Heather Lowers, George N. Breit, Andrea L. Foster, John W. Whitney et al.
Kenneth G. Stollenwerk, George N. Breit, Alan H. Welch, James C. Yount et al.
Recognition of arsenic (As) contamination of shallow fluvio-deltaic aquifers in the Bengal Basin has resulted in increasing exploitation of groundwater from deeper aquifers that generally contain low concentrations of dissolved As. Pumping-induced infiltration of high-As groundwater could eventually...
R. T. Cunningham, Ian Young, John Winder, Marina O’Kane et al.
A radioimmunoassay has been developed and used to measure serum neurone specific enolase (NSE) concentrations in 24 patients, following cerebral infarction. A significant correlation between cerebral infarct volume and maximum serum NSE concentration was observed (P = 0.047). Serum NSE was also assa...
Zachary J. Madewell, Cynthia G. Whitney, Sithembiso Velaphi, Portia Mutevedzi et al.
Importance: Although child mortality trends have decreased worldwide, deaths among children younger than 5 years of age remain high and disproportionately circumscribed to sub-Saharan Africa and Southern Asia. Tailored and innovative approaches are needed to increase access, coverage, and quality of...
Dianna M. Blau, Vicky L. Baillie, Toyah Els, Sana Mahtab et al.
BACKGROUND: Lower respiratory tract infections are a leading cause of death in young children, but few studies have collected the specimens needed to define the role of specific causes. The Child Health and Mortality Prevention Surveillance (CHAMPS) platform aims to investigate causes of death in ch...
Sana Mahtab, Dianna M. Blau, Zachary J. Madewell, Ikechukwu U. Ogbuanu et al.
BACKGROUND: The Child Health and Mortality Prevention Surveillance (CHAMPS) Network programme undertakes post-mortem minimally invasive tissue sampling (MITS), together with collection of ante-mortem clinical information, to investigate causes of childhood deaths across multiple countries. We aimed ...
Lola Madrid, Kartavya J. Vyas, Vijaya Kancherla, Haleluya Leulseged et al.
BACKGROUND: Neural tube defects are common birth defects resulting in severe morbidity and mortality; they can largely be prevented with periconceptional maternal intake of folic acid. Understanding the occurrence of neural tube defects and their contribution to mortality in settings where their bur...
Kenneth G. Stollenwerk, George N. Breit, Alan H. Welch, James C. Yount et al.
Sana Mahtab, Zachary J. Madewell, Shabir A. Madhi, Amy Wise et al.
Abstract Background Invasive Group B Streptococcus (GBS) is a common cause of early-onset neonatal sepsis and is also associated with stillbirth. This study aimed to determine the proportion of stillborn infants and infants who died between 0 and 90 days attributable to GBS using postmortem minimall...
Chris A. Rees, Kitiezo Aggrey Igunza, Zachary J. Madewell, Victor Akelo et al.
Background: Most childhood deaths globally are considered preventable through high-quality clinical care, which includes adherence to clinical care recommendations. Our objective was to describe adherence to World Health Organization recommendations for the management of leading causes of death amon...
George N. Breit, James C. Yount, Md. Nehal Uddin, Ad. Atual Muneem et al.
Processes active within sediment of the Bengal basin have attracted world concern because of the locally high content of arsenic dissolved in ground water drawn from that sediment. Sediment samples were collected from a borehole in the town of Rajoir, Rajoir upazila, Madaripur district, Bangladesh, ...
George N. Breit, James C. Yount, Md. Nehal Uddin, Ad. Atual Muneem et al.
Processes active within sediment of the Bengal delta have attracted world concern because of the locally high content of arsenic dissolved in ground water drawn from that sediment. Sediment samples were collected from two boreholes in Srirampur village, Kachua upazila, Chandphur district, Bangladesh...
Sara Ajanovic, Zachary J. Madewell, Shams El Arifeen, Emily S. Gurley et al.
Importance: The emergence of acute neurological symptoms in children necessitates immediate intervention. Although low- and middle-income countries (LMICs) bear the highest burden of neurological diseases, there is a scarcity of diagnostic and therapeutic resources. Therefore, current understanding ...
Afruna Rahman, Meghna Ray, Zachary J. Madewell, Kitiezo Aggrey Igunza et al.
Importance: Most of the 2.3 million annual neonatal deaths occur in sub-Saharan Africa and South Asia, with perinatal asphyxia and neonatal sepsis being the leading causes of neonatal mortality. Most neonatal deaths are considered preventable through high-quality clinical care, which includes adhere...
Laiz Laura de Godoy, Kheng Choon Lim, Archith Rajan, Gaurav Verma et al.
Purpose Isocitrate dehydrogenase (IDH) mutation has become one of the most important prognostic biomarkers in glioma management, indicating better treatment response and prognosis. IDH mutations confer neomorphic activity leading to the conversion of alpha-ketoglutarate (α-KG) to 2-hydroxyglutarate ...