Khalequz Zaman, Eliza Roy, Shams El Arifeen, Mahbubur Rahman et al.
BACKGROUND: Young infants and pregnant women are at increased risk for serious consequences of influenza infection. Inactivated influenza vaccine is recommended for pregnant women but is not licensed for infants younger than 6 months of age. We assessed the clinical effectiveness of inactivated infl...
Md Mizanur Rahman, Marie Vahter, Mohammad Abdul Wahed, Nazmul Sohel et al.
STUDY OBJECTIVE: To assess prevalence of arsenic exposure through drinking water and skin lesions, and their variation by geographical area, age, sex, and socioeconomic conditions. DESIGN, SETTING, AND PARTICIPANTS: Skin lesion cases were identified by screening the entire population above 4 years o...
Khalequz Zaman
A community-based logitudinal study conducted in Matlab, a rural area in Bangladesh, investigated acute respiratory infections (ARI) among children. A cohort of 696 children under 5 years of age was followed for 1 year yielding 183,865 child-days of observation. Trained field workers visited the stu...
Robert F. Breiman, Khalequz Zaman, George Armah, Samba O. Sow et al.
Background Efficacy of the pentavalent rotavirus vaccine (PRV), RotaTeq(®), against severe rotavirus gastroenteritis (RVGE) was evaluated in two double-blind, placebo-controlled, multicenter Phase III clinical trials conducted in GAVI-eligible countries in Africa (Ghana, Kenya, and Mali) and in Asia...
Kazi Mizanur Rahman, Shams El Arifeen, Khalequz Zaman, Mahbubur Rahman et al.
In double-blind trials in Bangladesh, 88 adults, and 79 children (8-10 years) were randomized to receive either a single oral dose of 1 × 10(4), 1 × 10(5) or 1 × 10(6)CFU of SC602 (a live, attenuated Shigella flexneri 2a strain vaccine) or placebo. In the adult outpatient 1 × 10(6) CFU group, severe...
Jane Gidudu, David A. Sack, Mónica Pina, Michael J. Hudson et al.
. Gidudua,∗, D.A. Sackb, M. Pinac, M.J. Hudsond, K.S. Kohla, P. Bishope, A. Chatterjee f, E. Chiappinig, . Compingbutraa, C. da Costah, R. Fernandopulle i, T.K. Fischer j, P. Habera, W. Masanak, artins R. de Menezes l, G. Kangm, N. Khuri-Bulosn, L.A. Killiono, C. Nairp, G. Poerschkeq, B. Rathr, . Sa...
Tracey Pérez Koehlmoos, Rukhsana Gazi, Shahed Hossain, Khalequz Zaman
BACKGROUND: Social franchising has developed as a possible means of improving provision of health services through engaging the non-state sector in low- and middle-income countries. OBJECTIVES: To examine the evidence that social franchising has on access to and quality of health services in low- an...
Christine Marie George, W. Abdullah Brooks, Joseph H. Graziano, Bareng A. S. Nonyane et al.
BACKGROUND: Pneumonia is the leading cause of death for children under 5 years of age globally, making research on modifiable risk factors for childhood pneumonia important for reducing this disease burden. Millions of children globally are exposed to elevated levels of arsenic in drinking water. Ho...
Haruko Takeuchi, Khalequz Zaman, Juri Takahashi, Mohammad Yunus et al.
BACKGROUND: Increasing interest has arisen whether helminthic infections protect against asthma and allergy. The prevalence of wheezing among Bangladeshi children is higher in rural areas where helminthic infectious burden is greater, which is contrary to the general assumption. OBJECTIVE: We theref...
Elizabeth T. Rogawski McQuade, James A Platts-Mills, E. Ross Colgate, Rashidul Haque et al.
Background: The low efficacy of rotavirus vaccines in clinical trials performed in low-resource settings may be partially explained by acquired immunity from natural exposure, especially in settings with high disease incidence. Methods: In a clinical trial of monovalent rotavirus vaccine in Banglade...
Khalequz Zaman, Mohammad Yunus, Shams El Arifeen, Abdullah H Baqui et al.
The objective of the study was to determine the prevalence of smear-positive tuberculosis (TB) in a rural area in Bangladesh at Matlab. A TB surveillance system was established among 106,000 people in rural Bangladesh at Matlab. Trained field workers interviewed all persons aged > or = 15 years to d...
Mustafizur Rahman, Rasheda Sultana, Goutam Podder, Abu SG Faruque et al.
BACKGROUND: Rotavirus genotyping is performed by using reverse transcription PCR with type-specific-primers. Because the high rotavirus mutation rate generates an extensive genomic variation, different G-type-specific primer sets are applied in different geographical locations. In Bangladesh, a sign...
Khalequz Zaman, Haruko Takeuchi, Mohammad Yunus, Shams El Arifeen et al.
Objective Although bronchial asthma causes a great deal of morbidity among children in Bangladesh, few epidemiological studies addressed this problem. The study aims to determine the prevalence of wheezing and its association with environmental and host factors. Methods A total of 1587 children aged...
Abdullah H Baqui, Robert E. Black, Christa L. Fischer Walker, Shams El Arifeen et al.
Objective Zinc deficiency is very common in developing countries and is more pronounced during an episode of diarrhea. Supplementation with zinc improves diarrhea and might correct zinc deficiency in both the short and longer term. Method We conducted a nested study within a cluster randomized treat...
Kristen Lewis, Michael J. Dallas, John C. Victor, Max Ciarlet et al.
Background Clinical severity scoring systems are used in rotavirus vaccine efficacy and effectiveness studies to define the primary endpoint, severe rotavirus gastroenteritis (RVGE). Understanding how scoring systems perform in diverse settings is critical for proper design and interpretation. This ...