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Results for “"Fatima Zohra Mokhfi"”

2 results

Alkaloid-based modulators of the PI3K/Akt/mTOR pathway for cancer therapy: Understandings from pharmacological point of view

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Fatima Zohra Mokhfi, Md. Al Amin, Mehrukh Zehravi, Sherouk Hussein Sweilam et al.

Journal: Chemico-Biological InteractionsYear: 2024Citations: 25

This review aims to summarize the role of alkaloids as potential modulators of the PI3K/Akt/mTOR (PAMT) pathway in cancer therapy. The PAMT pathway plays a critical role in cell growth, survival, and metabolism, and its dysregulation contributes to cancer hallmarks. In healthy cells, this pathway is...

Health SciencesMedicinePharmacology
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Resveratrol: A Natural Compound Targeting the PI3K/Akt/mTOR Pathway in Neurological Diseases

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Biswajit Kumar Utpal, Fatima Zohra Mokhfi, Mehrukh Zehravi, Sherouk Hussein Sweilam et al.

Journal: Molecular NeurobiologyYear: 2024Citations: 24

Neurological diseases (NDs), including neurodegenerative disorders and acute injuries, are a significant global health concern. The PI3K/Akt/mTOR pathway, a crucial signaling cascade, is responsible for the survival of cells, proliferation, and metabolism. Dysregulation of this pathway has been link...

Health SciencesMedicineGeriatrics and Gerontology
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