Peter Reason, Hilary Bradbury
PART ONE: GROUNDINGS Introduction to Groundings - Peter Reason and Hilary Bradbury Living Inquiry - Patricia Gaya Wicks, Peter Reason and Hilary Bradbury Personal, Political and Philosophical Groundings of Action Research Practice Participatory Action Research as Practice - Marja Liisa Swantz Some T...
Sarah Finer, Hilary C. Martin, Ahsan Khan, Karen A. Hunt et al.
Cohort profile in a nutshell: - East London Genes & Health (ELGH) is a large scale, community genomics and health study (to date >30,000 volunteers; target 100,000 volunteers). - ELGH was set up in 2015 to gain deeper understanding of health and disease, and underlying genetic influences, in people ...
Konstantinos Ν. Fountoulakis, Grigorios N. Karakatsoulis, Seri Abraham, Kristina Adorjan et al.
Introduction There are few published empirical data on the effects of COVID‐19 on mental health, and until now, there is no large international study. Material and methods During the COVID-19 pandemic, an online questionnaire gathered data from 55,589 participants from 40 countries (64.85% females a...
the ARIA Study Group, J. Jean Bousquet, the MASK Study Group, Holger J. Schünemann et al.
BACKGROUND: In all societies, the burden and cost of allergic and chronic respiratory diseases are increasing rapidly. Most economies are struggling to deliver modern health care effectively. There is a need to support the transformation of the health care system into integrated care with organizati...
Laurel Anderson, Jelena Spanjol, Josephine Go Jefferies, Amy L. Ostrom et al.
Responsibilization, or the shift of functions and risks from providers and producers to consumers, has become an increasingly common policy in service systems and marketplaces (e.g., financial, health, governmental). Because responsibilization is often considered synonymous with consumer agency and ...
Qin Qin Huang, Neneh Sallah, Diana Dunca, Bhavi Trivedi et al.
Individuals with South Asian ancestry have a higher risk of heart disease than other groups but have been largely excluded from genetic research. Using data from 22,000 British Pakistani and Bangladeshi individuals with linked electronic health records from the Genes & Health cohort, we conducted ge...
Sam Hodgson, Qin Qin Huang, Neneh Sallah, Chris Griffiths et al.
BACKGROUND: Type 2 diabetes (T2D) is highly prevalent in British South Asians, yet they are underrepresented in research. Genes & Health (G&H) is a large, population study of British Pakistanis and Bangladeshis (BPB) comprising genomic and routine health data. We assessed the extent to which genetic...
Sam Hodgson, Alice Williamson, Margherita Bigossi, Daniel Stow et al.
Abstract South Asians develop type 2 diabetes (T2D) early in life and often with normal body mass index (BMI). However, reasons for this are poorly understood because genetic research is largely focused on European ancestry groups. We used recently derived multi-ancestry partitioned polygenic scores...
Konstantinos Ν. Fountoulakis, Grigorios N. Karakatsoulis, Seri Abraham, Kristina Adorjan et al.
Introduction During the COVID-19 pandemic various degrees of lockdown were applied by countries around the world. It is considered that such measures have an adverse effect on mental health but the relationship of measure intensity with the mental health effect has not been thoroughly studied. Here ...
Benjamin M. Jacobs, Daniel Stow, Sam Hodgson, Julia Zöllner et al.
Abstract Understanding the genetic basis of routinely-acquired blood tests can provide insights into several aspects of human physiology. We report a genome-wide association study of 42 quantitative blood test traits defined using Electronic Healthcare Records (EHRs) of ~50,000 British Bangladeshi a...
Konstantinos Ν. Fountoulakis, Grigorios N. Karakatsoulis, Seri Abraham, Kristina Adorjan et al.
Introduction The current study aimed to investigate the rates of anxiety, clinical depression, and suicidality and their changes in health professionals during the COVID-19 outbreak. Materials and methods The data came from the larger COMET-G study. The study sample includes 12,792 health profession...
Joshua Robert Breedon, Charles R. Marshall, Gavin Giovannoni, David A. van Heel et al.
Abstract Polygenic risk scores aggregate an individual’s burden of risk alleles to estimate the overall genetic risk for a specific trait or disease. Polygenic risk scores derived from genome-wide association studies of European populations perform poorly for other ancestral groups. Given the potent...
Konstantinos Ν. Fountoulakis, Grigorios N. Karakatsoulis, Seri Abraham, Kristina Adorjan et al.
Abstract Background The prevalence of medical illnesses is high among patients with psychiatric disorders. The current study aimed to investigate multi-comorbidity in patients with psychiatric disorders in comparison to the general population. Secondary aims were to investigate factors associated wi...
Qin Qin Huang, Neneh Sallah, Diana Dunca, Bhavi Trivedi et al.
Abstract Background Individuals with South Asian ancestry have higher risk of heart disease than other groups in Western countries; however, most genetic research has focused on European-ancestry (EUR) individuals. It is unknown whether reported genetic loci and polygenic scores (PGSs) for cardiomet...
Nora Bensahel
Click to increase image sizeClick to decrease image size Acknowledgements The author wishes to thank Christopher Chivvis, Jim Dobbins, Rainer Eberle, Tim Martin, Carlos Pascuale, Joanne Pfeiffer, Andrew Rathmell and Benjamin Schreer for their assistance with this project and their comments on previo...