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Results for “"Fan Zhang"”

16+ results

Cardiovascular Risk and Events in 17 Low-, Middle-, and High-Income Countries

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Salim Yusuf, Sumathy Rangarajan, Koon Teo, Shofiqul Islam et al.

Journal: New England Journal of MedicineYear: 2014Citations: 991

BACKGROUND: More than 80% of deaths from cardiovascular disease are estimated to occur in low-income and middle-income countries, but the reasons are unknown. METHODS: We enrolled 156,424 persons from 628 urban and rural communities in 17 countries (3 high-income, 10 middle-income, and 4 low-income ...

Health SciencesMedicinePublic Health, Environmental and Occupational HealthOpen Access
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Circular RNA DLGAP4 Ameliorates Ischemic Stroke Outcomes by Targeting miR-143 to Regulate Endothelial-Mesenchymal Transition Associated with Blood–Brain Barrier Integrity

Verified

Ying Bai, Yuan Zhang, Bing Han, Li Yang et al.

Journal: Journal of NeuroscienceYear: 2017Citations: 381

Circular RNAs (circRNAs) are highly expressed in the CNS and regulate physiological and pathophysiological processes. However, the potential role of circRNAs in stroke remains largely unknown. Here, we show that the circRNA DLGAP4 (circDLGAP4) functions as an endogenous microRNA-143 (miR-143) sponge...

Life SciencesBiochemistry, Genetics and Molecular BiologyMolecular BiologyOpen Access
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Modulating Electronic Structure of Metal‐Organic Framework for Efficient Electrocatalytic Oxygen Evolution

Verified

Ziqian Xue, Yinle Li, Yawei Zhang, Wei Geng et al.

Journal: Advanced Energy MaterialsYear: 2018Citations: 299

Abstract Exploring effective electrocatalysts for oxygen evolution reaction (OER) is a crucial requirement of many energy storage and conversion systems, involving fuel cells, water splitting, and metal–air batteries. Herein, a heterogeneity metal‐organic framework (MOF) is prepared by the assemblin...

Physical SciencesEnergyRenewable Energy, Sustainability and the Environment
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A chromosome-level genome of the spider <i>Trichonephila antipodiana</i> reveals the genetic basis of its polyphagy and evidence of an ancient whole-genome duplication event

Verified

Zheng Fan, Yuan Tao, Piao Liu, Lu-Yu Wang et al.

Journal: GigaScienceYear: 2021Citations: 291

BACKGROUND: The spider Trichonephila antipodiana (Araneidae), commonly known as the batik golden web spider, preys on arthropods with body sizes ranging from ∼2 mm in length to insects larger than itself (>20‒50 mm), indicating its polyphagy and strong dietary detoxification abilities. Although it h...

Life SciencesBiochemistry, Genetics and Molecular BiologyMolecular BiologyOpen Access
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Anti‐Corrosive and Zn‐Ion‐Regulating Composite Interlayer Enabling Long‐Life Zn Metal Anodes

Verified

Shuang Zhou, Yaping Wang, Haotian Lu, Yifang Zhang et al.

Journal: Advanced Functional MaterialsYear: 2021Citations: 234

Abstract The Zn metal anode is considered one of the most promising anode choices for aqueous Zn‐based batteries. Nevertheless, dendrites and intricate side reactions have hindered its usage. Herein, an elastic and anti‐corrosive interlayer is introduced to address the problem. The idiosyncratic die...

Physical SciencesEngineeringElectrical and Electronic Engineering
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Circular RNA <i>TLK1</i> Aggravates Neuronal Injury and Neurological Deficits after Ischemic Stroke via miR-335-3p/TIPARP

Verified

Fangfang Wu, Bing Han, Shusheng Wu, Li Yang et al.

Journal: Journal of NeuroscienceYear: 2019Citations: 205

Circular RNAs (circRNAs) are expressed at high levels in the brain and are involved in various CNS diseases. However, the potential role of circRNAs in ischemic stroke-associated neuronal injury remains largely unknown. Here, we investigated the important functions of circRNA TLK1 (circTLK1) in this...

Life SciencesBiochemistry, Genetics and Molecular BiologyMolecular BiologyOpen Access
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A novel protein AXIN1-295aa encoded by circAXIN1 activates the Wnt/β-catenin signaling pathway to promote gastric cancer progression

Verified

Yin Peng, Yidan Xu, Xiaojing Zhang, Shiqi Deng et al.

Journal: Molecular CancerYear: 2021Citations: 193

Abstract Background Circular RNA (circRNA), a subclass of non-coding RNA, plays a critical role in cancer tumorigenesis and metastasis. It has been suggested that circRNA acts as a microRNA sponge or a scaffold to interact with protein complexes; however, its full range of functions remains elusive....

