Jiechen Yin, Ran Liu, Zihai Jian, Dong Yang et al.
Di-(2-ethylhexyl) phthalate (DEHP) is a widely used plasticizer with a high environmental exposure level. As a persistent organic pollutant, DEHP causes reproductive and developmental toxicity in mammals. In this paper, the reproductive toxicity of DEHP was discussed using the model organism Caenorh...
Jiechen Yin, Xiang Hong, Lingyi Ma, Ran Liu et al.
The widespread use of the herbicides Atrazine (ATR) has been raised attention due to its ubiquitous occurrence in the environment. As an endocrine disruptor, ATR causes reproductive, immune, nervous system toxicity in biota. In this study, we aimed to investigate metabolic profile characteristics an...
Jia Wang, Jiechen Yin, Danhong Peng, Xiaoqian Zhang et al.
4-Nitrophenol (4-NP), as a toxic and refractory pollutant, has generated significant concern due to its adverse effects. However, the potential toxic effects and mechanism remained unclear. In this study, the reproduction, development, locomotion and reactive oxygen species (ROS) production of Caeno...
Jiechen Yin, Xiang Hong, Jia Wang, Weixi Li et al.
Atrazine (ATR), a widely used triazine herbicide, is an environmental endocrine disruptor that can cause health problems. However, whether there are multi/trans-generational reproductive impacts of ATR have not been studied. Therefore, in this study, Caenorhabditis elegans was used as a preferable m...
Weixi Li, Lingyi Ma, Yingchi Shi, Jia Wang et al.
Fenitrothion (FNT), an organophosphorus insecticide, is widely detected in the living environment. The reproductive and endocrine toxicity of FNT to biological communities has been ever reported, but potential mechanism and reproductive toxicity dose effect remain unclear. In our study, we construct...
Xiang Hong, Hanyue Zheng, Mengjie Zhao, Xiaoling Ding et al.
To explore the effects of metal exposure, vaginal microbiota, and their interactions on time to pregnancy (TTP). A total of 200 couples were recruited in Nanjing. Ultimately, 150 women from whom prepregnancy blood samples and vaginal swabs were collected by trained clinicians were included. After on...
Xiang Hong, Mengjie Zhao, Furong Tan, Hanyue Zheng et al.
To investigate the association between vaginal microbiota structure in early pregnancy and gestational diabetes mellitus (GDM) and to characterize microbial signatures for early screening for GDM. The present study was a nested case-control study recruiting pregnant women from the Nanjing Gulou Mate...
Lingling Huang, Hongqiao Li, Mengjie Zhao, Xu Wang et al.
The diet-PCOS relationship remains complex and requires further investigation. Among 1424 participants (12.3% suspected PCOS), dietary patterns were evaluated using NIH criteria via FFQ: exploratory factor analysis (EFA), EAT-Lancet dietary pattern (EAT-LDP), Mediterranean, plant-based indices. EFA ...
Li Wan, Rujing Zha, Jiecheng Ren, Ying Li et al.
ABSTRACT Impulsivity and thought suppression are two psychological traits that have great variation in healthy population. In extreme cases, both are closely related to mental illness and play an important role in behavioral addiction. We have known the role of the top-down mechanism in impulsivity ...