Dovini Jayasinghe, Md. Moksedul Momin, Kerri Beckmann, Elina Hyppönen et al.
The use of polygenic risk score (PRS) models has transformed the field of genetics by enabling the prediction of complex traits and diseases based on an individual's genetic profile. However, the impact of genotype-environment interaction (GxE) on the performance and applicability of PRS models rema...
Dovini Jayasinghe, Md. Moksedul Momin, Kerri Beckmann, Elina Hyppönen et al.
Abstract The use of polygenic risk score (PRS) models has transformed the field of genetics by enabling the prediction of complex traits and diseases based on an individual’s genetic profile. However, the impact of genotype-environment interaction (GxE) on the performance and applicability of PRS mo...