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Results for “"Laurie E. Comstock"”

2 results

Initial Clinical Studies of CVD 112 Vibrio cholerae O139 Live Oral Vaccine: Safety and Efficacy against Experimental Challenge

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C. O. Tacket, G Losonsky, James P. Nataro, Laurie E. Comstock et al.

Journal: The Journal of Infectious DiseasesYear: 1995Citations: 103

Since October 1992, epidemics of cholera associated with Vibrio cholerae O group 139 have occurred in India, Bangladesh, and much of the rest of Asia. A volunteer model was used to determine the safety, immunogenicity, and efficacy of an attenuated delta ctxA delta zot delta ace delta cep V. cholera...

Life SciencesBiochemistry, Genetics and Molecular BiologyEndocrinology
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Distribution of Zonula occludens toxin (zot) gene among clinical isolates of Vibrio cholerae O1 from Bangladesh and Africa.

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Shah M. Faruque, Laurie E. Comstock, James B. Kaper, Albert Mj

Journal: PubMedYear: 1994Citations: 17

Seventy-two clinical isolates of Vibrio cholerae O1 from Bangladesh, and 12 and 9 isolates respectively from Tanzania and Nigeria were screened for sequences homologous to zonula occludens toxin (zot) and cholera toxin (ctx) genes. As observed previously, all isolates in the present study also posse...

Life SciencesBiochemistry, Genetics and Molecular BiologyEndocrinology
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