Gwen Tindula, Sudipta Kumer Mukherjee, Sheikh Muhammad Ekramullah, DM Arman et al.
BACKGROUND: Neural tube defects are a pressing public health concern despite advances in prevention from folic acid-based strategies. Numerous chemicals, in particular arsenic, have been associated with neural tube defects in animal models and could influence risk in humans. OBJECTIVES: We investiga...
Kelsey Gleason, Linda Valeri, Anuraj H. Shankar, John F. Obrycki et al.
BACKGROUND: Many children in Bangladesh experience poor nutritional status and environmental lead exposure, both of which are associated with lower scores on neurodevelopmental assessments. Recent studies have suggested that part of lead's adverse effects on neurodevelopment are caused in part by le...
John F. Obrycki, Jane J. Lee, Kush Kapur, Ligi Paul et al.
OBJECTIVES: Mothers need a nutrient-rich diet for healthy neural tube development. Neural tube defect risk can be reduced through fortifying grain products with folic acid and taking folic acid supplements. Fortification is not required in Bangladesh. Maternal supplement use rates are low, similar t...
Abby F. Fleisch, Sudipta Kumer Mukherjee, Subrata Kumar Biswas, John F. Obrycki et al.
BACKGROUND: Arsenic exposure has been associated with gestational diabetes mellitus. However, the extent to which arsenic exposure during pregnancy is associated with postpartum glucose intolerance is unknown. METHODS: We studied 323 women in Bangladesh. We assessed arsenic exposure in early pregnan...
Chih‐Fu Wei, John F. Obrycki, Gwen Tindula, Sudipta Kumer Mukherjee et al.
BACKGROUND AND AIM: Arsenic is associated with multiple adverse reproductive outcomes, and previous studies suggested higher risk of neural tube defects among mothers exposed to higher concentration of well water arsenic in Bangladesh. We further examine the association using water arsenic as proxy ...
Gwen Tindula, Sudipta Kumer Mukherjee, Sheikh Muhammad Ekramullah, DM Arman et al.
Background: Neural tube defects, severe birth defects that occur when the neural plate fails to close in early gestation, continue to be a pressing public health concern, despite advances in prevention from folic acid-based strategies. Arsenic, a chemical naturally occurring in soils and drinking wa...