Heidi Kreibich, Anne F. Van Loon, Kai Schröter, Philip J. Ward et al.
Abstract Risk management has reduced vulnerability to floods and droughts globally 1,2 , yet their impacts are still increasing 3 . An improved understanding of the causes of changing impacts is therefore needed, but has been hampered by a lack of empirical data 4,5 . On the basis of a global datase...
Luregn J. Schlapbach, R. Scott Watson, Lauren R. Sorce, Andrew C. Argent et al.
Importance: Sepsis is a leading cause of death among children worldwide. Current pediatric-specific criteria for sepsis were published in 2005 based on expert opinion. In 2016, the Third International Consensus Definitions for Sepsis and Septic Shock (Sepsis-3) defined sepsis as life-threatening org...
David M. Reimers, Stephan Thernstrom
Groups and Definitions Acadians Marietta M. LeBreton Afghans David C. Champagne Africans Afro-Americans Thomas C. Holt Albanians Aleuts Dorothy M. Jones Alsatians Frederick C. Luebke American Indians Edward H. Spicer Amish John A. Hostetler Anglo-American Anglo-Saxon Appalachians Dwight Billings and...
Md. Abdul Mazid, Carl Ward, Zhiwei Luo, Chuanyu Liu et al.
After fertilization, the quiescent zygote experiences a burst of genome activation that initiates a short-lived totipotent state. Understanding the process of totipotency in human cells would have broad applications. However, in contrast to in mice 1,2 , demonstration of the time of zygotic genome a...
Mohanraj Ramachandran, Carl D. Kirkwood, Leanne Unicomb, Nigel A. Cunliffe et al.
Between 1992 and 1998, serotype G9 human rotavirus (RV) strains have been detected in 10 countries, including Thailand, India, Brazil, Bangladesh, Malawi, Italy, France, the United States, the United Kingdom, and Australia, suggesting the possible emergence of the fifth common serotype worldwide. Un...
Minsheng You, Fushi Ke, Shijun You, Zhangyan Wu et al.
The diamondback moth, Plutella xylostella is a cosmopolitan pest that has evolved resistance to all classes of insecticide, and costs the world economy an estimated US $4-5 billion annually. We analyse patterns of variation among 532 P. xylostella genomes, representing a worldwide sample of 114 popu...
Sheel Bansal, Irena F. Creed, Brian A. Tangen, Scott D. Bridgham et al.
Abstract Wetlands cover a small portion of the world, but have disproportionate influence on global carbon (C) sequestration, carbon dioxide and methane emissions, and aquatic C fluxes. However, the underlying biogeochemical processes that affect wetland C pools and fluxes are complex and dynamic, m...
Zachary J. Ward, Jennifer M. Yeh, Ché L. Reddy, Apoorva Gomber et al.
BACKGROUND Previous studies of type 1 diabetes in childhood and adolescence have found large variations in reported incidence around the world. However, it is unclear whether these reported incidence levels are impacted by differences in country health systems and possible underdiagnosis and if so, ...
Richard L. Ward, Carl D. Kirkwood, D. S. Sander, Vicki E. Smith et al.
The G1P1A[8] rotavirus vaccine candidate 89-12, the precursor to Rotarix, stimulated high titers of neutralizing antibodies to non-G1/P1A[8] serotypes of human rotavirus in naturally infected subjects before attenuation by cell-culture passages. These responses were greatly diminished in young infan...
Denham S. Ward, Mark R. Williams, John W. Berkenbosch, Maala Bhatt et al.
The Sedation Consortium on Endpoints and Procedures for Treatment, Education, and Research, established by the Analgesic, Anesthetic, and Addiction Clinical Trial Translations, Innovations, Opportunities, and Networks, a public-private partnership with the US Food and Drug Administration, convened a...
Christian Geroin, Carlo Alberto Artusi, Jorik Nonnekes, Camila Aquino et al.
Axial postural abnormalities are common and disabling motor complications of Parkinson's disease (PD) and parkinsonism. They consist of abnormal trunk or neck postures in the upright position, often interfering with daily life activities.1-5 A high number of patients with PD may develop one or more ...
Mohammad Yasir Essar, Hiba Khan, Maryam Salma Babar, Mohammad Mehedi Hasan et al.
Afghanistan, a country with fragile healthcare infrastructure, was hit hard by the outrageous spread of the COVID-19 pandemic. When the virus reached the borders, it was apparent that the country would suffer to a great extent, especially with regards to the healthcare sector. In the aftermath of th...
Senjuti Saha, Sudipta Saha, Naito Kanon, Yogesh Hooda et al.
BACKGROUND: Respiratory syncytial virus (RSV) is a leading cause of paediatric hospital admissions worldwide, straining health systems. A lack of data on the burden of RSV infections and the impact on health systems in resource-limited settings hinders evidence-based policy decisions. Here, we aimed...
Refath Farzana, Stephan Jürgen Harbarth, Ly‐Mee Yu, Edoardo Carretto et al.
Background: This study aimed to evaluate the trends in antimicrobial prescription during the first 1.5 years of COVID-19 pandemic. Methods: This was an observational, retrospective cohort study using patient-level data from Bangladesh, Brazil, India, Italy, Malawi, Nigeria, South Korea, Switzerland ...
Sarwat Mahmud, Kevin van Zandvoort, Ling Guo, You Li et al.
BACKGROUND: Low-income and middle-income countries (LMICs) bear the greatest burden of respiratory syncytial virus (RSV) disease. WHO recommends passive immunisation to protect infants younger than 6 months and, in some strategies, infants up to age 12 months, but detailed age data are needed to det...