Sumon Ghosh, Md Sohel Rana, Md Kamrul Islam, Sukanta Chowdhury et al.
Vaccinating dogs against rabies is an effective means of reducing human rabies. We subjected 1327 clinically diagnosed human rabies death and mass dog vaccination (MDV) data during 2006-2018 to quantify the impacts of MDV on human rabies incidence in Bangladesh and a subset of rabies death data (422...
Moazzem Hossain, Kamruddin Ahmed, Aung Swi Prue Marma, Sohrab Hossain et al.
Globally, Bangladesh ranks third in the number of human deaths from rabies. Although dogs are the principal known transmitters of rabies and knowledge of dog populations is essential for effective national control and proper planning, dog control programs are scarce in Bangladesh. Our objective was ...
Toshihiro Mita, Jun Ohashi, Meera Venkatesan, Aung Swi Prue Marma et al.
BACKGROUND: Monitoring the prevalence of drug resistant Plasmodium falciparum is essential for effective malaria control. Resistance to pyrimethamine and sulfadoxine increases as mutations accumulate in the parasite genes encoding dihydrofolate reductase (dhfr) and dihydropteroate synthase (dhps), r...
Kazuyuki Tanabe, Sedigheh Zakeri, Nirianne Palacpac, Manada Afsharpad et al.
Recent reports on the decline of the efficacy of artemisinin-based combination therapies (ACTs) indicate a serious threat to malaria control. The endoplasmic/sarcoplasmic reticulum Ca(2+)-ATPase ortholog of Plasmodium falciparum (PfSERCA) has been suggested to be the target of artemisinin and its de...
Aung Swi Prue Marma, Toshihiro Mita, Hideaki Eto, Takahiro Tsukahara et al.
In Bangladesh, despite the official introduction of artemisinin combination therapy in 2004, chloroquine+sulfadoxine/pyrimethamine has been used for the treatment of uncomplicated malaria. To assess the distribution of pfcrt, pfmdr1, dhfr, and dhps genotypes in Plasmodium falciparum, we conducted ho...
Maisha Khair Nima, Angana Mukherjee, Saiful Arefeen Sazed, Muhammad Riadul Haque Hossainey et al.
Malaria elimination is a Millennium Development Goal. Artemisinins, fast-acting antimalarial drugs, have played a key role in malaria elimination. Emergence of artemisinin resistance threatens the global elimination of malaria. Over the last decade, advanced clinical and laboratory methods have docu...
Kamala Thriemer, Wasif Ali Khan, Peter Starzengrüber, Rashidul Haque et al.
The combination of artemether and lumefantrine was introduced in 2005 as the official first line therapy for uncomplicated falciparum malaria in Bangladesh. Fresh P. falciparum samples from patients with acute uncomplicated falciparum malaria who presented to the field site at the Bandarban Sadar Ho...
Matthias G. Vossen, Rashidul Haque, Peter Starzengrüber, Wasif Ali Khan et al.
In recent clinical trials acithromycin in combination with artemisinin derivatives proved to be a promising combination therapy with indifferent to synergistic interaction. The aim of the present study was the assessment of optimal combination ratios for dihydroartemisinin and azithromycin for the t...
Maisha Khair Nima, Saiful Arefeen Sazed, Angana Mukherjee, Muhammad Riadul Haque Hossainey et al.
Abstract The emergence of resistance to artemisinin drugs threatens global malaria control. Resistance is widely seen in South East Asia (SEA) and Myanmar, but not comprehensively assessed in Bangladesh. This is due to lack of measuring parasite clearance times in response to drug treatment, a gold ...
Aung Swi Prue Marma