David F. Choy, Kevin M. Hart, Lee A. Borthwick, Aarti Shikotra et al.
Increasing evidence suggests that asthma is a heterogeneous disorder regulated by distinct molecular mechanisms. In a cross-sectional study of asthmatics of varying severity (n = 51), endobronchial tissue gene expression analysis revealed three major patient clusters: TH2-high, TH17-high, and TH2/17...
Emily R. Smith, Anuraj H. Shankar, Lee Wu, Said Aboud et al.
BACKGROUND: Micronutrient deficiencies are common among women in low-income and middle-income countries. Data from randomised trials suggest that maternal multiple micronutrient supplementation decreases the risk of low birthweight and potentially improves other infant health outcomes. However, hete...
Keith P. West, Abu Ahmed Shamim, Sucheta Mehra, Alain Labrique et al.
<h3>Importance</h3> Maternal micronutrient deficiencies may adversely affect fetal and infant health, yet there is insufficient evidence of effects on these outcomes to guide antenatal micronutrient supplementation in South Asia. <h3>Objective</h3> To assess effects of antenatal multiple micronutrie...
Keith P. West, Parul Christian, Alain Labrique, Mahbubur Rashid et al.
CONTEXT: Maternal vitamin A deficiency is a public health concern in the developing world. Its prevention may improve maternal and infant survival. OBJECTIVE: To assess efficacy of maternal vitamin A or beta carotene supplementation in reducing pregnancy-related and infant mortality. DESIGN, SETTING...
Gerold Rahmann, Mohammad Reza Ardakani, Paolo Bàrberi, Herwart Boehm et al.
Yuan-Li Tsai, Dat P. Ha, He Zhao, Anthony J. Carlos et al.
The discovery that endoplasmic reticulum (ER) luminal chaperones such as GRP78/BiP can escape to the cell surface upon ER stress where they regulate cell signaling, proliferation, apoptosis, and immunity represents a paradigm shift. Toward deciphering the mechanisms, we report here that, upon ER str...
Kerry Schulze, Sucheta Mehra, Saijuddin Shaikh, Hasmot Ali et al.
BACKGROUND: Antenatal multiple micronutrient (MM) supplementation improves birth outcomes relative to iron-folic acid (IFA) in developing countries, but limited data exist on its impact on pregnancy micronutrient status. OBJECTIVE: We assessed the efficacy of a daily MM (15 nutrients) compared with ...
Muzi Na, Sucheta Mehra, Parul Christian, Hasmot Ali et al.
Background Household food insecurity (HFI) can lead to a poor diet and malnutrition. Yet, little is known about the extent to which maternal diet covaries with food insecurity during pregnancy and lactation. Objective Longitudinal associations between HFI and maternal dietary diversity from early pr...
Kamala Thriemer, Albino Bobogare, Benedikt Ley, Clarice Samo Gudo et al.
The goal to eliminate malaria from the Asia-Pacific by 2030 will require the safe and widespread delivery of effective radical cure of malaria. In October 2017, the Asia Pacific Malaria Elimination Network Vivax Working Group met to discuss the impediments to primaquine (PQ) radical cure, how these ...
Sarah M. Durant, Matthew S. Becker, Scott Creel, Sultana Bashir et al.
Summary In dryland ecosystems, mobility is essential for both wildlife and people to access unpredictable and spatially heterogeneous resources, particularly in the face of climate change. Fences can prevent connectivity vital for this mobility. There are recent calls for large‐scale barrier fencing...
Minsheng You, Fushi Ke, Shijun You, Zhangyan Wu et al.
The diamondback moth, Plutella xylostella is a cosmopolitan pest that has evolved resistance to all classes of insecticide, and costs the world economy an estimated US $4-5 billion annually. We analyse patterns of variation among 532 P. xylostella genomes, representing a worldwide sample of 114 popu...
Huaping Wang, Jianmin Ma, Jun Zhang, Yuezhan Feng et al.
Gas sensor technology is widely utilized in various areas ranging from home security, environment and air pollution, to industrial production. It also hold great promise in non-invasive exhaled breath detection and an essential device in future internet of things. The past decade has witnessed giant...
Md. Abu Hanif, Insup Lee, Jeasmin Akter, Md. Islam et al.
ZnO nanoparticles (ZnO-NPs) were synthesized by a straightforward modified thermal method using only one chemical: zinc acetate dihydrate. The process is environmentally safer than other methods because it does not involve other chemicals or a catalyst, acid, or base source. X-ray diffraction analys...
Shegufta Shefa Sikder, Alain Labrique, Abu Ahmed Shamim, Hasmot Ali et al.
BACKGROUND: In rural Bangladesh, more than 75% of all births occur at home in the absence of skilled birth attendants. Population-based data are lacking on the burden and risk factors for obstetric complications in settings with low rates of institutional delivery. We sought to describe the prevalen...
Abu Ahmed Shamim, Kerry Schulze, Rebecca D. Merrill, Alamgir Kabir et al.
Background Tocopherols were discovered for their role in animal reproduction, but little is known about the contribution of deficiencies of vitamin E to human pregnancy loss. Objective We sought to determine whether higher first-trimester concentrations of α-tocopherol and γ-tocopherol were associat...