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Results for “"Ian J. Alexander"”

16+ results

Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition)<sup>1</sup>

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Daniel J. Klionsky, Amal Kamal Abdel‐Aziz, Sara Abdelfatah, Mahmoud Abdellatif et al.

Journal: AutophagyYear: 2021Citations: 2602

autophagic responses. Here, we critically discuss current methods of assessing autophagy and the information they can, or cannot, provide. Our ultimate goal is to encourage intellectual and technical innovation in the field.

Health SciencesMedicineEpidemiologyOpen Access
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A Strategy To Estimate Unknown Viral Diversity in Mammals

Verified

Simon J. Anthony, Jonathan H. Epstein, Kris A. Murray, Isamara Navarrete‐Macias et al.

Journal: mBioYear: 2013Citations: 424

UNLABELLED: The majority of emerging zoonoses originate in wildlife, and many are caused by viruses. However, there are no rigorous estimates of total viral diversity (here termed "virodiversity") for any wildlife species, despite the utility of this to future surveillance and control of emerging zo...

Health SciencesMedicinePublic Health, Environmental and Occupational HealthOpen Access
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Genome-wide association meta-analysis of human longevity identifies a novel locus conferring survival beyond 90 years of age

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Joris Deelen, Marian Beekman, Hae‐Won Uh, Linda Broer et al.

Journal: Human Molecular GeneticsYear: 2014Citations: 271

The genetic contribution to the variation in human lifespan is ∼ 25%. Despite the large number of identified disease-susceptibility loci, it is not known which loci influence population mortality. We performed a genome-wide association meta-analysis of 7729 long-lived individuals of European descent...

Life SciencesBiochemistry, Genetics and Molecular BiologyGeneticsOpen Access
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Non-random patterns in viral diversity

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Simon J. Anthony, Ariful Islam, Christine K. Johnson, Isamara Navarrete‐Macias et al.

Journal: Nature CommunicationsYear: 2015Citations: 84

It is currently unclear whether changes in viral communities will ever be predictable. Here we investigate whether viral communities in wildlife are inherently structured (inferring predictability) by looking at whether communities are assembled through deterministic (often predictable) or stochasti...

Health SciencesMedicinePublic Health, Environmental and Occupational HealthOpen Access
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A multi-taxon analysis of European Red Lists reveals major threats to biodiversity

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Axel Hochkirch, Melanie Bilz, Catarina Ferreira, Anja Danielczak et al.

Journal: PLoS ONEYear: 2023Citations: 75

Biodiversity loss is a major global challenge and minimizing extinction rates is the goal of several multilateral environmental agreements. Policy decisions require comprehensive, spatially explicit information on species' distributions and threats. We present an analysis of the conservation status ...

Physical SciencesEnvironmental ScienceGlobal and Planetary ChangeOpen Access
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Breaking ground in cross-cultural research on the fear of being laughed at (gelotophobia): A multi-national study involving 73 countries

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René T. Proyer, Willibald Ruch, Numan Ali, Hmoud Al-Olimat et al.

Journal: Humor - International Journal of Humor ResearchYear: 2009Citations: 71

Abstract The current study examines whether the fear of being laughed at (gelotophobia) can be assessed reliably and validly by means of a self-report instrument in different countries of the world. All items of the GELOPH (Ruch and Titze, GELOPH〈46〉, University of Düsseldorf, 1998; Ruch and Proyer,...

Social SciencesPsychologySocial PsychologyOpen Access
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Ectomycorrhizas – out of Africa?

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Ian J. Alexander

Journal: New PhytologistYear: 2006Citations: 54

Ectomycorrhizas are the most frequent and widespread mycorrhizal type in the forests and woodlands of cool-temperate and boreal latitudes. Tree species from all the major plant families that provide the dominant trees of these regions (e.g. Pinaceae, Fagaceae, Betulaceae, Salicaceae) habitually form...

Life SciencesAgricultural and Biological SciencesPlant ScienceOpen Access
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Long‐Distance Avian Migrants Fail to Bring 2.3.4.4b HPAI H5N1 Into Australia for a Second Year in a Row

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Michelle Wille, Robyn Atkinson, Ian Barr, Charlotte Burgoyne et al.

