Mihai Pop, Alan W. Walker, Joseph N. Paulson, Brianna Lindsay et al.
BACKGROUND: Diarrheal diseases continue to contribute significantly to morbidity and mortality in infants and young children in developing countries. There is an urgent need to better understand the contributions of novel, potentially uncultured, diarrheal pathogens to severe diarrheal disease, as w...
Brianna Lindsay, John B. Ochieng, Usman N. Ikumapayi, Aliou Touré et al.
Estimates of the prevalence of Shigella spp. are limited by the suboptimal sensitivity of current diagnostic and surveillance methods. We used a quantitative PCR (qPCR) assay to detect Shigella in the stool samples of 3,533 children aged <59 months from the Gambia, Mali, Kenya, and Bangladesh, with ...
Mahamud‐ur Rashid, Mathieu Almeida, Andrew S. Azman, Brianna Lindsay et al.
Vibrio cholerae causes cholera, a severe diarrheal disease. Understanding the local genetic diversity and transmission of V. cholerae will improve our ability to control cholera. Vibrio cholerae isolates clustered in genetically related groups (clonal complexes, CC) by multilocus variable tandem-rep...
S. Goedhart, W. D. Cotton, F. Camilo, M. A. Thompson et al.
ABSTRACT We present the SARAO MeerKAT Galactic Plane Survey (SMGPS), a 1.3 GHz continuum survey of almost half of the Galactic Plane (251° ≤l ≤ 358° and 2° ≤l ≤ 61° at |b| ≤ $1{_{.}^{\circ}}5$). SMGPS is the largest, most sensitive, and highest angular resolution 1 GHz survey of the plane yet carrie...
Brianna Lindsay, Joe Oundo, M. Anowar Hossain, Martín Antonio et al.
Pathogens in the gastrointestinal tract exist within a vast population of microbes. We examined associations between pathogens and composition of gut microbiota as they relate to Shigella spp./enteroinvasive Escherichia coli infection. We analyzed 3,035 stool specimens (1,735 nondiarrheal and 1,300 ...
Brianna Lindsay, Debasish Saha, Doh Sanogo, Sumon Kumar Das et al.
Molecular identification of the invasion plasmid antigen-H (ipaH) gene has been established as a useful detection mechanism for Shigella spp. The Global Enteric Multicenter Study (GEMS) identified the etiology and burden of moderate-to-severe diarrhea (MSD) in sub-Saharan Africa and south Asia using...
Brianna Lindsay, Mihai Pop, Martín Antonio, Alan W. Walker et al.
Cultivation-based assays combined with PCR or enzyme-linked immunosorbent assay (ELISA)-based methods for finding virulence factors are standard methods for detecting bacterial pathogens in stools; however, with emerging molecular technologies, new methods have become available. The aim of this stud...