David F. Choy, Kevin M. Hart, Lee A. Borthwick, Aarti Shikotra et al.
Increasing evidence suggests that asthma is a heterogeneous disorder regulated by distinct molecular mechanisms. In a cross-sectional study of asthmatics of varying severity (n = 51), endobronchial tissue gene expression analysis revealed three major patient clusters: TH2-high, TH17-high, and TH2/17...
Rosalind Edwards, Bogusia Temple, Claire Alexander
This article explores the experiences of people who need interpreters to gain access to and use of a range of services, drawing on semi-structured interviews with people from Chinese, Kurdish, Bangladeshi, Indian and Polish minority ethnic groups living in Manchester and London, UK. We describe our ...
Lorcan McGarvey, Claire A. Butler, Susan Stokesberry, Liam Polley et al.
Background The airway epithelium is exposed to a range of physical and chemical irritants in the environment that are known to trigger asthma. Transient receptor potential (TRP) cation channels play a central role in sensory responses to noxious physical and chemical stimuli. Recent genetic evidence...
Laura Vang Rasmussen, Ingo Graß, Zia Mehrabi, Olivia M. Smith et al.
Agricultural simplification continues to expand at the expense of more diverse forms of agriculture. This simplification, for example, in the form of intensively managed monocultures, poses a risk to keeping the world within safe and just Earth system boundaries. Here, we estimated how agricultural ...
Megan E. Carey, Zoe A. Dyson, Danielle J. Ingle, Afreenish Amir et al.
Background: serovar Typhi (Typhi) genomic data to inform public health action. This analysis, which marks 22 years since the publication of the first Typhi genome, represents the largest Typhi genome sequence collection to date (n=13,000). Methods: This is a meta-analysis of global genotype and anti...
Claire Alexander
Based on a recent empirical project on 'the Bengal diaspora', the paper explores the construction and contestation of meanings around the iconic East London street, Brick Lane. Taking the 2006 protests around the film Brick Lane as its starting point, the paper draws on original interviews conducted...
Cormac McCarthy, Francesco Bonella, Marissa O’Callaghan, Clairelyne Dupin et al.
BACKGROUND: Pulmonary alveolar proteinosis (PAP) is a rare syndrome caused by several distinct diseases leading to progressive dyspnoea, hypoxaemia, risk of respiratory failure and early death due to accumulation of proteinaceous material in the lungs. Diagnostic strategies may include computed tomo...
Claire Alexander, Joya Chatterji, Annu Jalais
India’s partition in 1947 and the creation of Bangladesh in 1971 saw the displacement and resettling of millions of Muslims and Hindus, resulting in profound transformations across the region. A third of the region’s population sought shelter across new borders, almost all of them resettling in the ...
Claire Alexander
Drawing on new empirical research on ‘the Bengal diaspora’, this paper explores the struggle over Bangladeshi identity in East London, as exemplified in the monument of the Shahid Minar and the related celebration of Ekushe, which marks the beginning of the Bangladesh national liberation struggle. B...
Raquel Rubio-Acero, Jessica Beyerl, Maximilian Muenchhoff, Marc Sancho Roth et al.
Wastewater-based epidemiology (WBE) is a tool now increasingly proposed to monitor the SARS-CoV-2 burden in populations without the need for individual mass testing. It is especially interesting in metropolitan areas where spread can be very fast, and proper sewage systems are available for sampling...
JONATHAN H. SHANKS, CLAIRE M. HILL, TERENCE R. J. LAPPIN, Alexander P. Maxwell
Erythropoietin (EPO) is the main humoral stimulus of erythropoiesis. In adult mammals, the kidney releases EPO in response to hypoxic stress. Conflicting data have suggested either renal tubular or peritubular cell origins of EPO synthesis in vivo. In situ hybridization studies were performed to def...
Claire Alexander
Transnational marriage has been at the centre of controversies around migration control and multiculturalism in Britain in the past decade, with South Asian Muslim women placed at the heart of concerns around integration, segregation and ‘parallel lives’. Such discourses perpetuate a pathologised an...
Clare Mc Keaveney, Joanne Reid, Claire Carswell, Ann Bonner et al.
BACKGROUND: Globally, renal healthcare practitioners provide intensive and protracted support to a highly complex multi-morbid patient population however knowledge about the impact of COVID-19 on these practitioners is extremely limited. OBJECTIVE: This study aimed to explore the experiences of COVI...
Claire Alexander, Shahzad Firoz, Naaz Rashid
According to the 2001 census, 283,063 people of Bangladeshi heritage were living in Britain. This amounts to 0.5% of the total population of the UK and 6.1% of the ethnic minority population (unless otherwise stated, figures are based on data from the 2001 census). Of these, 154,000 people were born...
Claire Alexander, S. Carey, Suzanne Hall, Julia King et al.
As part of a two-year research project focusing on Brick Lane’s restaurant and retail sectors, the report highlights the unique contribution of the Bangladeshi community to Brick Lane and its world-renowned curry restaurants. Beyond Banglatown analyses Brick Lane’s rapid gentrification over the last...