Jérôme H. Kim, Florian Marks, John D Clemens
After the recent announcement of COVID-19 vaccine efficacy in clinical trials by several manufacturers for protection against severe disease, a comprehensive post-efficacy strategy for the next steps to ensure vaccination of the global population is now required. These considerations should include ...
Nicos Karasavvas, Erik Billings, Mangala Rao, Constance Williams et al.
The Thai Phase III clinical trial (RV144) showed modest efficacy in preventing HIV-1 acquisition. Plasma collected from HIV-1-uninfected trial participants completing all injections with ALVAC-HIV (vCP1521) prime and AIDSVAX B/E boost were tested for antibody responses against HIV-1 gp120 envelope (...
Xiaodong Zhou, Giovanni Targher, Christopher D. Byrne, Virend K. Somers et al.
Background Fatty liver disease in the absence of excessive alcohol consumption is an increasingly common condition with a global prevalence of ~ 25–30% and is also associated with cardiovascular disease (CVD). Since systemic metabolic dysfunction underlies its pathogenesis, the term metabolic (dysfu...
Gong Feng, Giovanni Targher, Christopher D. Byrne, Yusuf Yılmaz et al.
Background & Aims: This study used the Global Burden of Disease data (2010-2021) to analyze the rates and trends of point prevalence, annual incidence, and years lived with disability (YLDs) for metabolic dysfunction-associated steatotic liver disease (MASLD) in 204 countries. Methods: Total numbers...
Alexander van Geen, K. A. Radloff, Z. Aziz, Zhongqi Cheng et al.
One of the reasons the processes resulting in As release to groundwater in southern Asia remain poorly understood is the high degree of spatial variability of physical and chemical properties in shallow aquifers. In an attempt to overcome this difficulty, a simple device that collects groundwater an...
Min Seo Kim, Se Yong Jung, Jong Gyun Ahn, Se-Jin Park et al.
Two messenger RNA (mRNA) vaccines developed by Pfizer-BioNTech and Moderna are being rolled out. Despite the high volume of emerging evidence regarding adverse events (AEs) associated with the COVID-19 mRNA vaccines, previous studies have thus far been largely based on the comparison between vaccina...
Justin Im, Ruchita Balasubramanian, Moussa Ouédraogo, Lady Rosny Wandji Nana et al.
BACKGROUND: Dengue is prevalent in as many as 128 countries with more than 100 million clinical episodes reported annually and four billion people estimated to be at risk. While dengue fever is systematically diagnosed in large parts of Asia and South America, the disease burden in Africa is less we...
Silvia E. Arranz, Jean‐Christophe Avarre, Chellam Balasundaram, Carmen Bouza et al.
Abstract This article documents the addition of 268 microsatellite marker loci to the M olecular E cology R esources D atabase. Loci were developed for the following species: A lburnoides bipunctatus, C hamaerops humilis, C hlidonias hybrida, C yperus papyrus, F usarium graminearum, L oxigilla barba...
Joacim Rocklöv, Jan C. Semenza, Shouro Dasgupta, Elizabeth Robinson et al.
Climate change is one of several drivers of recurrent outbreaks and geographical range expansion of infectious diseases in Europe. We propose a framework for the co-production of policy-relevant indicators and decision-support tools that track past, present, and future climate-induced disease risks ...
Nittaya Phanuphak, Ying-Ru Lo, Yiming Shao, Sunil S. Solomon et al.
An overall decrease of HIV prevalence is now observed in several key Asian countries due to effective prevention programs. The decrease in HIV prevalence and incidence may further improve with the scale-up of combination prevention interventions. The implementation of future prevention trials then f...
Mohammad Ali, Firdausi Qadri, Deok Ryun Kim, Md Taufiqul Islam et al.
BACKGROUND: Killed whole-cell oral cholera vaccines (OCVs) are widely used for prevention of cholera in developing countries. However, few studies have evaluated the protection conferred by internationally recommended OCVs for durations beyond 2 years of follow-up. METHODS: In this study, we followe...
Justin Im, Md Taufiqul Islam, Faisal Ahmmed, Deok Ryun Kim et al.
BACKGROUND: Sustained investments in water, sanitation, and hygiene (WASH) have lagged in resource-poor settings; incremental WASH improvements may, nonetheless, prevent diseases such as typhoid in disease-endemic populations. METHODS: Using prospective data from a large cohort in urban Kolkata, Ind...
Trevor Toy, Gi Deok Pak, Trung Pham Duc, James I. Campbell et al.
BACKGROUND: Antimicrobial resistance (AMR) is a major global health concern, yet, there are noticeable gaps in AMR surveillance data in regions such as sub-Saharan Africa. We aimed to measure the prevalence of extended-spectrum β-lactamase (ESBL) producing Gram-negative bacteria in bloodstream infec...
Birkneh Tilahun Tadesse, Farhana Khanam, Faisal Ahmmed, Justin Im et al.
BACKGROUND: Typhoid fever contributes to approximately 135 000 deaths annually. Achievable improvements in household water, sanitation, and hygiene (WASH) combined with vaccination using typhoid conjugate vaccines (TCVs) may be an effective preventive strategy. However, little is known about how imp...
Hyon Jin Jeon, Gi Deok Pak, Justin Im, Ellis Owusu‐Dabo et al.
Background: The World Health Organization recently prequalified a typhoid conjugate vaccine (TCV), recommending its use in persons ≥6 months to 45 years residing in typhoid fever (TF)-endemic areas. We now need to consider how TCVs can have the greatest impact in the most vulnerable populations. Met...