Stephen P. Luby, Mahbubur Rahman, Benjamin F. Arnold, Leanne Unicomb et al.
BACKGROUND: Diarrhoea and growth faltering in early childhood are associated with subsequent adverse outcomes. We aimed to assess whether water quality, sanitation, and handwashing interventions alone or combined with nutrition interventions reduced diarrhoea or growth faltering. METHODS: The WASH B...
Robert Dreibelbis, Peter J. Winch, Elli Leontsini, Kristyna R. S. Hulland et al.
BACKGROUND: Promotion and provision of low-cost technologies that enable improved water, sanitation, and hygiene (WASH) practices are seen as viable solutions for reducing high rates of morbidity and mortality due to enteric illnesses in low-income countries. A number of theoretical models, explanat...
Audrie Lin, Benjamin F. Arnold, Sadia Afreen, Rie Goto et al.
We assessed the relationship of fecal environmental contamination and environmental enteropathy. We compared markers of environmental enteropathy, parasite burden, and growth in 119 Bangladeshi children (≤ 48 months of age) across rural Bangladesh living in different levels of household environmenta...
Mahbub‐Ul Alam, Stephen P. Luby, Amal Halder, Khairul Islam et al.
BACKGROUND: Many adolescent girls in low-income and middle-income countries lack appropriate facilities and support in school to manage menstruation. Little research has been conducted on how menstruation affects school absence. This study examines the association of menstrual hygiene management kno...
Emily K. Rousham, Leanne Unicomb, Mohammad Aminul Islam
Antibiotic resistance (ABR) is recognized as a One Health challenge because of the rapid emergence and dissemination of resistant bacteria and genes among humans, animals and the environment on a global scale. However, there is a paucity of research assessing ABR contemporaneously in humans, animals...
Benjamin F. Arnold, Clair Null, Stephen P. Luby, Leanne Unicomb et al.
INTRODUCTION: Enteric infections are common during the first years of life in low-income countries and contribute to growth faltering with long-term impairment of health and development. Water quality, sanitation, handwashing and nutritional interventions can independently reduce enteric infections ...
Ayşe Ercümen, Amy J. Pickering, Laura H. Kwong, Benjamin F. Arnold et al.
in food (p < 0.05). E. coli in stored water and food increased with increasing E. coli in soil, ponds, source water and hands. We provide empirical evidence of fecal transmission in the domestic environment despite on-site sanitation. Animal feces contribute to fecal contamination, and fecal indicat...
Stephen P. Luby, Amal Halder, Tarique Md. Nurul Huda, Leanne Unicomb et al.
BACKGROUND: Standard public health interventions to improve hand hygiene in communities with high levels of child mortality encourage community residents to wash their hands with soap at five separate key times, a recommendation that would require mothers living in impoverished households to typical...
Leanne Unicomb, Goutam Podder, Jon R. Gentsch, Patricia Woods et al.
We characterized 1,534 rotavirus (RV) strains collected in Bangladesh from 1992 to 1997 to assess temporal changes in G type and to study the most common G and P types using reverse transcription-PCR, oligonucleotide probe hybridization, and monoclonal antibody-based enzyme immunoassay. Results from...
Tarique Md. Nurul Huda, Leanne Unicomb, Richard B. Johnston, Amal Halder et al.
Started in 2007, the Sanitation Hygiene Education and Water Supply in Bangladesh (SHEWA-B) project aims to improve the hygiene, sanitation and water supply for 20 million people in Bangladesh, and thus reduce disease among this population. This paper assesses the effectiveness of SHEWA-B on changing...
Abdullah Al Masud, Emily K. Rousham, Mohammad Aminul Islam, Mahbub‐Ul Alam et al.
Background: There is increasing concern around the use of antibiotics in animal food production and the risk of transmission of antimicrobial resistance within the food chain. In many low and middle-income countries, including Bangladesh, the commercial poultry sector comprises small-scale producers...
Firdausi Qadri, Mohammad Ali, Fahima Chowdhury, Ashraful Islam Khan et al.
Background Cholera is endemic in Bangladesh with epidemics occurring each year. The decision to use a cheap oral killed whole-cell cholera vaccine to control the disease depends on the feasibility and effectiveness of vaccination when delivered in a public health setting. We therefore assessed the f...
Kristyna R. S. Hulland, Elli Leontsini, Robert Dreibelbis, Leanne Unicomb et al.
BACKGROUND: In Bangladesh diarrhoeal disease and respiratory infections contribute significantly to morbidity and mortality. Handwashing with soap reduces the risk of infection; however, handwashing rates in infrastructure-restricted settings remain low. Handwashing stations--a dedicated, convenient...
AK Mitra, Dilip Mahalanabis, Hasan Ashraf, Leanne Unicomb et al.
The therapeutic efficacy of hyperimmune bovine colostrum (HBC) from cows immunized with four serotypes of human rotavirus was evaluated in a double-blind, randomized trial in 75 boys, aged 6-24 months, infected with rotavirus diarrhoea. The treatment group received 100 ml of HBC three times a day fo...
Mohanraj Ramachandran, Carl D. Kirkwood, Leanne Unicomb, Nigel A. Cunliffe et al.
Between 1992 and 1998, serotype G9 human rotavirus (RV) strains have been detected in 10 countries, including Thailand, India, Brazil, Bangladesh, Malawi, Italy, France, the United States, the United Kingdom, and Australia, suggesting the possible emergence of the fifth common serotype worldwide. Un...