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Results for “"Ishaq Khan"”

16+ results

Phytol: A review of biomedical activities

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Muhammad Torequl Islam, Eunüs S. Ali, Shaikh Jamal Uddin, Subrata Shaw et al.

Journal: Food and Chemical ToxicologyYear: 2018Citations: 459

Phytol (PYT) is a diterpene member of the long-chain unsaturated acyclic alcohols. PYT and some of its derivatives, including phytanic acid (PA), exert a wide range of biological effects. PYT is a valuable essential oil (EO) used as a fragrance and a potential candidate for a broad range of applicat...

Life SciencesBiochemistry, Genetics and Molecular BiologyMolecular BiologyOpen Access
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Berberine as a Potential Anticancer Agent: A Comprehensive Review

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Abdur Rauf, Tareq Abu‐Izneid, Anees Ahmed Khalil, Muhammad Imran et al.

Journal: MoleculesYear: 2021Citations: 283

Berberine (BBR), a potential bioactive agent, has remarkable health benefits. A substantial amount of research has been conducted to date to establish the anticancer potential of BBR. The present review consolidates salient information concerning the promising anticancer activity of this compound. T...

Health SciencesMedicinePharmacologyOpen Access
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Protective and therapeutic potential of ginger (<scp><i>Zingiber officinale</i></scp>) extract and [6]‐gingerol in cancer: A comprehensive review

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Rosália Maria Tôrres de Lima, Antonielly Campinho dos Reis, Ag‐Anne Pereira Melo de Menezes, José Victor de Oliveira Santos et al.

Journal: Phytotherapy ResearchYear: 2018Citations: 263

Natural dietary agents have attracted considerable attention due to their role in promoting health and reducing the risk of diseases including cancer. Ginger, one of the most ancient known spices, contains bioactive compounds with several health benefits. [6]-Gingerol constitutes the most pharmacolo...

Life SciencesPharmacology, Toxicology and PharmaceuticsPharmacology
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Targeting cancer cells with nanotherapeutics and nanodiagnostics: Current status and future perspectives

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Eunüs S. Ali, Shazid Md. Sharker, Muhammad Torequl Islam, Ishaq Khan et al.

Journal: Seminars in Cancer BiologyYear: 2020Citations: 260

Nanotechnology is reshaping health care strategies and is expected to exert a tremendous impact in the coming years offering better healthcare facilities. It has led to not only therapeutic drug delivery feasibility but also to diagnostics. Materials in the size of nano range (1-100 mm) used in the ...

Physical SciencesMaterials ScienceBiomaterials
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Recent advances and limitations of mTOR inhibitors in the treatment of cancer

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Eunüs S. Ali, Kangkana Mitra, Shamima Akter, Sarker Ramproshad et al.

Journal: Cancer Cell InternationalYear: 2022Citations: 207

The PI3K-Akt-mechanistic (formerly mammalian) target of the rapamycin (mTOR) signaling pathway is important in a variety of biological activities, including cellular proliferation, survival, metabolism, autophagy, and immunity. Abnormal PI3K-Akt-mTOR signalling activation can promote transformation ...

Life SciencesBiochemistry, Genetics and Molecular BiologyMolecular BiologyOpen Access
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Andrographolide, a diterpene lactone from Andrographis paniculata and its therapeutic promises in cancer

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Muhammad Torequl Islam, Eunüs S. Ali, Shaikh Jamal Uddin, Md. Amirul Islam et al.

Journal: Cancer LettersYear: 2018Citations: 206

The diterpene lactone andrographolide, isolated from Andrographis paniculata, has been proven to possess several important protective biological activities, including antioxidant, anti-inflammatory, immunomodulatory, antiseptic, antimicrobial, cytotoxic, hypolipidemic, cardioprotective, hepatoprotec...

Health SciencesMedicineComplementary and alternative medicine
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Application of CSM-CROPGRO-Cotton model for cultivars and optimum planting dates: Evaluation in changing semi-arid climate

Verified

Muhammad Habib ur Rahman, Ashfaq Ahmad, Aftab Wajid, Manzoor Hussain et al.

Journal: Field Crops ResearchYear: 2017Citations: 104

Simulation models are widely used for making decision support especially under sub-optimal climatic conditions for yield improvement. The impact of uncertain weather conditions on cotton production can be explored with the aid of such models. Cotton, being the queen of fibers, enjoys itself a predom...

Life SciencesAgricultural and Biological SciencesPlant Science
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Biochar and urease inhibitor mitigate NH3 and N2O emissions and improve wheat yield in a urea fertilized alkaline soil

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Khadim Dawar, Shah Fahad, M. M. R. Jahangir, Iqbal Munir et al.

