Jeanette L. Gehrig, Siddarth Venkatesh, Hao-Wei Chang, Matthew C. Hibberd et al.
To examine the contributions of impaired gut microbial community development to childhood undernutrition, we combined metabolomic and proteomic analyses of plasma samples with metagenomic analyses of fecal samples to characterize the biological state of Bangladeshi children with severe acute malnutr...
Arjun S. Raman, Jeanette L. Gehrig, Siddarth Venkatesh, Hao-Wei Chang et al.
Characterizing the organization of the human gut microbiota is a formidable challenge given the number of possible interactions between its components. Using a statistical approach initially applied to financial markets, we measured temporally conserved covariance among bacterial taxa in the microbi...
Matthew C. Hibberd, Daniel M. Webber, Dmitry A. Rodionov, Suzanne Henrissat et al.
Abstract Evidence is accumulating that perturbed postnatal development of the gut microbiome contributes to childhood malnutrition 1–4 . Here we analyse biospecimens from a randomized, controlled trial of a microbiome-directed complementary food (MDCF-2) that produced superior rates of weight gain c...
Hao-Wei Chang, Evan M. Lee, William Yi Wang, Cyrus Zhou et al.
Microbiota-directed complementary food (MDCF) formulations have been designed to repair the gut communities of malnourished children. A randomized controlled trial demonstrated that one formulation, MDCF-2, improved weight gain in malnourished Bangladeshi children compared to a more calorically dens...
Tuan‐Viet Duong, Wei Hong, Zhang‐Cheng Hao, Weichen Huang et al.
This letter presents an alternative method to realize millimeter wave waveguide diplexers based on high selectivity bandpass filters. A small perturbation is implemented in a dual-mode circular cavity to expand the bandwidth and significantly enhance the selectivity of the channel filter. The locati...
Hao-Wei Chang, Evan M. Lee, William Yi Wang, Cyrus Zhou et al.
Preclinical and clinical studies are providing evidence that the healthy growth of infants and children reflects, in part, healthy development of their gut microbiomes 1–5 . This process of microbial community assembly and functional maturation is perturbed in children with acute malnutrition. Gnoto...
Matthew C. Hibberd, Daniel M. Webber, Dmitry A. Rodionov, Suzanne Henrissat et al.
Evidence is accumulating that perturbed postnatal development of the gut microbiome contributes to childhood malnutrition 1–4 . Designing effective microbiome-directed therapeutic foods to repair these perturbations requires knowledge about how food components interact with the microbiome to alter i...
Guangyao Hao, Weiyi Sun, Jian Liu, Deliang Chen et al.
The Greening of the Sahara (GS) during the African Humid Period (AHP) is a striking example of past climate–vegetation interactions, yet its detailed spatiotemporal patterns across the Holocene remain insufficiently understood. This study develops a data-driven framework that combines paleoclimate s...
Changze Li, Yunxue Lu, Hao Wei, Hao Wang
William Yi Wang, Hao-Wei Chang, Jiye Cheng, Daniel M. Webber et al.
Studies have implicated perturbations in the postnatal development of the gut microbiome as a contributing factor to childhood undernutrition. Compared to a standard ready-to-use supplementary food, a microbiome-directed complementary food (MDCF-2) designed to repair these perturbations produced sup...
Yi Wang, Hao-Wei Chang, Jiye Cheng, Daniel M. Webber et al.
ABSTRACT Studies have implicated perturbations in the postnatal development of the gut microbiome as a contributing factor to childhood undernutrition. Compared to a standard ready-to-use supplementary food, a microbiome-directed complementary food (MDCF-2) designed to repair these perturbations pro...
Aurel von Richthofen, Peng Huiting, Wang Changren, Desirée Ng Zi Qi et al.