Priti Tagde, Sandeep Tagde, Tanima Bhattacharya, Pooja Tagde et al.
Blockchain and artificial intelligence technologies are novel innovations in healthcare sector. Data on healthcare indices are collected from data published on Web of Sciences and other Google survey from various governing bodies. In this review, we focused on various aspects of blockchain and artif...
Hitesh Chopra, Shabana Bibi, Inderbir Singh, Mohammad Mehedi Hasan et al.
Current advancements in nanotechnology and nanoscience have resulted in new nanomaterials, which may pose health and environmental risks. Furthermore, several researchers are working to optimize ecologically friendly procedures for creating metal and metal oxide nanoparticles. The primary goal is to...
Tanima Bhattacharya, Giselle A. Borges e Soares, Hitesh Chopra, Md. Mominur Rahman et al.
The strategies involved in the development of therapeutics for neurodegenerative disorders are very complex and challenging due to the existence of the blood-brain barrier (BBB), a closely spaced network of blood vessels and endothelial cells that functions to prevent the entry of unwanted substance...
Hitesh Chopra, Protity Shuvra Dey, Debashrita Das, Tanima Bhattacharya et al.
is curcumin and has gained importance in various treatments of various disorders such as antibacterial, antiprotozoal, cancer, obesity, diabetics and wound healing applications. Several techniques had been exploited as reported by researchers for increasing the therapeutic potential and its pharmaco...
Hitesh Chopra, Annu Annu, Dong Kyoo Shin, Kavita Munjal et al.
Clinical trials are the essential assessment for safe, reliable, and effective drug development. Data-related limitations, extensive manual efforts, remote patient monitoring, and the complexity of traditional clinical trials on patients drive the application of Artificial Intelligence (AI) in medic...
Neha Chauhan, Parul Vasava, Sharuk L. Khan, Falak A. Siddiqui et al.
Ethosomal systems are newer lipid vesicular carriers that have been around for 20 years, but over that period they have grown significantly as a means of transdermal drug delivery. They have a sizable amount of ethanol in them. These nanocarriers carry medicinal substances with various physicochemic...
Qamar Sultana, Jill Kar, Amogh Verma, Shreya Sanghvi et al.
Neuroendocrine neoplasms (NENs) are a group of heterogeneous tumors with neuroendocrine differentiation that can arise from any organ. They account for 2% of all malignancies in the United States. A significant proportion of NEN patients experience endocrine imbalances consequent to increased amine ...
S. K. Goel, Ravinder Pal Singh, Varinder Singh, Harmanjit Singh et al.
Metformin is a plant-based drug belonging to the class of biguanides and is known to treat type-2 diabetes mellitus (T2DM). The drug, combined with controlling blood glucose levels, improves the body's response to insulin. In addition, trials have identified the cardioprotective potential of metform...
Rupinder Kaur, Varinder Singh, Pratima Kumari, Ravinder J. Singh et al.
Cell adhesion molecules (CAM) including the intracellular adhesion molecule 1 (ICAM-1) and vascular cell adhesion molecule 1 (VCAM-1) are from the immunoglobulin family which regulates leukocyte adherence to endothelial muscles in acute or chronic inflammatory states [1]. TNF-α, a proinflammatory cy...
Anastasiia D. Shkodina, Shing Cheng Tan, Mohammad Mehedi Hasan, Mai Abdelgawad et al.
Parkinson's disease (PD) is a common motor disorder that has become increasingly prevalent in the ageing population. Recent works have suggested that circadian rhythms disruption is a common event in PD patients. Clock genes regulate the circadian rhythm of biological processes in eukaryotic organis...
Inderbir Singh, Md. Habibur Rahman, Hitesh Chopra, Sandeep Kumar et al.
The conventional drug delivery systems have a long list of repeated dosing and toxicity issues. The hydrogels solve these issues as they minimize such activities and optimize therapeutic benefits. The hydrogels possess tunable properties that can withstand degradation, metabolism, and control releas...
Dmytro I. Boiko, Anastasiia D. Shkodina, Mohammad Mehedi Hasan, Mainak Bardhan et al.
A complex pathogenesis involving several physiological systems is theorized to underline the development of depressive disorders. Depression is accompanied by circadian regulation disruption and interaction with the functioning of both central and peripheral oscillators. Many aspects of melatonin fu...
Rajeev K. Singla, Ronita De, Thomas Efferth, Bruno Mezzetti et al.
BACKGROUND: The development of digital technologies and the evolution of open innovation approaches have enabled the creation of diverse virtual organizations and enterprises coordinating their activities primarily online. The open innovation platform titled "International Natural Product Sciences T...
Hitesh Chopra, Shabana Bibi, Awdhesh Kumar Mishra, Vineet Tirth et al.
Cardiovascular diseases (CVDs) are a primary cause of death globally. A few classic and hybrid treatments exist to treat CVDs. However, they lack in both safety and effectiveness. Thus, innovative nanomaterials for disease diagnosis and treatment are urgently required. The tiny size of nanomaterials...
Harsh Kumar, Navidha Aggarwal, Minakshi Gupta Marwaha, Aakash Deep et al.
Heterocyclic compounds containing nitrogen and sulfur, especially those in the thiazole family, have generated special interest in terms of their synthetic chemistry, which is attributable to their ubiquitous existence in pharmacologically dynamic natural products and also as overwhelmingly powerful...