Jie Liu, James A Platts-Mills, Jane Juma, Furqan Kabir et al.
Background Diarrhoea is the second leading cause of mortality in children worldwide, but establishing the cause can be complicated by diverse diagnostic approaches and varying test characteristics. We used quantitative molecular diagnostic methods to reassess causes of diarrhoea in the Global Enteri...
Sofie Livio, Nancy Strockbine, Sandra Panchalingam, Sharon M. Tennant et al.
BACKGROUND: Shigella, a major diarrheal disease pathogen worldwide, is the target of vaccine development. The Global Enteric Multicenter Study (GEMS) investigated burden and etiology of moderate-to-severe diarrheal disease in children aged <60 months and matched controls without diarrhea during 3 ye...
Florian Marks, Vera von Kalckreuth, Peter Aaby, Yaw Adu‐Sarkodie et al.
BACKGROUND: Available incidence data for invasive salmonella disease in sub-Saharan Africa are scarce. Standardised, multicountry data are required to better understand the nature and burden of disease in Africa. We aimed to measure the adjusted incidence estimates of typhoid fever and invasive non-...
MalariaGEN, Ambroise D. Ahouidi, Mozam Ali, Jacob Almagro‐Garcia et al.
<ns3:p> MalariaGEN is a data-sharing network that enables groups around the world to work together on the genomic epidemiology of malaria. Here we describe a new release of curated genome variation data on 7,000 <ns3:italic>Plasmodium falciparum</ns3:italic> samples from MalariaGEN partner studies i...
Paul Farmer, Charles Patrick Almazor, Emily T. Bahnsen, Donna Barry et al.
Meeting Cholera's Challenge to Haiti and the World: A Joint Statement on Cholera Prevention and Care
Se Eun Park, Duy Pham Thanh, Christine J. Boinett, Vanessa Wong et al.
There is paucity of data regarding the geographical distribution, incidence, and phylogenetics of multi-drug resistant (MDR) Salmonella Typhi in sub-Saharan Africa. Here we present a phylogenetic reconstruction of whole genome sequenced 249 contemporaneous S. Typhi isolated between 2008-2015 in 11 s...
Brianna Lindsay, John B. Ochieng, Usman N. Ikumapayi, Aliou Touré et al.
Estimates of the prevalence of Shigella spp. are limited by the suboptimal sensitivity of current diagnostic and surveillance methods. We used a quantitative PCR (qPCR) assay to detect Shigella in the stool samples of 3,533 children aged <59 months from the Gambia, Mali, Kenya, and Bangladesh, with ...
Tracy H. Hazen, Michael S. Donnenberg, Sandra Panchalingam, Martín Antonio et al.
Enteropathogenic Escherichia coli (EPEC) are diarrhoeagenic E. coli, and are a significant cause of gastrointestinal illness among young children in developing countries. Typical EPEC are identified by the presence of the bundle-forming pilus encoded by a virulence plasmid, which has been linked to ...
Kamala Thriemer, Benedikt Ley, Albino Bobogare, Dysoley Lek et al.
The delivery of safe and effective radical cure for Plasmodium vivax is one of the greatest challenges for achieving malaria elimination from the Asia-Pacific by 2030. During the annual meeting of the Asia Pacific Malaria Elimination Network Vivax Working Group in October 2016, a round table discuss...
Robin Curry, John Barry, Andew McClenaghan
Q methodology was used to enable the identification of discourses among stakeholders to the environmental and resource dimensions of sustainability policies and to gain an understanding of the usefulness of Q methodology in informing sustainability policy development. The application of Q methodolog...
Vincenza Snow, Christel Mottur-Pilson, Ralph Gonzales
Position Papers20 March 2001Principles of Appropriate Antibiotic Use for Treatment of Nonspecific Upper Respiratory Tract Infections in AdultsVincenza Snow, MD, Christel Mottur-Pilson, PhD, and Ralph Gonzales, MD, MSPH, for the American College of Physicians–American Society of Internal Medicine*Vin...
Alan C. Swedlund, George J. Armelagos
Preface Introduction by Alan C. Swedlund and George J. Armelagos Genetic and Evolutionary Perspectives Genetics and Change by Derek F. Roberts Infectious Disease and Natural Selection in Human Populations: A Critical Reexamination by Catharina Svanborg-Eden and Bruce R. Levin The Detection of Select...
MalariaGEN, Ambroise D. Ahouidi, Mozam Ali, Jacob Almagro‐Garcia et al.
<ns3:p>MalariaGEN is a data-sharing network that enables groups around the world to work together on the genomic epidemiology of malaria. Here we describe a new release of curated genome variation data on 7,000 <ns3:italic>Plasmodium falciparum</ns3:italic> samples from MalariaGEN partner studies in...
MalariaGEN, Ishag Adam, Mohammad Shafiul Alam, Sisay Getachew Alemu et al.
<ns3:p> This report describes the MalariaGEN Pv4 dataset, a new release of curated genome variation data on 1,895 samples of <ns3:italic>Plasmodium vivax</ns3:italic> collected at 88 worldwide locations between 2001 and 2017. It includes 1,370 new samples contributed by MalariaGEN and VivaxGEN partn...
Se Eun Park, Duy Pham Thanh, Gi Deok Pak, Ursula Panzner et al.
Background Invasive non-typhoidal Salmonella (iNTS) is one of the leading causes of bacteraemia in sub-Saharan Africa. We aimed to provide a better understanding of the genetic characteristics and transmission patterns associated with multi-drug resistant (MDR) iNTS serovars across the continent. Me...