Journal: Influenza and Other Respiratory VirusesYear: 2024Citations: 29

The current high-pathogenicity avian influenza (HPAI) H5N1 lineage 2.3.4.4b panzootic is having a profound impact on the poultry industry and wildlife [1, 2]. HPAI H5N1 emerged in poultry in 1996 and has caused outbreaks in wild bird populations episodically since 2005 [3], with the epidemiology of ...

Social SciencesSociology and Political ScienceClimate Change, Adaptation, MigrationOpen Access
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Effect of Superphosphate and Arbuscular Mycorrhizal Fungus Glomus mosseae on Phosphorus and Arsenic Uptake in Lentil (Lens culinaris L.)

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Fazel R. Sadeque Ahmed, Ian J. Alexander, Mwinyikione Mwinyihija, K. Killham

Journal: Water Air & Soil PollutionYear: 2011Citations: 20
Life SciencesAgricultural and Biological SciencesPlant Science
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Retinal microvascular parameters are not significantly associated with mild cognitive impairment in the Northern Ireland Cohort for the Longitudinal Study of Ageing

Verified

R. A. O’Neill, Alexander P. Maxwell, Euan Paterson, Frank Kee et al.

Journal: BMC NeurologyYear: 2021Citations: 18

BACKGROUND: The retinal and cerebral microvasculature share similar embryological origins and physiological characteristics. Improved imaging technologies provide opportunistic non-invasive assessment of retinal microvascular parameters (RMPs) against cognitive outcomes. We evaluated baseline measur...

Health SciencesMedicineRadiology, Nuclear Medicine and ImagingOpen Access
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Association of retinal venular tortuosity with impaired renal function in the Northern Ireland Cohort for the Longitudinal Study of Ageing

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R. A. O’Neill, Alexander P. Maxwell, Frank Kee, Ian Young et al.

Journal: BMC NephrologyYear: 2020Citations: 18

Abstract Background Previous studies have identified retinal microvascular features associated with renal dysfunction. Biopsies are necessary to confirm kidney microvascular damage and retinal imaging may enable evaluation of microangiopathic characteristics reflecting renal changes associated with ...

Health SciencesMedicineRadiology, Nuclear Medicine and ImagingOpen Access
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Experiences of renal healthcare practitioners during the COVID-19 pandemic: a multi-methods approach

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Clare Mc Keaveney, Joanne Reid, Claire Carswell, Ann Bonner et al.

Journal: BMC NephrologyYear: 2021Citations: 13

BACKGROUND: Globally, renal healthcare practitioners provide intensive and protracted support to a highly complex multi-morbid patient population however knowledge about the impact of COVID-19 on these practitioners is extremely limited. OBJECTIVE: This study aimed to explore the experiences of COVI...

Social SciencesPsychologyClinical PsychologyOpen Access
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The Limits of the human security agenda: the case of Canada's response to the Timor crisis

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T.S. Hataley, Kim Richard Nossal

Journal: Global Change Peace & SecurityYear: 2004Citations: 12

Abstract Enthusiasts of human security argue that what is needed in the post‐Cold‐War period is a foreign policy agenda that is more ‘people‐centred’ than the state‐centred focus of security policy during the Cold War period. Among the most enthusiastic proponents of the human security paradigm in t...

Social SciencesPolitical Science and International RelationsGlobal Peace and Security Dynamics
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Association of reduced retinal arteriolar tortuosity with depression in older participants from the Northern Ireland Cohort for the Longitudinal Study of Ageing

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R. A. O’Neill, Alexander P. Maxwell, Frank Kee, Ian Young et al.

Journal: BMC GeriatricsYear: 2021Citations: 10

INTRODUCTION: The retina shares similar anatomical and physiological features with the brain and subtle variations in retinal microvascular parameters (RMPs) may reflect similar vascular variation in the brain. The aim of this study was to assess associations between RMPs and measures of depression ...

Health SciencesMedicineRadiology, Nuclear Medicine and ImagingOpen Access
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Gender equality and quality of life must be central to the design and delivery of sanitation

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Akanksha A. Marphatia, Sheillah Simiyu, MJ O'Kane, Kelly Alexander et al.

Journal: BMJ Global HealthYear: 2025Citations: 6

Summary box Sanitation is critical to improving quality of life and gender equality.

Health SciencesNursingNutrition and DieteticsOpen Access
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