Dinesh Mondal, Shri Prakash Singh, Narendra Kumar, Anand Joshi et al.
OBJECTIVE: We sought to estimate visceral leishmaniasis (VL) burden in Bangladesh, India, and Nepal and document care-seeking behaviour for VL to provide baseline information for monitoring the VL elimination program and identify options for improved case finding and management. DESIGN: A cross-sect...
Dinesh Mondal, Prakash Ghosh, Md Anik Ashfaq Khan, Faria Hossain et al.
BACKGROUND: Leishmania donovani (LD) is a protozoan parasite transmitted to humans from sand flies, which causes Visceral Leishmaniasis (VL). Currently, the diagnosis is based on presence of the anti-LD antibodies and clinical symptoms. Molecular diagnosis would require real-time PCR, which is not e...
Greg Matlashewski, Byron Arana, Axel Kroeger, S. Battacharya et al.
The world's burden of infectious diseases can be substantially reduced by more-effective use of existing interventions. Advances in case detection, diagnosis, and treatment strategies have made it possible to consider the elimination of visceral leishmaniasis in the Indian subcontinent. The priority...
Anand Joshi, J P Narain, C Prasittisuk, Rajesh Bhatia et al.
Data on the burden of visceral leishmaniasis (VL) in Indian sub-continent are vital for elimination programme planners for estimating resource requirements, effective implementation and monitoring of elimination programme. In Indian sub-continent, about 200 million population is at risk of VL. Nearl...
Anand Joshi, Murari Lal Das, Shireen Akhter, Rajib Chowdhury et al.
BACKGROUND: Bangladesh, India and Nepal are working towards the elimination of visceral leishmaniasis (VL) by 2015. In 2005 the World Health Organization/Training in Tropical Diseases launched an implementation research programme to support integrated vector management for the elimination of VL from...
Siddhivinayak Hirve, Marleen Boelaert, Greg Matlashewski, Dinesh Mondal et al.
BACKGROUND: As Bangladesh, India and Nepal progress towards visceral leishmaniasis (VL) elimination, it is important to understand the role of asymptomatic Leishmania infection (ALI), VL treatment relapse and post kala-azar dermal leishmaniasis (PKDL) in transmission. METHODOLOGY/ PRINCIPAL FINDING:...
Dinesh Mondal, Kamrul Nahar Nasrin, M. Mamun Huda, Mamun Kabir et al.
OBJECTIVES: To support the Bangladesh National Kala-azar Elimination Programme (NKEP), we investigated the feasibility of using trained village volunteers for detecting post-kala-azar dermal leishmaniasis (PKDL) cases, using polymerase chain reaction (PCR) for confirmation of diagnosis and treatment...
Siddhivinayak Hirve, Axel Kroeger, Greg Matlashewski, Dinesh Mondal et al.
BACKGROUND: The decade following the Regional Strategic Framework for Visceral Leishmaniasis (VL) elimination in 2005 has shown compelling progress in the reduction of VL burden in the Indian subcontinent. The Special Programme for Research and Training in Tropical Diseases (TDR), hosted by the Worl...
Shyam Sundar, Dinesh Mondal, Suman Rijal, Sujit Bhattacharya et al.
Visceral leishmaniasis (VL), known as kala azar, is a parasitic disease caused by Leishmania transmitted by sand flies which causes about 59 000 deaths per year and 2.4 million disability-adjusted life years (DALYs) lost (World Health Report 2002). India is the most affected country in the world and...
Rajib Chowdhury, M. Mamun Huda, Vijay Kumar, Pradeep Das et al.
Although, when applied under controlled conditions in India and Nepal, indoor residual spraying (IRS) has been found to reduce sandfly densities significantly, it is not known if IRS will be as effective when applied generally in these countries, via the national programmes for the elimination of vi...
Piero Olliaro, Tushar A. K. M. Shamsuzzaman, Baburam Marasini, A C Dhariwal et al.
Nazir, A; Mondal, D; Banjara, MR; Das, P; Sundar, S; Rijal, S; Arana, B; Alvar, J; Argaw, D; Peeling, RW; Kroeger, A; Matlashewski, G (2017) Investments in Research and Surveillance Are Needed to Go Beyond Elimination and Stop Transmission of Leishmania in the Indian Subcontinent. PLoS neglected tro...
Dinesh Mondal, M. Mamun Huda, Mithun Kumar Karmoker, Debashis Ghosh et al.
The effect of insecticide-treated materials on reducing visceral leishmaniasis (VL) is disputable. In Bangladesh, we evaluated the effect of a community-based intervention with insecticide impregnation of existing bed-nets in reducing VL incidence. This intervention reduced VL by 66.5%. Widespread b...
Rajib Chowdhury, Vijay Kumar, Dinesh Mondal, Murari Lal Das et al.
BACKGROUND: Visceral leishmaniasis (VL), also known as kala-azar in the Indian sub-continent (ISC), is a major public health concern in Bangladesh, India, and Nepal, where it is caused by Leishmania donovani transmitted by the sand fly Phlebotomus argentipes. Various ecological parameters including ...
Dinesh Mondal, Mohammad Shafiul Alam, Zehadul Karim, Rashidul Haque et al.
Objectives Kala-azar or visceral leishmaniasis is one of the major vector-borne diseases in Bangladesh. The disease is transmitted by sandfly. The incidence of the disease, which has been increasing since the early eighties, must be reduced by taking adequate vector-control measures. The objective o...
Shri Prakash Singh, Siddhivinayak Hirve, M. Mamun Huda, Megha Raj Banjara et al.
BACKGROUND: The VL elimination strategy requires cost-effective tools for case detection and management. This intervention study tests the yield, feasibility and cost of 4 different active case detection (ACD) strategies (camp, index case, incentive and blanket approach) in VL endemic districts of I...