Luregn J. Schlapbach, R. Scott Watson, Lauren R. Sorce, Andrew C. Argent et al.
Importance: Sepsis is a leading cause of death among children worldwide. Current pediatric-specific criteria for sepsis were published in 2005 based on expert opinion. In 2016, the Third International Consensus Definitions for Sepsis and Septic Shock (Sepsis-3) defined sepsis as life-threatening org...
Meagan Harper, Hebah Mejbel, Dylan Longert, Robin Abell et al.
Abstract Freshwater biodiversity is declining at an unprecedented rate. Freshwater conservationists and environmental managers have enough evidence to demonstrate that action must not be delayed but have insufficient evidence to identify those actions that will be most effective in reversing the cur...
Maria Deloria Knoll, Julia C. Bennett, Maria Garcia Quesada, E. Wangeci Kagucia et al.
Serotype-specific surveillance for invasive pneumococcal disease (IPD) is essential for assessing the impact of 10- and 13-valent pneumococcal conjugate vaccines (PCV10/13). The Pneumococcal Serotype Replacement and Distribution Estimation (PSERENADE) project aimed to evaluate the global evidence to...
Julia C. Bennett, Maria Deloria Knoll, E. Wangeci Kagucia, Maria Garcia Quesada et al.
BACKGROUND: Pneumococcal conjugate vaccines (PCVs) that are ten-valent (PCV10) and 13-valent (PCV13) became available in 2010. We evaluated their global impact on invasive pneumococcal disease (IPD) incidence in all ages. METHODS: Serotype-specific IPD cases and population denominators were obtained...
R. Abbasi, M. Ackermann, J. Adams, Sanjib Kumar Agarwalla et al.
A measurement of the diffuse astrophysical neutrino spectrum is presented using IceCube data collected from 2011--2022 (10.3 years). We developed novel detection techniques to search for events with a contained vertex and exiting track induced by muon neutrinos undergoing a charged-current interacti...
R. Abbasi, M. Ackermann, J. Adams, N. Aggarwal et al.
Abstract IceCube, a cubic-kilometer array of optical sensors built to detect atmospheric and astrophysical neutrinos between 1 GeV and 1 PeV, is deployed 1.45 km to 2.45 km below the surface of the ice sheet at the South Pole. The classification and reconstruction of events from the in-ice detectors...
Rasha Abbasi, M. Ackermann, J. Adams, Sanjib Kumar Agarwalla et al.
We present a search for the diffuse extremely-high-energy neutrino flux using 12.6 years of IceCube data. The nonobservation of neutrinos with energies well above 10 PeV constrains the all-flavor neutrino flux at 10^{18} eV to a level of E^{2}Φ_{ν_{e}+ν_{μ}+ν_{τ}}≃10^{-8} GeV cm^{-2} s^{-1} sr^{-1},...
Julia C. Bennett, Marissa K. Hetrich, Maria Garcia Quesada, Jenna N. Sinkevitch et al.
serotype 1 (ST1) was an important cause of invasive pneumococcal disease (IPD) globally before the introduction of pneumococcal conjugate vaccines (PCVs) containing ST1 antigen. The Pneumococcal Serotype Replacement and Distribution Estimation (PSERENADE) project gathered ST1 IPD surveillance data f...
Alex Shaw, Catherine Troman, Joyce Akello, Kathleen O’Reilly et al.
Alpaslan Özerdem, Rebecca Roberts
Contents: Introduction Part I Concepts, Issues and Challenges: Global agriculture and the challenge of sustainability, Moya Kneafsey The impact of conflict on agriculture and post-conflict reconstruction challenges, Alpaslan A-zerdem and Rebecca Roberts Projections on future challenges: climate chan...
R. Abbasi, M. Ackermann, J. Adams, N. Aggarwal et al.
Abstract The D-Egg, an acronym for “Dual optical sensors in an Ellipsoid Glass for Gen2,” is one of the optical modules designed for future extensions of the IceCube experiment at the South Pole. The D-Egg has an elongated-sphere shape to maximize the photon-sensitive effective area while maintainin...
R. Abbasi, M. Ackermann, J. Adams, Sanjib Kumar Agarwalla et al.
This Letter presents the result of a 3+1 sterile neutrino search using 10.7 yr of IceCube data. We analyze atmospheric muon neutrinos that traverse the Earth with energies ranging from 0.5 to 100 TeV, incorporating significant improvements in modeling neutrino flux and detector response compared to ...
Simon N. Stuart, Shaikha Al Dhaheri, Elizabeth L. Bennett, Duan Biggs et al.
Abstract A controversy at the 2016 IUCN World Conservation Congress on the topic of closing domestic ivory markets (the 007, or so-called James Bond, motion) has given rise to a debate on IUCN's value proposition. A cross-section of authors who are engaged in IUCN but not employed by the organizatio...
R. Abbasi, M. Ackermann, J. Adams, J. A. Aguilar et al.
Abstract The Surface Enhancement of the IceTop air-shower array will include the addition of radio antennas and scintillator panels, co-located with the existing ice-Cherenkov tanks and covering an area of about 1 km 2 . Together, these will increase the sensitivity of the IceCube Neutrino Observato...
Samuel Alldritt, J.S.B. Ramirez, Reinder Vos de Wael, Richard A. I. Bethlehem et al.
Recent efforts to chart human brain growth across the lifespan using large-scale MRI data have provided reference standards for human brain development. However, similar models for nonhuman primate (NHP) growth are lacking. The rhesus macaque, a widely used NHP in translational neuroscience due to i...