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Results for “"Hans Wigzell"”

2 results

Downregulation of bactericidal peptides in enteric infections: A novel immune escape mechanism with bacterial DNA as a potential regulator

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Dilara Islam, Lisa Bandholtz, Jakob Nilsson, Hans Wigzell et al.

Journal: Nature MedicineYear: 2001Citations: 424

Antibacterial peptides are active defense components of innate immunity. Several studies confirm their importance at epithelial surfaces as immediate barrier effectors in preventing infection. Here we report that early in Shigella spp. infections, expression of the antibacterial peptides LL-37 and h...

Life SciencesImmunology and MicrobiologyMicrobiology
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An oral B subunit: whole cell vaccine against cholera

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Jan Holmgren, Ann‐Mari Svennerholm, Marianne Jertborn, John D. Clemens et al.

Journal: VaccineYear: 1992Citations: 72

During the last decade there has been a rapid progress in the development of new, much improved vaccines against cholera. These vaccines, which are given orally to stimulate the gut mucosal immune system, are based on either a combination of purified cholera toxin B (binding) subunit and killed chol...

Life SciencesBiochemistry, Genetics and Molecular BiologyEndocrinology
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