Life SciencesBiochemistry, Genetics and Molecular BiologyMolecular BiologyOpen Access
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A Strategy for Architecture Design of Crystalline Perovskite Light‐Emitting Diodes with High Performance

Verified

Yifei Shi, Wen Wu, Hua Dong, Guangru Li et al.

Journal: Advanced MaterialsYear: 2018Citations: 190

Abstract All present designs of perovskite light‐emitting diodes (PeLEDs) stem from polymer light‐emitting diodes (PLEDs) or perovskite solar cells. The optimal structure of PeLEDs can be predicted to differ from PLEDs due to the different fluorescence dynamics and crystallization between perovskite...

Physical SciencesEngineeringElectrical and Electronic Engineering
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Association of Diabetes With All-Cause and Cause-Specific Mortality in Asia

Verified

Jae Jeong Yang, Danxia Yu, Wanqing Wen, Eiko Saito et al.

Journal: JAMA Network OpenYear: 2019Citations: 174

Importance: Asia is home to the largest diabetic populations in the world. However, limited studies have quantified the association of diabetes with all-cause and cause-specific mortality in Asian populations. Objectives: To evaluate the association of diabetes with all-cause and cause-specific mort...

Health SciencesMedicineEndocrinology, Diabetes and MetabolismOpen Access
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Tumor cell-released autophagosomes (TRAPs) promote immunosuppression through induction of M2-like macrophages with increased expression of PD-L1

Verified

Zhifa Wen, Hongxiang Liu, Rong Gao, Meng Zhou et al.

Journal: Journal for ImmunoTherapy of CancerYear: 2018Citations: 170

<h3>Background</h3> Tumor-associated macrophages (TAMs) facilitate tumor progression via establishment of an immunosuppressive tumor microenvironment (TME). However, it is poorly understood how tumor cells could functionally modulate TAMs. Our previous work indicated that tumor cell-released autopha...

Life SciencesBiochemistry, Genetics and Molecular BiologyMolecular BiologyOpen Access
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Global, Regional, and National Epidemiology of Diabetes in Children From 1990 to 2019

Verified

Kexin Zhang, Chengxia Kan, Fang Han, Jingwen Zhang et al.

Journal: JAMA PediatricsYear: 2023Citations: 165

Importance: Diabetes in children is a global epidemic that causes various medical conditions associated with an increased incidence of premature death. Objective: To investigate the trends in diabetes incidence, mortality, and disability-adjusted life-years (DALYs) in children, with risk factors for...

Health SciencesMedicineEndocrinology, Diabetes and MetabolismOpen Access
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A cohort study of cancer among benzene-exposed workers in China: Overall results

Verified

Song-Nian Yin, Richard B. Hayes, Martha S. Linet, Guilan Li et al.

Journal: American Journal of Industrial MedicineYear: 1996Citations: 153

A large cohort study of 74,828 benzene-exposed and 35,805 unexposed workers employed between 1972 and 1987 in 12 cities in China were followed to determine mortality from all causes and the incidence of lymphohematopoietic malignancies and other hematologic disorders. Benzene-exposed study subjects ...

Life SciencesBiochemistry, Genetics and Molecular BiologyCancer Research
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Gasdermin D-dependent platelet pyroptosis exacerbates NET formation and inflammation in severe sepsis

Verified

Meiling Su, Chaofei Chen, Shaoying Li, Musheng Li et al.

Journal: Nature Cardiovascular ResearchYear: 2022Citations: 152

Platelets have emerged as key inflammatory cells implicated in the pathology of sepsis, but their contributions to rapid clinical deterioration and dysregulated inflammation have not been defined. Here, we show that the incidence of thrombocytopathy and inflammatory cytokine release was significantl...

Life SciencesBiochemistry, Genetics and Molecular BiologyMolecular BiologyOpen Access
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Fruit skin color and the role of anthocyanin

Verified

Emrul Kayesh, Lingfei Shangguan, Nicholas Kibet Korir, Xin Sun et al.

Journal: Acta Physiologiae PlantarumYear: 2013Citations: 151
Life SciencesBiochemistry, Genetics and Molecular BiologyMolecular Biology
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Efficient green InP-based QD-LED by controlling electron injection and leakage

Verified

Yangyang Bian, Xiaohan Yan, Fei Chen, Qian Li et al.

Journal: NatureYear: 2024Citations: 150

Green indium phosphide (InP)-based quantum dot light-emitting diodes (QD-LEDs) still suffer from low efficiency and short operational lifetime, posing a critical challenge to fully cadmium-free QD-LED displays and lighting 1-3 . Unfortunately, the factors that underlie these limitations remain uncle...

Physical SciencesMaterials ScienceMaterials Chemistry
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