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Results for “"Jacqueline Cronin"”

2 results

Remdesivir (GS-5734) protects African green monkeys from Nipah virus challenge

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Michael K. Lo, Friederike Feldmann, Joy Gary, Robert Jordan et al.

Journal: Science Translational MedicineYear: 2019Citations: 273

spp. fruit bats, to humans, it causes respiratory and neurological disease with a case-fatality rate about 70%. Human-to-human transmission has been observed during Nipah virus outbreaks in Bangladesh and India. A therapeutic treatment for Nipah virus disease is urgently needed. Here, we tested the ...

Health SciencesMedicineEpidemiologyOpen Access
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Distinct VSV-based Nipah virus vaccines expressing either glycoprotein G or fusion protein F provide homologous and heterologous protection in a nonhuman primate model

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Emmie de Wit, Friederike Feldmann, Jacqueline Cronin, Kerry Goldin et al.

Journal: EBioMedicineYear: 2022Citations: 27

BACKGROUND: Nipah virus (NiV) causes recurrent outbreaks of lethal respiratory and neurological disease in Southeast Asia. The World Health Organization considers the development of an effective vaccine against NiV a priority. METHODS: We produced two NiV vaccine candidates using the licensed VSV-EB...

Health SciencesMedicineEpidemiologyOpen Access
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