Journal: Scientific ReportsYear: 2021Citations: 84

Abstract In this study, we explored the role of biochar (BC) and/or urease inhibitor (UI) in mitigating ammonia (NH 3 ) and nitrous oxide (N 2 O) discharge from urea fertilized wheat cultivated fields in Pakistan (34.01°N, 71.71°E). The experiment included five treatments [control, urea (150 kg N ha...

Life SciencesAgricultural and Biological SciencesSoil ScienceOpen Access
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Exogenous Sodium Nitroprusside Mitigates Salt Stress in Lentil (Lens culinaris Medik.) by Affecting the Growth, Yield, and Biochemical Properties

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Tauqeer Ahmad Yasir, Ayesha Khan, Milan Skalický, Allah Wasaya et al.

Journal: MoleculesYear: 2021Citations: 73

Soil salinity disrupts the physiological and biochemical processes of crop plants and ultimately leads to compromising future food security. Sodium nitroprusside (SNP), a contributor to nitric oxide (NO), holds the potential to alleviate abiotic stress effects and boost tolerance in plants, whereas ...

Life SciencesAgricultural and Biological SciencesPlant ScienceOpen Access
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Role of Withaferin A and Its Derivatives in the Management of Alzheimer’s Disease: Recent Trends and Future Perspectives

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Rajib Das, Abdur Rauf, Saima Akhter, Mohammad Nazmul Islam et al.

Journal: MoleculesYear: 2021Citations: 67

Globally, Alzheimer’s disease (AD) is one of the most prevalent age-related neurodegenerative disorders associated with cognitive decline and memory deficits due to beta-amyloid deposition (Aβ) and tau protein hyperphosphorylation. To date, approximately 47 million people worldwide have AD. This fig...

Health SciencesMedicineComplementary and alternative medicineOpen Access
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A Perspective on Emerging Therapeutic Interventions for COVID-19

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Muhammad Torequl Islam, Md. Nasiruddin, Ishaq Khan, S. Mishra et al.

Journal: Frontiers in Public HealthYear: 2020Citations: 65

Coronaviruses (CoVs) are enveloped positive-sense RNA viruses with an unusually large RNA genome, and a unique replication strategy, and are characterized by club-like spikes that project from their surface. An outbreak of a novel coronavirus 2019 (nCoV-2019) infection has posed significant threat t...

Health SciencesMedicineInfectious DiseasesOpen Access
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High-Resolution Intertidal Topography from Sentinel-2 Multi-Spectral Imagery: Synergy between Remote Sensing and Numerical Modeling

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Md Jamal Uddin Khan, Md. Nazmuddoha Ansary, Fabien Durand, Laurent Testut et al.

Journal: Remote SensingYear: 2019Citations: 58

The intertidal zones are well recognized for their dynamic nature and role in near-shore hydrodynamics. The intertidal topography is poorly mapped worldwide due to the high cost of associated field campaigns. Here we present a combination of remote-sensing and hydrodynamic modeling to overcome the l...

Physical SciencesEarth and Planetary SciencesEarth-Surface ProcessesOpen Access
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A systematic review on antioxidant and antiinflammatory activity of Sesame (<scp><i>Sesamum indicum</i></scp> L.) oil and further confirmation of antiinflammatory activity by chemical profiling and molecular docking

Verified

Mohasana Afroz, S. M. Neamul Kabir Zihad, Shaikh Jamal Uddin, Razina Rouf et al.

Journal: Phytotherapy ResearchYear: 2019Citations: 56

Traditionally, sesame oil (SO) has been used as a popular food and medicine. The review aims to summarize the antioxidant and antiinflammatory effects of SO and its identified compounds as well as further fatty acid profiling and molecular docking study to correlate the interaction of its identified...

Life SciencesAgricultural and Biological SciencesPlant ScienceOpen Access
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Anticancer effects of acteoside: Mechanistic insights and therapeutic status

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Rasel Ahmed Khan, Rajib Hossain, Pranta Roy, Divya Jain et al.

Journal: European Journal of PharmacologyYear: 2021Citations: 53

Cancer, the uncontrolled proliferation and metastasis of abnormal cells, is a major public health issue worldwide. To date, several natural compounds have been reported with their efficacy in the treatment of different types of cancer. Chemotherapeutic agents are used in cancer treatment and prevent...

Life SciencesAgricultural and Biological SciencesPlant Science
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Targeting Ras-ERK cascade by bioactive natural products for potential treatment of cancer: an updated overview

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Eunüs S. Ali, Shamima Akter, Sarker Ramproshad, Banani Mondal et al.

Journal: Cancer Cell InternationalYear: 2022Citations: 50

MAPK (mitogen-activated protein kinase) or ERK (extracellular-signal-regulated kinase) pathway is an important link in the transition from extracellular signals to intracellular responses. Because of genetic and epigenetic changes, signaling cascades are altered in a variety of diseases, including c...

Health SciencesMedicinePharmacologyOpen Access
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