Christine Marie George, Shirajum Monira, David A. Sack, Mahamud‐ur Rashid et al.
The risk for cholera infection is >100 times higher for household contacts of cholera patients during the week after the index patient seeks hospital care than it is for the general population. To initiate a standard of care for this high-risk population, we developed Cholera-Hospital-Based-Interven...
Christine Marie George, Shwapon Biswas, Danielle Jung, Jamie Perin et al.
Inadequate hand hygiene is estimated to result in nearly 300,000 deaths annually, with the majority of deaths being among children younger than 5 years. In an effort to promote handwashing with soap and water treatment behaviors among highly susceptible household members of cholera patients, we rece...
Mahamud‐ur Rashid, Mathieu Almeida, Andrew S. Azman, Brianna Lindsay et al.
Vibrio cholerae causes cholera, a severe diarrheal disease. Understanding the local genetic diversity and transmission of V. cholerae will improve our ability to control cholera. Vibrio cholerae isolates clustered in genetically related groups (clonal complexes, CC) by multilocus variable tandem-rep...
Sameer Dixit, Fatema‐Tuz Johura, Sulochana Manandhar, Abdus Sadique et al.
BACKGROUND: Although endemic cholera causes significant morbidity and mortality each year in Nepal, lack of information about the causal bacterium often hinders cholera intervention and prevention. In 2012, diarrheal outbreaks affected three districts of Nepal with confirmed cases of mortality. This...
Christine Marie George, Mahamud‐ur Rashid, David A. Sack, R. Bradley Sack et al.
BACKGROUND: To evaluate the specificity of the Crystal VC dipstick test for detecting cholera. METHODS: We compared direct testing using the Crystal VC dipstick test and testing after enrichment for 6 h in alkaline peptone water (APW) to bacterial culture as the gold standard. Samples positive by di...
Raisa Rafique, Mahamud‐ur Rashid, Shirajum Monira, Zillur Rahman et al.
Recurrent cholera causes significant morbidity and mortality among the growing population of Dhaka, the capital city of Bangladesh. Previous studies have demonstrated that household contacts of cholera patients are at >100 times higher risk of cholera during the week after the presentation of the in...
Christine Marie George, Shirajum Monira, Fatema Zohura, Elizabeth Thomas et al.
BACKGROUND: The Cholera Hospital-Based Intervention for 7 Days (CHoBI7) mobile health (mHealth) program was a cluster-randomized controlled trial of diarrhea patient households conducted in Dhaka, Bangladesh. METHODS: Patients were block-randomized to 3 arms: standard message on oral rehydration sol...
Christine Marie George, Danielle Jung, KM Saif‐Ur‐Rahman, Shirajum Monira et al.
Diarrhea is the second leading cause of death in children under 5 years of age globally. The time patients and caregivers spend at a health facility for severe diarrhea presents the opportunity to deliver water, sanitation, and hygiene (WASH) interventions. We recently developed Cholera-Hospital-Bas...
Christine Marie George, Khaled Hasan, Shirajum Monira, Zillur Rahman et al.
BACKGROUND: Household contacts of cholera patients are at a 100 times higher risk of developing cholera than the general population. The objective of this study was to examine the incidence of V. cholerae infections among household contacts of cholera patients in a rural setting in Bangladesh, to id...
Vanessa Burrowes, Jamie Perin, Shirajum Monira, David A. Sack et al.
Household contacts of cholera patients are at a 100 times higher risk of a Vibrio cholerae infection than the general population. To examine risk factors for V. cholerae infections and investigate intervention strategies among this population, we followed household contacts of cholera patients for t...
Mahamud‐ur Rashid, Christine Marie George, Shirajum Monira, Toslim Mahmud et al.
Abstract Household members of cholera patients are at a 100 times higher risk of cholera infections than the general population because of shared contaminated drinking water sources and secondary transmission through poor household hygiene practices. In this study, we investigated the bactericidal c...
Zillur Rahman, Aminul Islam, Mahamud‐ur Rashid, Fatema‐Tuz Johura et al.
Of 19 environmental Escherichia coli (n = 12) and Klebsiella pneumoniae (n = 7) tested for quinolone resistance-related genes qnrA, qnrB, qnrC, qnrS and qepA, four each of E. coli and K. pneumoniae possessed qnrS, and another E. coli isolate possessed a new variant of qepA. This is the first detecti...
Mahamud‐ur Rashid, Shah M. Rashed, Mohammad Tarequl Islam, Fatema‐Tuz Johura et al.
Microbiology Society journals contain high-quality research papers and topical review articles. We are a not-for-profit publisher and we support and invest in the microbiology community, to the benefit of everyone. This supports our principal goal to develop, expand and strengthen the networks avail...
Christine Marie George, Mahamud‐ur Rashid, Mathieu Almeida, KM Saif‐Ur‐Rahman et al.
BACKGROUND: Household contacts of cholera patients have a 100 times higher risk of developing a cholera infection than the general population. To compare the genetic relatedness of clinical and water source Vibrio cholerae isolates from cholera patients' households across three outbreaks, we analyze...
Shah M. Rashed, Anwarul Iqbal, Shahnewaj Bin Mannan, Mohammad Tarequl Islam et al.
To the Editor. Cholera, caused by Vibrio cholerae, continues to affect millions of persons in disease-endemic areas where safe drinking water is scarce and sanitation is poor. Of 7 cholera pandemics recorded since 1817, V. cholerae serogroup O1 classical (CL) biotype was associated with the sixth, w...