Sweta Patel, Mohammad Arif Rahman, M. Mohasin, M. Asrafuzzaman Riyadh et al.
Vibrio cholerae O1 causes cholera, a dehydrating diarrheal disease. We have previously shown that V. cholerae-specific memory B cell responses develop after cholera infection, and we hypothesize that these mediate long-term protective immunity against cholera. We prospectively followed household con...
Mohammad Murshid Alam, M. Asrafuzzaman Riyadh, Kaniz Fatema, Mohammad Arif Rahman et al.
The mediators of protective immunity against cholera are currently unknown, but memory B-cell responses may play a central role in facilitating long-term and anamnestic responses against Vibrio cholerae, the cause of cholera. We compared memory B-cell responses in adults with natural cholera in Bang...
Daniel T. Leung, Mohammad Arif Rahman, M. Mohasin, Sweta Patel et al.
Current oral cholera vaccines induce lower protective efficacy and shorter duration of protection against cholera than wild-type infection provides, and this difference is most pronounced in young children. Despite this, there are limited data comparing immune responses in children following wild-ty...
Daniel T. Leung, Mohammad Arif Rahman, M. Mohasin, M. Asrafuzzaman Riyadh et al.
Children bear a large component of the global burden of cholera. Despite this, little is known about immune responses to cholera in children, especially those under 5 years of age. Cholera vaccine studies have demonstrated lower long-term protective efficacy in young children than in older children ...
Naofumi Ito, M. Asrafuzzaman Riyadh, Shah Adil Ishtiyaq Ahmad, Satoko Hattori et al.
The lateral ventricle (LV) is flanked by the subventricular zone (SVZ), a neural stem cell (NSC) niche rich in extrinsic growth factors regulating NSC maintenance, proliferation, and neuronal differentiation. Dysregulation of the SVZ niche causes LV expansion, a condition known as hydrocephalus; how...
Daniel T. Leung, Mohammad Arif Rahman, M. Mohasin, Sweta Patel et al.
Current oral cholera vaccines induce lower protective efficacy and shorter duration of protection against cholera than wild-type infection provides, and this difference is most pronounced in young children. Despite this, there are limited data comparing immune responses in children following wild-ty...