Geir Bjørklund, Yuliya Semenova, Lyudmila Pivina, Maryam Dadar et al.
Uranium (U) has no known essential biological functions. Furthermore, it is well known for its toxicity, radioactivity, and carcinogenic potency. Impacts on human health due to U exposure have been studied extensively by many researchers. Chronic exposure to low-level U isotopes (radionuclides) may ...
Geir Bjørklund, Anatoly V. Skalny, Md. Mostafizur Rahman, Maryam Dadar et al.
Autism spectrum disorder (ASD) is a neurodevelopmental disorder characterized by deficits in social interaction, verbal and non‐verbal communication, and stereotypic behaviors. Many studies support a significant relationship between many different environmental factors in ASD etiology. These factors...
Geir Bjørklund, Jan Aaseth, Salvatore Chirumbolo, Mauricio A. Urbina et al.
Worldwide chronic arsenic (As) poisoning by arsenic-contaminated groundwater is one of the most threatening public health problems. Chronic inorganic As (inAs) exposure has been associated with various forms of cancers and numerous other pathological effects in humans, collectively known as arsenico...
Geir Bjørklund, Mostafa I. Waly, Yahya Al‐Farsi, Khaled Saad et al.
Vitamin or mineral supplementation is considered to be the most commonly used medical treatment for autism spectrum disorder (ASD), in addition to other interventions such as neurological and psychological interventions. There is not much evidence of therapeutic efficacy between vitamin and mineral ...
Geir Bjørklund, Alexey A. Tinkov, Maryam Dadar, Md. Mostafizur Rahman et al.
Mercury (Hg), which is a non-essential element, is considered a highly toxic pollutant for biological systems even when present at trace levels. Elevated Hg exposure with the growing release of atmospheric pollutant Hg and rising accumulations of mono-methylmercury (highly neurotoxic) in seafood pro...
Geir Bjørklund, Jan Aaseth, Guido Crisponi, Md. Mostafizur Rahman et al.
Alpha lipoic acid (α-LA) and its reduced form dihydrolipoic acid (DHLA) have been historically considered as excellent anti-oxidants and oxidative stress scavengers. Upon oxidation with reactive oxygen species (ROS) and pro-oxidants, α-LA may be reconstituted from DHLA and other reduced forms. Oxida...
Geir Bjørklund, Lyudmila Pivina, Maryam Dadar, Yuliya Semenova et al.
Indications of proximal tubule effects have been observed in recent surveillance study of Gulf War veterans exposed to depleted uranium (DU). This gives some support for the suspicion that DU may represent one of the causes for the so-called Persian Gulf syndrome. Proposed effects may be especially ...
Geir Bjørklund, Nagwa A. Meguid, Maryam Dadar, Lyudmila Pivina et al.
As a major neurodevelopmental disorder, Autism Spectrum Disorder (ASD) encompasses deficits in communication and repetitive and restricted interests or behaviors in childhood and adolescence. Its etiology may come from either a genetic, epigenetic, neurological, hormonal, or an environmental cause, ...
Geir Bjørklund, Samiul Alam Rajib, Nadia Saffoon, Joeri J. Pen et al.
Along with playing an important role in circadian rhythm, melatonin is thought to play a significant role in preventing cells from damage, as well as in the inhibition of growth and in triggering apoptosis in malignant cells. Its relationship with circadian rhythms, energetic homeostasis, diet, and ...