Meiling Su, Chaofei Chen, Shaoying Li, Musheng Li et al.
Platelets have emerged as key inflammatory cells implicated in the pathology of sepsis, but their contributions to rapid clinical deterioration and dysregulated inflammation have not been defined. Here, we show that the incidence of thrombocytopathy and inflammatory cytokine release was significantl...
Meng Zhang, Wenhai Sui, Yanqiu Xing, Jing Cheng et al.
The rennin-angiotensin-aldosterone system (RAAS) plays a critical role in the pathogenesis of diabetic cardiomyopathy, but the role of a member of RAAS, angiotensin IV (Ang IV), in this disease and its underlying mechanism are unclear. This study was aimed to clarify the effects of Ang IV and its do...
Fei Xue, Jing Cheng, Yan Liu, Cheng Cheng et al.
Abstract Angiotensin-converting enzyme 2 (ACE2) has proven beneficial in attenuating diabetic cardiomyopathy (DCM) but has been found to be a substrate of a disintegrin and metalloprotease protein-17 (ADAM17). However, whether ADAM17 plays a role in the pathogenesis and intervention of DCM is obscur...
Peng Fei, Md. Aslam Ali, Shaoying Gong, Qi Sun et al.
This study was conducted to analyze the antimicrobial activity of olive oil polyphenols extract (OOPE) against Cronobacter sakazakii. The antimicrobial effect was evaluated by minimum inhibitory concentration (MIC) and minimum bactericidal concentration (MBC) values, and survival of bacteria after t...
Ming Li, Congjiao Sun, Naiyi Xu, Peipei Bian et al.
Abstract The gene numbers and evolutionary rates of birds were assumed to be much lower than those of mammals, which is in sharp contrast to the huge species number and morphological diversity of birds. It is, therefore, necessary to construct a complete avian genome and analyze its evolution. We co...
Yufei Wang, Zezhou Liang, Xiangfei Liang, Xuemiao Wen et al.
Abstract The morphological features of the active layer has always been an important factor limiting the efficiency of organic solar cells (OSCs). Although halogen‐based additives capable of forming non‐covalent bonds with active molecules can effectively adjust the morphology of active layer, the i...
Linlin Meng, Yue Lu, Xinlu Wang, Cheng Cheng et al.
Cardiac fibrosis plays a key role in the progression of diabetic cardiomyopathy (DCM). Previous studies demonstrated the cardioprotective effects of natriuretic peptides. However, the effects of natriuretic peptide receptor C (NPRC) on cardiac fibrosis in DCM remains unknown. Here, we observed that ...
Jie Zhang, Lei Cao, Xiaohong Wang, Qian Li et al.
Renal fibrosis and inflammation are critical for the initiation and progression of hypertensive renal disease (HRD). However, the signaling mechanisms underlying their induction are poorly understood, and the role of tripartite motif-containing protein 31 (TRIM31), an E3 ubiquitin ligase, in HRD rem...
Jian Yang, Mei Dong, Xiao Meng, Yu Zhao et al.
OBJECTIVE: To test the hypothesis that chronic infusion of angiotensin-(1-7) [Ang-(1-7)] may dose-dependently inhibit atherosclerotic lesion formation by targeting vascular smooth muscle cells and a large dose of Ang-(1-7) may stabilize mature plaque by targeting macrophages. APPROACH AND RESULTS: I...
Cheng Cheng, Jie Zhang, Xiaodong Li, Fei Xue et al.
Abstract Previous studies suggested a beneficial effect of natriuretic peptides in animal models of cardiovascular disease, but the role of natriuretic peptide receptor C (NPRC) in the pathogenesis of atherosclerosis (AS) remains unknown. This study was designed to test the hypothesis that NPRC may ...
M. Afshar Alam, Fei Xue, Changyou Wang, Wanquan Ji
Wheat powdery mildew, caused by Blumeria graminis f. sp. Tritici is one of the most devastating diseases of common wheat worldwide. To date, 41 loci (Pm1 to Pm45, Pm18=Pm1c, Pm22=Pm1e, Pm23=Pm4c, Pm31=Pm21) with more than 60 genes/alleles for resistance to powdery mildew have been identified and loc...
Feimin Zhang, Yunzhu Qian, Hanbang Chen, Yang Xu et al.
Constructing biomimetic structure and incorporating bioactive molecules is an effective strategy to achieve a more favorable cell response. To explore the effect of electrospinning (ES) nanofibrous architecture and collagen I (COL I)-incorporated modification on tuning osteoblast response, a resorba...
Dachuan Guo, Zhenguo Wu, Fei Xue, Sha Chen et al.
BACKGROUND: The triglyceride-glucose (TyG) index has been linked to the onset, progression, and prognosis of cardiovascular disease (CVD) in middle-aged and elderly individuals. Nevertheless, the relationship between the TyG index and impaired cardiovascular fitness (CVF) remains unexplored in non-d...
Nianhong Wang, Xue-Yi Zhou, Shou‐Heng Shi, Shuo Zhang et al.
INTRODUCTION: Cadmium (Cd) is one of the most detrimental heavy metal pollutants, seriously affecting crop production and human health. Nucleobase-ascorbic acid transporters (NAT) are widely present in many living organisms including plants, animals and microbes; however, the role of NAT in plant Cd...
Yibo Li, Weizheng Meng, Yaxin Hou, Dongxu Li et al.
ABSTRACT: Mitophagy is involved in the development of various cardiovascular diseases, such as atherosclerosis, heart failure, myocardial ischemia/reperfusion injury, and hypertension. Mitophagy is essential for maintaining intracellular homeostasis and physiological function in most cardiovascular ...
Md Shipan Mia, Ping Yao, Xiaowei Zhu, Xue Fei Lei et al.
sample reached 98%, 97%, and 95% in 5-40 min for methylene blue, reactive orange GRN, and cationic violet X-5BLN, respectively. Different thermodynamic and kinetic models were used to check the best fit of the adsorption data. The results indicated that the Freundlich isotherm and pseudo first-order...
Yi-Han Iris Yin, Bin‐Bin Zhang, Jun Yang, Hui Sun et al.
Abstract The Einstein Probe (EP) achieved its first detection and localization of a bright X-ray flare, EP240219a, on 2024 February 19, during its commissioning phase. Subsequent targeted searches triggered by the EP240219a alert identified a faint, untriggered gamma-ray burst (GRB) in the archived ...
Xueguang Lu, Feilong Zhang, Liguo Zhu, Shan Peng et al.
Abstract Large-scale stretchable strain sensor arrays capable of mapping two-dimensional strain distributions have gained interest for applications as wearable devices and relating to the Internet of Things. However, existing strain sensor arrays are usually unable to achieve accurate directional re...
Jing Ma, Xiaoling Liu, Lei Qiao, Linlin Meng et al.
BACKGROUND: Progression of nontarget lesions (NTLs) after percutaneous coronary intervention (PCI) has been reported. However, it remains unknown whether progression of NTLs was causally related to stenting. This study was undertaken to test the hypothesis that stent implantation triggers acute phas...
Xue-Yi Zhou, Nianhong Wang, Cheng‐Wei Qiu, Liming Luo et al.