Stephanie W. Lo, Kate C. Mellor, Robert Cohen, Alba Redin Alonso et al.
BACKGROUND: Serotype 24F is one of the emerging pneumococcal serotypes after the introduction of pneumococcal conjugate vaccine (PCV). We aimed to identify lineages driving the increase of serotype 24F in France and place these findings into a global context. METHODS: Whole-genome sequencing was per...
Martin Beal, Maria P. Dias, Richard A. Phillips, Steffen Oppel et al.
Migratory marine species cross political borders and enter the high seas, where the lack of an effective global management framework for biodiversity leaves them vulnerable to threats. Here, we combine 10,108 tracks from 5775 individual birds at 87 sites with data on breeding population sizes to est...
List of figures List of maps List of tables Notes on contributors Preface Introduction: themes in the study of the South Asian diaspora Colin Clarke, Ceri Peach and Steven Vertovec Part I. South Asians in Colonial and Post-Colonial Contexts: Introduction Colin Clarke, Ceri Peach and Steven Vertovec ...
Joshua C D'Aeth, Mark PG van der Linden, Lesley McGee, Hermı́nia de Lencastre et al.
Multidrug-resistant Streptococcus pneumoniae emerge through the modification of core genome loci by interspecies homologous recombinations, and acquisition of gene cassettes. Both occurred in the otherwise contrasting histories of the antibiotic-resistant S. pneumoniae lineages PMEN3 and PMEN9. A si...
Sophie Belman, Noémie Lefrancq, Susan Nzenze, Sarah Downs et al.
. The extent and mechanisms of spread and vaccine-driven changes in fitness and antimicrobial resistance remain largely unquantified. Here using geolocated genome sequences from South Africa (n = 6,910, collected from 2000 to 2014), we developed models to reconstruct spread, pairing detailed human m...
C. A. Beale, Fabien Paulot, Cynthia A. Randles, Rui Wang et al.
Abstract Ammonia (NH 3 ) is a key precursor of haze particles and fine particulate matter (PM 2.5 ) and its spatiotemporal variabilities are poorly constrained. In this study, we present measurements of NH 3 over the Indian subcontinent region from the Infrared Atmospheric Sounder Interferometer (IA...
Stephanie W. Lo, Rebecca A. Gladstone, Andries J. van Tonder, Mignon du Plessis et al.
OBJECTIVES: We reported tet(S/M) in Streptococcus pneumoniae and investigated its temporal spread in relation to nationwide clinical interventions. METHODS: We whole-genome sequenced 12 254 pneumococcal isolates from 29 countries on an Illumina HiSeq sequencer. Serotype, multilocus ST and antibiotic...
Kedibone Ndlangisa, Mignon du Plessis, Stephanie W. Lo, Linda de Gouveia et al.
Pneumococcal serotype 35B is an important non-conjugate vaccine (non-PCV) serotype. Its continued emergence, post-PCV7 in the USA, was associated with expansion of a pre-existing 35B clone (clonal complex [CC] 558) along with post-PCV13 emergence of a non-35B clone previously associated with PCV ser...
Taj Azarian, Patrick K. Mitchell, Maria Georgieva, Claudette M. Thompson et al.
Abstract Streptococcus pneumoniae serotype 3 remains a significant cause of morbidity and mortality worldwide, despite inclusion in the 13-valent pneumococcal conjugate vaccine (PCV13). Serotype 3 increased in carriage since the implementation of PCV13 in the United States, while invasive disease ra...
Udaya R. Waglé
Abstract Electoral participation is the most dominant form of political participation. When it comes to influencing policy outcomes, however, other forms are also important. This paper examines the extent of electoral and other forms of political participation in Kathmandu and finds that both approa...
Stephanie W. Lo, Rebecca A. Gladstone, Andries J. van Tonder, Mignon du Plessis et al.
Synopsis Objective We reported a novel tetracycline-resistant gene in Streptococcus pneumoniae and investigated its temporal spread in relation to nationwide clinical interventions. Methods We whole genome sequenced 12,254 pneumococcal isolates from twenty-nine countries on an Illumina HiSeq Sequenc...
Joshua C D'Aeth, Mark PG van der Linden, Lesley McGee, Hermı́nia de Lencastre et al.
Selection by national-level antibiotic consumption and vaccination trends drives atypical recombinations, frequently resulting in interspecies sequence exchange at many sites across a bacterial species’ chromosome.