William A. Petri, Rashidul Haque, Barbara J. Mann
Entamoeba histolytica, as its name suggests, is an enteric parasite with a remarkable ability to lyse host tissues. However, the interaction of the parasite with the host is more complex than solely destruction and invasion. It is at the host-parasite interface that cell-signaling events commit the ...
B Ogunkolade, Barbara J. Boucher, Jean M. Prahl, Stephen A. Bustin et al.
Associations have been reported between vitamin D receptor (VDR) gene polymorphisms, type 1 diabetes, insulin secretion, and the insulin resistance syndrome. As VDR polymorphisms have no known functional significance, these findings may implicate a variant of the VDR gene or a locus in linkage diseq...
G. A. Hitman, Nasima Mannan, Michael McDermott, E Aganna et al.
Syed Azizur Rahman, Tara Kielmann, Barbara McPake, Charles Normand
Despite the wealth of studies on health and healthcare-seeking behaviour among the Bengali population in Bangladesh, relatively few studies have focused specifically on the tribal groups in the country. This study aimed at exploring the context, reasons, and choices in patterns of healthcare-seeking...
Nasima Mannan, Barbara J. Boucher, Stephen Evans
Type 2 diabetes is commoner in Asians than Caucasians. Many nitrosamines are diabetogenic, causing both type 2 and type 1 diabetes. Of CD1 mice fed with betel-nut or associated nitrosamines 8.5% develop glucose intolerance with marked obesity. Glycaemia and anthropometric risk markers for type 2 dia...
Louise T. Day, Qazi Sadeq-ur Rahman, Ahmed Ehsanur Rahman, Nahya Salim et al.
BACKGROUND: Progress in reducing maternal and neonatal deaths and stillbirths is impeded by data gaps, especially regarding coverage and quality of care in hospitals. We aimed to assess the validity of indicators of maternal and newborn health-care coverage around the time of birth in survey data an...
L. E. Murray-Kolb, Zeba Rasmussen, Rebecca J. Scharf, Muneera A. Rasheed et al.
More epidemiological data are needed on risk and protective factors for child development. In The Etiology, Risk Factors and Interactions of Enteric Infections and Malnutrition and the Consequences for Child Health and Development (MAL-ED) cohort study, we assessed child development in a harmonious ...
W. Garry John, Kate Noonan, Nasima Mannan, Barbara J. Boucher
W Ogunkolade, Barbara J. Boucher, Stephen A. Bustin, Jacky M. Burrin et al.
CONTEXT: Vitamin D deficiency, common in South Asians, is a risk factor for metabolic syndrome, type 2 diabetes, and ischemic heart disease. Vitamin D receptor (VDR) activation depends on activated vitamin D [1,25-dihydroxyvitamin D (1,25(OH)(2)D)] concentration, reflecting opposing actions of 25-hy...
Augusto Di Castelnuovo, Simona Costanzo, Marialaura Bonaccio, Patrick McElduff et al.
AIM: To test the association of alcohol consumption with total and cause-specific mortality risk. DESIGN: Prospective observational multi-centre population-based study. SETTING: Sixteen cohorts (15 from Europe) in the MOnica Risk, Genetics, Archiving and Monograph (MORGAM) Project. PARTICIPANTS: A t...
V. Oliveira‐Cruz, Jeanne Kowalski, Barbara McPake
Discussions on the use of anti-retroviral drugs (ARVs) in developing countries have in the past focused on the limitations caused by the high cost of the drugs and by the lack of health system capacity to adequately deliver and make use of them (Colebunders et al. 2000; The New York Times 2001). An ...
Christina Åhrén, Leif Gothefors, Barbara J. Stoll, Mogjiborahman Salek et al.
Fecal Escherichia coli isolates from 196 patients with watery diarrhea and 68 healthy individuals (controls) were analyzed in Bangladesh immediately after isolation for the presence of colonization factor antigen (CFA) I or II (CFA/I or CFA/II, respectively) by a mannose-resistant hemagglutination (...
W. Garry John, Kate Noonan, Nasima Mannan, Barbara J. Boucher
Background Although hypovitaminosis D has been suggested to increase the risk of heart disease, its relation to components of the fasting lipid profile has not been clarified for specific ethnic groups. Objective The objective was to determine the relation of circulating 25-hydroxyvitamin D [25(OH)D...
OA Obeid, Nasima Mannan, Gilbert J. Perry, RA Iles et al.
Paul Kelly, Kelley VanBuskirk, David Coomes, Samer Mouksassi et al.
BACKGROUND: Environmental enteric dysfunction (EED) is an asymptomatic intestinal disorder associated with growth impairment, delayed neurocognitive development, and impaired oral vaccine responses. OBJECTIVES: We set out to develop and validate a histopathologic scoring system on duodenal biopsies ...