Shannon M. Smith, Robert H. Dworkin, Dennis C. Turk, Ralf Baron et al.
Valid and reliable biomarkers can play an important role in clinical trials as indicators of biological or pathogenic processes or as a signal of treatment response. Currently, there are no biomarkers for pain qualified by the US Food and Drug Administration or the European Medicines Agency for use ...
Rex Park, Anthony M.‐H. Ho, Gisèle Pickering, Lars Arendt‐Nielsen et al.
BACKGROUND: Chronic pain is a highly prevalent and complex health problem that is associated with a severe symptom burden, as well as substantial economic and social impact. Many patients with chronic pain still suffer from unrelieved or undertreated pain due to the incomplete efficacy and dose-limi...
Lars Arendt‐Nielsen
“Pain medicine” is a discipline within the field of medicine that is concerned with the prevention of pain and the evaluation, treatment, and rehabilitation of persons in pain. Suboptimal management of pain is still an overgrown concern worldwide. Chronic pain is widespread in society, and 13.5 to 4...