Dayana A. Delgado, Chenan Zhang, Lin Chen, Jianjun Gao et al.
Background Leucocyte telomere length (TL) is a potential biomarker of ageing and risk for age-related disease. Leucocyte TL is heritable and shows substantial differences by race/ethnicity. Recent genome-wide association studies (GWAS) report ~10 loci harbouring SNPs associated with leucocyte TL, bu...
Jianjun Gao, Shantanu Roy, Tong Lin, Maria Argos et al.
Background Inorganic arsenic is a carcinogen whose mode of action may involve telomere dysfunction. Recent epidemiological studies suggest that chronic arsenic exposure is associated with longer telomeres and altered expression of telomere-related genes in peripheral blood. In this study, we evaluat...
Sijie Ge, Heng Gao, Ruijiang Hong, Jianjun Li et al.
(CZTSSe) solar cells based on dimethyl sulfoxide (DMSO) Cu-Zn-Sn-S precursor ink have seen tremendous progress in recent years. However, the wettability between the ink and Mo substrate is poor, owing to the high viscosity of the highly concentrated Cu-Zn-Sn-S ink. Herein, a solvent engineering proc...
Dayana A. Delgado, Chenan Zhang, Kevin J. Gleason, Kathryn Demanelis et al.
Leukocyte telomere length (LTL) is a heritable trait with two potential sources of heritability (h2): inherited variation in non-telomeric regions (e.g., SNPs that influence telomere maintenance) and variability in the lengths of telomeres in gametes that produce offspring zygotes (i.e., “direct” in...
Chenan Zhang, Muhammad G. Kibriya, Farzana Jasmine, Shantanu Roy et al.
Background: Chronic arsenic exposure is associated with increased risk for arsenical skin lesions, cancer, and other adverse health outcomes. One potential mechanism of arsenic toxicity is telomere dysfunction. However, prior epidemiological studies of arsenic exposure, telomere length (TL), and ski...
Jianjun Gao, Tong Lin, Maria Argos, Molly Scannell Bryan et al.
BACKGROUND: Consumption of arsenic-contaminated drinking water adversely affects health. There is interindividual variation in arsenic metabolism efficiency, partially due to genetic variation in the arsenic methyltransferase (AS3MT) gene region. OBJECTIVES: The goal of this study was to assess the ...
Samantha G. Dean, Chenan Zhang, Jianjun Gao, Shantanu Roy et al.
Telomeres are tandem repeat sequences at the end of chromosomes that bind proteins to protect chromosome ends. Telomeres shorten with age, and shorter leukocyte telomere length (TL) has been associated with overall mortality in numerous studies. However, this association has not been tested in popul...
Jianjun Gao
Shumei Miao, Pei Ji, Yongqian Zhu, Haoyu Meng et al.
Background: Due to the acceleration of the aging population and the prevalence of unhealthy lifestyles, the incidence of cardiovascular diseases (CVDs) in China continues to grow. However, due to the uneven distribution of medical resources across regions and significant disparities in diagnostic an...
Dayana A. Delgado, Chenan Zhang, Kathryn Demanelis, Lin Chen et al.
ABSTRACT Leukocyte telomere length (LTL) is a heritable trait with two potential sources of heritability (h 2 ): inherited variation in non-telomeric regions (e.g., SNPs that influence telomere maintenance) and variability in the lengths of telomeres in gametes that produce offspring zygotes (i.e., ...
Vesna Slavkovich, Ronald Rahaman, Golam Sarwar, Habibul Ahsan et al.
Inorganic arsenic is a carcinogen whose mode of action may involve telomere dysfunction. Recent epidemiological studies suggest that chronic arsenic exposure is associated with longer telomeres and altered expression of telomere-related genes in peripheral blood. In this study, we evaluated the asso...
Brandon L. Pierce, Jianjun Gao, Chenan Zhang, Farzana Jasmine et al.
Arsenic Exposure, Telomere Length, and Expression of Telomere-Related Genes among Bangladeshi IndividualsAbstract Number:2689 Brandon Pierce*, Jianjun Gao, Chenan Zhang, Farzana Jasmine, Shantanu Roy, Muhammad Kibriya, and Ahsan Habibul Brandon Pierce* University of Chicago, United States, E-mail Ad...
Zhen Gong, Conghui Han, Lin Hao, Jianjun Yang et al.
Abstract Objectives Superantigens have shown potent effects against bladder tumours by inducing Vβ-specific T-lymphocyte proliferation and massive cytokine release but therapeutic benefit is compromised by cytotoxicity towards non-malignant cells and hypotoxicity to major histocompability complex (M...
Gao Jianjun
Based on the equivalent model of circuit, the equations of transimpedance gain of a single-in single-out and a single-in differential-out transimpedance amplifier were first deduced. The relationship between the output impedance of a photodiode and the trans-impedance gain was analyzed, and the equa...
Xiuping Li, Jianjun Gao, Jong‐Gwan Yook, Xiaowen Xu