Andreas D. Haas, Karl‐Günter Technau, Shenaaz Pahad, Kate Braithwaite et al.
INTRODUCTION: Mental health problems are prevalent in adolescents living with HIV (ALHIV), often remain untreated, and may negatively affect antiretroviral therapy (ART) adherence and viral suppression. We implemented routine mental health screening at a paediatric ART clinic to improve the identifi...
Karl‐Günter Technau, Erica Lazarus, Louise Kuhn, Elaine J. Abrams et al.
BACKGROUND: Concerns about stavudine (d4T) toxicity have led to increased use of abacavir (ABC) in first-line pediatric antiretroviral treatment (ART) regimens. Field experience with ABC in ART-naïve children is limited. METHODS: Deidentified demographic, clinical and laboratory data on HIV-infected...
Priscilla Ruvimbo Tsondai, Annette H. Sohn, Sam Phiri, Kombatende Sikombe et al.
INTRODUCTION: As adolescents and young people living with HIV (AYLH) age, they face a "transition cascade," a series of steps associated with transitions in their care as they become responsible for their own healthcare. In high-income countries, this usually includes transfer from predominantly pae...
Laura Rossouw, Nkosinathi Ngcobo, Kate Clouse, Cornelius Nattey et al.
Background: The use of big data and large language models in healthcare can play a key role in improving patient treatment and healthcare management, especially when applied to large-scale administrative data. A major challenge to achieving this is ensuring that patient confidentiality and personal ...
Katherine M. Laycock, Karl‐Günter Technau, Patricia Lelo, Watsamon Jantarabenjakul et al.
BACKGROUND: Tuberculosis (TB) remains a leading cause of morbidity and mortality for children living with HIV (CLHIV), with gaps in TB screening, diagnostics, management, and TB preventive therapy (TPT). We investigated reported practices in these domains at sites caring for CLHIV in low- and middle...
James G. Carlucci, Thomas Huntington, Karl‐Günter Technau, Marcel Yotebieng et al.
In a large, multiregional cohort of African infants with human immunodeficiency virus (HIV) exposure, 44% of those with a positive HIV polymerase chain reaction test lacked a confirmatory positive test. Efforts are needed to ensure high-fidelity implementation of HIV testing algorithms so that all p...