Megan E. Carey, Zoe A. Dyson, Danielle J. Ingle, Afreenish Amir et al.
Background: serovar Typhi (Typhi) genomic data to inform public health action. This analysis, which marks 22 years since the publication of the first Typhi genome, represents the largest Typhi genome sequence collection to date (n=13,000). Methods: This is a meta-analysis of global genotype and anti...
Elisabeth Njamkepo, Nizar Fawal, Alicia Tran-Dien, Jane Hawkey et al.
Together with plague, smallpox and typhus, epidemics of dysentery have been a major scourge of human populations for centuries1. A previous genomic study concluded that Shigella dysenteriae type 1 (Sd1), the epidemic dysentery bacillus, emerged and spread worldwide after the First World War, with no...
Caroline Rouard, Elisabeth Njamkepo, Marie‐Laure Quilici, François‐Xavier Weill
In 2022, the burden of cholera-an acute watery diarrheal disease caused by Vibrio cholerae serogroup O1 (or more rarely O139) bacteria, which produce cholera toxin-remains high in many African and Asian countries. In the last few years, microbial genomics has made it possible to define the bacterial...
Megan E. Carey, Zoe A. Dyson, Danielle J. Ingle, Afreenish Amir et al.
Abstract The Global Typhoid Genomics Consortium was established to bring together the typhoid research community to aggregate and analyse Salmonella enterica serovar Typhi (Typhi) genomic data to inform public health action. This analysis, which marks twenty-one years since the publication of the fi...
Megan E. Carey, Zoe A. Dyson, Danielle J. Ingle, Afreenish Amir et al.
An analysis of the largest Salmonella Typhi genome collection to date (n=13,000) provides an updated overview of global genome diversity and antimicrobial resistance trends over time to inform public health action.