Md. Ismail Hosen, Mahdi Sheikh, Maria I. Zvereva, Ghislaine Scélo et al.
BACKGROUND: Detecting pre-clinical bladder cancer (BC) using urinary biomarkers may provide a valuable opportunity for screening and management. Telomerase reverse transcriptase (TERT) promoter mutations detectable in urine have emerged as promising BC biomarkers. METHODS: We performed a nested case...
Md. Ismail Hosen, Nathalie Forey, Geoffroy Durand, Catherine Voegele et al.
Somatic mutations in the telomerase reverse transcriptase (TERT) promoter regions are frequent events in urothelial cancer (UC) and their detection in urine (supernatant cell-free DNA or DNA from exfoliated cells) could serve as putative non-invasive biomarkers for UC detection and monitoring. Howev...