Md Shahed Morshed, Hurjahan Banu, Nazma Akhtar, Tania Sultana et al.
Background: Altered luteinizing hormone to follicle-stimulating hormone (LH-FSH) ratio and hyperandrogenism are two important pathophysiological characteristics of polycystic ovary syndrome (PCOS). The aim of this study was to evaluate the relationship of LH-FSH ratio with androgen in women with PCO...
Mst. Noorjahan Begum, Md Tarikul Islam, Shekh Rezwan Hossain, Golam Sarower Bhuyan et al.
Although thyroid dyshormonogenesis (TDH) accounts for 10-20% of congenital hypothyroidism (CH), the molecular etiology of TDH is unknown in Bangladesh. Thyroid peroxidase (TPO) is most frequently associated with TDH and the present study investigated the spectrum of TPO mutations in Bangladeshi pati...
Hurjahan Banu, Md Shahed Morshed, Tania Sultana, Sukanti Shah et al.
Background: ). Aim: This study was aimed to see the magnitude of associations of VAI and LAP with cardiometabolic risk factors including IR and MetS in lean PCOS. Study Setting and Design: This cross-sectional study was done amongst 62 newly detected lean PCOS patients and 58 age- and BMI-matched he...
Marufa Mustari, MA Hasanat, Q. Z. Hasan, Sadiqa Tuqan et al.
Polycystic ovarian syndrome (PCOS) is a common disorder for female with fertile age. Along with other clinical and biochemical manifestations, thyroid function and prolactin level may be altered in patients with PCOS. This study aimed to evaluate the clinical and biochemical status, as well as alter...
Hurjahan Banu, Nusrat Sultana, Md Shahed Morshed, Muhammad Abul Hasanat et al.
Objectives: This study determined the baseline hypothalamic-pituitary-adrenal axis hormonal levels and their associated factors in noncritically ill hospitalized patients with coronavirus disease 2019 (COVID-19). Methodology: This cross-sectional study was carried out in 91 noncritical RT-PCR-confir...
Sukanti Shah, Hurjahan Banu, Tania Sultana, Nazma Akhtar et al.
Background: Androgen excess may correlate with metabolic risk in polycystic ovary syndrome (PCOS). The aim of the study was to determine the role of total testosterone to dihydrotestosterone (TT/DHT) ratio in assessing the adverse metabolic outcome in PCOS. Methods: This cross-sectional study encomp...
Tahmina Ferdousi, Hurjahan Banu, Nusrat Sultana, Hafsa Mahrukh et al.
Turner syndrome (TS) is the most common cause of short stature and delayed puberty in females. Approximately half of the patients have the classic form with a genotype of 45,XO, one-fourth of patients have different mosaic forms, and the remaining one-fourth have structural abnormalities on the X ch...
Begum Moriom Zamila, Hurjahan Banu, Md Shahed Morshed, Sukanti Shah et al.
Background: Menstrual irregularities may predict over adverse consequences in polycystic ovary syndrome (PCOS).Objective: To observe the relation of variants of menstrual cycles with clinical and biochemical features of PCOS.Methods: This cross-sectional study encompassed 200 PCOS women diagnosed by...
Tania Tofail, Mohammed Fariduddin, Tahniyah Haq, Shahjada Selim et al.
Objective: Medullary thyroid carcinomas (MTCs) originate from parafollicular C cells and produce the hormone calcitonin, which is primarily responsible for the biochemical dysfunction in calcium metabolism seen in MTC. MTCs constitute only about 5 to 7% of thyroid neoplasms. In rare cases, serum cal...
Mashfiqul Hasan, Md. Shahed Morshed, Tania Tofail, Nusrat Sultana et al.
Objective: Early-onset type 2 diabetes (T2D) is an emerging public health concern. Despite its rising burden, national data on the prevalence and risk factors in Bangladesh remain scarce. This study aimed to estimate the prevalence of early-onset T2D and identify risk factors among young people in B...
Choman Abdullah Mohana, M A Hasanat, Emran Ur Rashid, Iffat Jahan et al.
Background: Polycystic ovary syndrome (PCOS) is a common endocrine problem and increasing worldwide. Dysregulated adipocytokine production is thought to be linked with pathogenesis of PCOS.Objective: The aim of this study was to see the relation of leptin, adiponectin and their ratio with PCOS and i...
Mst. Noorjahan Begum, Rumana Mahtarin, Md Tarikul Islam, Nusrat Jahan Antora et al.
TPO (Thyroid Peroxidase) is known to be one of the major genes involved in congenital hypothyroid patients with thyroid dyshormonogenesis. The present study aims to validate high-resolution melting (HRM) curve analysis as a substitute method for Sanger sequencing, focusing on the frequently observed...
Nazma Akhtar, Muhammad Abul Hasanat, Sadiqa Tuqan, Md Fariduddin et al.
Background: Polycystic ovary syndrome (PCOS) is a heterogeneous endocrine disorder affecting women of reproductive age. Treatment by metformin is based on the basis of insulin resistance in PCOS.
Md Fariduddin, A. K. M. Aminul Islam, Md Abu Jar Gaffar, Murshed Ahamed Khan et al.
Background: Most of the people with uncomplicated type 2 diabetes mellitus (T2DM) fast during the holy month of Ramadan in Bangladesh. Safe Ramadan fasting is a great challenge for both physician and people with diabetes. Objectives: This study was conducted to observe the effects of Ramadan-focused...
Emran-Ur-Rashid Chowdhury, Hurjahan Banu, Md Shahed Morshed, Iffat Ara Jahan et al.
Background. Bisphenol A (BPA) is a widely used industrial element. Recently it is suspected that BPA may disrupt the endocrine system to influence the manifestations of polycystic ovary syndrome (PCOS). Objective. This study aimed to assess serum BPA level and its association with manifestations of ...
Zinia Haidar, Hurjahan Banu, Md Shahed Morshed, Sharif Akhteruzzaman et al.
Shazia Afrine, Jasmine Ara Haque, Md Shahed Morshed, Hurjahan Banu et al.
OBJECTIVE: Polycystic ovary (PCO), a diagnostic component of polycystic ovary syndrome (PCOS), requires either an ovarian volume (OV) criterion or a follicle number per ovary (FNPO) criterion. This study investigated the association of OV and FNPO criteria with various manifestations of PCOS. METHOD...
Hurjahan Banu, Md Shahed Morshed, Sadiqa Tuqan, Nazma Akhtar et al.
Antimullarian hormone (AMH) is found to be a vital tool for the diagnosis of polycystic ovary syndrome (PCOS). AMH may help in the diagnosis of sonographically inconclusive cases of PCOS. This study measured the AMH level in PCOS to assess its impacts on the diagnosis of the syndrome. This cross-sec...
Nazma Akhtar, Hurjahan Banu, Md Shahed Morshed, Tania Sultana et al.
Background and objectives: Metformin improves manifestations of polycystic ovary syndrome (PCOS) by reducing insulin resistance. The objective of this study was to determine how metformin, in combination with lifestyle changes, affects the clinical manifestations of PCOS.
 Materials and Methods...
Md Shahed Morshed, Hurjahan Banu, Nazma Akhtar, Tania Sultana et al.
Background: Altered luteinizing hormone to follicle-stimulating hormone (LH-FSH) ratio and hyperandrogenism are two important pathophysiological characteristics of polycystic ovary syndrome (PCOS). The aim of this study was to evaluate the relationship of LH-FSH ratio with androgen in women with PCO...