrine Stene‐Johansen, Firdausi Qadri et al.
INTRODUCTION: Hepatitis E virus (HEV) is a leading cause of acute viral hepatitis in the developing world and is a public health problem, in particular among pregnant women, where it may lead to severe or fatal complications. A recombinant HEV vaccine, 239 (Hecolin; Xiamen Innovax Biotech, Xiamen, C...
Asma Binte Aziz, Rubhana Raqib, Wasif Ali Khan, Mahbubur Rahman et al.
Low- and middle-income countries (LMICs) face many challenges in controlling COVID-19. Healthcare resources are limited and so are ICU beds. RT-PCR testing is conducted on a limited scale and treatment options are few. There is no vaccine. Therefore, what low-cost solutions remain for the prevention...
Birkneh Tilahun Tadesse, Farhana Khanam, Faisal Ahmmed, Justin Im et al.
BACKGROUND: Typhoid fever contributes to approximately 135 000 deaths annually. Achievable improvements in household water, sanitation, and hygiene (WASH) combined with vaccination using typhoid conjugate vaccines (TCVs) may be an effective preventive strategy. However, little is known about how imp...
Miah Md. Akiful Haque, Yasmin Jahan, Zara Khair, Michiko Moriyama et al.
Chronic diseases, including non-communicable diseases (NCDs), have arisen as a severe threat to health and socio-economic growth. Telemedicine can provide both the highest level of patient satisfaction and the lowest risk of infection during a pandemic. The factors associated with its usage and pati...
Joakim Øverbø, Asma Binte Aziz, Khalequ Zaman, John D Clemens et al.
BACKGROUND: Hepatitis E virus (HEV) is a major cause of acute viral hepatitis worldwide and it contributes to considerable maternal and neonatal mortality and morbidity in many low-income countries like Bangladesh. A three-dose regimen of a vaccine against HEV (HEV 239) has shown promising results i...
Khalequ Zaman, Cathinka Halle Julin, Asma Binte Aziz, Kathrine Stene‐Johansen et al.
BACKGROUND: Hepatitis E virus (HEV) leads to high mortality in pregnant women in low-income countries. We aimed to evaluate the safety of a HEV vaccine and its effectiveness in preventing hepatitis E during pregnancy. METHODS: In this phase 4, double-blind, cluster-randomised trial, 67 villages in M...
Asma Binte Aziz, Susanne Dudman, Cathinka Halle Julin, Faisal Ahmmed et al.
BACKGROUND: Vaccination constitutes an attractive control measure for hepatitis E virus (HEV), a major cause of maternal and perinatal mortality globally. Analysis of pregnant participants in an effectiveness trial of the HEV vaccine HEV239 showed possible HEV239-associated fetal losses. We aimed to...
Joakim Øverbø, Asma Binte Aziz, Khalequ Zaman, Cathinka Halle et al.
Hepatitis E virus (HEV) is the most common cause of acute viral hepatitis worldwide. In many low-income countries it causes large outbreaks and disproportionally affects pregnant women and their offspring. Surveillance studies to find effective preventive interventions are needed but are hampered by...
Justin Im, Farhana Khanam, Faisal Ahmmed, Deok Ryun Kim et al.
Modest improvements in household water, sanitation, and hygiene (WASH) and typhoid vaccination can reduce typhoid risk in endemic settings. However, empiric evaluation of their combined impact is lacking. A total of 62,756 persons residing in 80 clusters in a Kolkata slum were allocated randomly 1:1...
Daniel E Velasquez-Portocarrero, Xiaoqian Wang, Margaret M. Cortese, Cynthia J. Snider et al.
Background A head-to-head comparison of the most widely used oral rotavirus vaccines has not previously been done, particularly in a high child mortality setting. We therefore aimed to compare the immunogenicity of RotaTeq (Merck, Kenilworth, NJ, USA) and Rotarix (GlaxoSmithKline, Rixensart, Belgium...
Asma Binte Aziz, Mohammad Ali, Ahsan-ul Habib Basunia, Mohammad Yunus et al.
BACKGROUND Rotavirus is one of the causes of severe diarrhea and death in young children. To control the disease, safe and effective vaccines are being used in several countries. We assessed the impact of vaccination on the risk factors for acute rotavirus diarrhea (ARD) in Bangladesh. METHODS We us...
Vibhu Kanchan, Khalequ Zaman, Asma Binte Aziz, Farzana Zaman et al.
: HSRV was found to be generally well-tolerated in both adults and infants and immunogenic in infants.
Asma Binte Aziz, Joakim Øverbø, Susanne Dudman, Cathinka Halle et al.
HEV is the most common cause of acute hepatitis globally. This review summarizes the latest knowledge on the epidemiology, clinical characteristics, testing, and treatment of HEV infection. We also focused on Bangladesh to highlight the distinct challenges and the possible remedies. In low-income se...
Asma Binte Aziz, Harish Verma, Visalakshi Jeyaseelan, Mohammad Yunus et al.
BACKGROUND: The polio eradication endgame called for the removal of trivalent oral poliovirus vaccine (OPV) and introduction of bivalent (types 1 and 3) OPV and inactivated poliovirus vaccine (IPV). However, supply shortages have delayed IPV administration to tens of millions of infants, and immunog...
Khalequ Zaman, Stéphanie Kovacs, Kristin VanderEnde, Asma Binte Aziz et al.
Background: After global oral poliovirus vaccine (OPV) cessation, the Strategic Advisory Group of Experts on Immunization (SAGE) currently recommends a two-dose schedule of inactivated poliovirus vaccine (IPV) beginning ≥14-weeks of age to achieve at least 90% immune response. We aimed to compare th...
Khalequz Zaman, Mohammad Yunus, Asma Binte Aziz, Jodi Feser et al.
INTRODUCTION: Japanese encephalitis (JE) virus is one of the leading causes of viral encephalitis across temperate and tropical zones of Asia. The live attenuated SA 14-14-2 JE vaccine (CD-JEV) is one of three vaccines prequalified by the World Health Organization (WHO) to prevent JE. WHO currently ...
Md Taufiqul Islam, Justin Im, Faisal Ahmmed, Deok Ryun Kim et al.
Abstract Background Global cholera control efforts rely heavily on effective water, sanitation, and hygiene (WASH) interventions in cholera-endemic settings. Methods Using data from a large, randomized controlled trial of oral cholera vaccine conducted in Kolkata, India, we evaluated whether natural...
Birkneh Tilahun Tadesse, Farhana Khanam, Faisal Ahmmed, Xinxue Liu et al.
BACKGROUND: Typhoid fever, or enteric fever, is a highly fatal infectious disease that affects over 9 million people worldwide each year, resulting in more than 110,000 deaths. Reduction in the burden of typhoid in low-income countries is crucial for public health and requires the implementation of ...