Armand Van Deun, Aung Kya Jai Maug, Md Abdul Hamid Salim, Pankaj Das et al.
RATIONALE: Based on expert opinion, the global guidelines for management of multidrug-resistant tuberculosis impose lengthy and often poorly tolerated treatments. OBJECTIVES: This observational study evaluates the effectiveness of standardized regimens for patients with proven multidrug-resistant tu...
Armand Van Deun, Aung Kya Jai Maug, Arman Hossain, Mourad Gumusboga et al.
SETTING: Damien Foundation Project, Bangladesh. OBJECTIVE: To evaluate sputum smear fluorescein diacetate (FDA) vital staining to predict culture-defined failure and rifampicin (RMP) resistance. DESIGN: A retrospective, operational study. RESULTS: A total of 1633 episodes of auramine smear-defined l...
Armand Van Deun, Aung Kya Jai Maug, E Cooreman, M A Hossain et al.
SETTING: A non-governmental organisation (NGO) supported tuberculosis control programme in Bangladesh with good smear microscopy. OBJECTIVE: To verify whether bleach sedimentation method increases the sensitivity of sputum smear microscopy for acid-fast bacilli (AFB), and if so, how. DESIGN: Duplica...
Aung Kya Jai Maug, M A Hossain, Mourad Gumusboga, Tom Decroo et al.
OBJECTIVE: To compare the occurrence of unfavourable treatment and safety outcomes of double-dose rifampicin (RMP; 20 mg/kg/d, intervention) with standard dose (10 mg/kg/d, control) in a first-line tuberculosis (TB) treatment regimen for smear-positive TB patients in Bangladesh. DESIGN: This was a r...
C. Ruth Butlin, David Pahan, Aung Kya Jai Maug, Stephen G Withington et al.
Introduction: Duration of leprosy treatment remains long and difficult to complete in resource poor areas. Studies suggest that shortening duration of therapy for MB patients to 6 months may be possible. Methods: New MB patients in 2005 in two NGO projects in Bangladesh were treated with 6 months WH...
Armand Van Deun, Tom Decroo, Aung Kya Jai Maug, M. Anwar Hossain et al.
BACKGROUND: Meta-analyses on impact of isoniazid-resistant tuberculosis informed the World Health Organization recommendation of a levofloxacin-strengthened rifampicin-based regimen. We estimated the effect of initial rifampicin resistance (Rr) and/or isoniazid resistance (Hr) on treatment failure o...
Mohammad Khaja Mafij Uddin, Moshtaq Ahmed, Mohammad Riazul Islam, Arfatur Rahman et al.
Tuberculosis (TB) remains a major public health problem worldwide including in Bangladesh. Molecular epidemiological tools provide genotyping profiles of Mycobacterium tuberculosis (M. tuberculosis) strains that can give insight into the transmission of TB in a specific region. The objective of the ...
Tom Decroo, Aung Kya Jai Maug, M. Anwar Hossain, Cécile Uwizeye et al.
BACKGROUND: Since a meta-analysis showed little or no effect of second-line injectables on treatment success, and using injectables may induce ototoxicity, injectable-free rifampicin-resistant tuberculosis (RR-TB) treatment regimens are recommended. However, acquired resistance preventing activity w...
Philipp du Cros, Jane Greig, J.-W. C. Alffenaar, Gail Brenda Cross et al.
BACKGROUND: The value, speed of completion and robustness of the evidence generated by TB treatment trials could be improved by implementing standards for best practice. METHODS: A global panel of experts participated in a Delphi process, using a 7-point Likert scale to score and revise draft standa...
Aung Kya Jai Maug, M A Hossain, Mourad Gumusboga, Tom Decroo et al.
S. M. Mazidur Rahman, Senjuti Kabir, Sabrina Choudhury, Sohag Miah et al.
Background/Objectives: Stool-based GeneXpert testing has become a useful approach for diagnosing pediatric pulmonary tuberculosis (PTB). This study compared two stool-processing methods, centrifugation-based processing (CBP) and simple one-step (SOS), for detecting PTB in children using Xpert MTB/RI...
Arifa Nazneen (832053), Tanjina Rahman (9606820), Aazia Hossain (9589916), Anjan Kumar Saha (22331809) et al.
[Reprinted from GADM (<a href="https://gadm.org/license.html" target="_blank">https://gadm.org/license.html</a>) under a CC BY license, with permission from Robert Hijmans, original copyright ©GADM].
Arifa Nazneen, Tanjina Rahman, Aazia Hossain, Anjan Saha et al.
Tea garden populations with poor socio-economic status are at risk of developing TB. The active case finding (ACF) approach is effective in finding TB among the people at risk. We have conducted ACF for TB to find people with presumptive TB in the tea gardens of Sylhet division to identify TB diseas...
Md Abdul Hasib Joarder, Pretom Saha, Subhash Chandra Chakraborty, Khadiza Akter et al.
OBJECTIVES: Tuberculosis is a global public health challenge, disproportionately affecting adolescents in low-and middle-income countries. Malnutrition worsens immune function, delays recovery and increases the risk of treatment failure in Tuberculosis patients. The objectives of this study was to a...
S. M. Mazidur Rahman, Noshin Nawer Ruhee, A.F.M.Y. Haider, Md Jahid Hasan et al.
INTRODUCTION: Early detection of drug resistance in patients with tuberculosis (TB) is crucial for prompt and effective treatment. This study evaluated the performance of Xpert MTB/XDR assay (Xpert XDR) for detecting resistance to isoniazid (INH), fluoroquinolones (FLQ), aminoglycosides (AMG), and e...