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Results for “"Md. Nazim Uddin Chy"”

16+ results

Investigation of the Biological Activities and Characterization of Bioactive Constituents of Ophiorrhiza rugosa var. prostrata (D.Don) & Mondal Leaves through In Vivo, In Vitro, and In Silico Approaches

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Md. Adnan, Md. Nazim Uddin Chy, A.T.M. Mostafa Kamal, Md Obyedul Kalam Azad et al.

Journal: MoleculesYear: 2019Citations: 132

Ophiorrhiza rugosa var. prostrata is one of the most frequently used ethnomedicinal plants by the indigenous communities of Bangladesh. This study was designed to investigate the antidiarrheal, anti-inflammatory, anthelmintic and antibacterial activities of the ethanol extract of O. rugosa leaves (E...

Life SciencesAgricultural and Biological SciencesPlant ScienceOpen Access
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Central and peripheral pain intervention by Ophiorrhiza rugosa leaves: Potential underlying mechanisms and insight into the role of pain modulators

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Md. Nazim Uddin Chy, Md. Adnan, Md. Riad Chowdhury, Ester Pagano et al.

Journal: Journal of EthnopharmacologyYear: 2021Citations: 100

ETHNOPHARMACOLOGICAL RELEVANCE Ophiorrhiza rugosa var.prostratais a traditional medicinal plant used by the indigenous and local tribes (Chakma, Marma and Tanchangya) of Bangladesh for the management of chest pain, body ache, and earache. However, the knowledge of anti-nociceptive and anti-inflammat...

Life SciencesPharmacology, Toxicology and PharmaceuticsPharmacology
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Biochemical and Computational Approach of Selected Phytocompounds from Tinospora crispa in the Management of COVID-19

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Ahmed Rakib, Arkajyoti Paul, Md. Nazim Uddin Chy, Saad Ahmed Sami et al.

Journal: MoleculesYear: 2020Citations: 96

A pandemic caused by the novel coronavirus (SARS-CoV-2 or COVID-19) began in December 2019 in Wuhan, China, and the number of newly reported cases continues to increase. More than 19.7 million cases have been reported globally and about 728,000 have died as of this writing (10 August 2020). Recently...

Health SciencesMedicineComplementary and alternative medicineOpen Access
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GC-MS Phytochemical Profiling, Pharmacological Properties, and In Silico Studies of Chukrasia velutina Leaves: A Novel Source for Bioactive Agents

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Israt Jahan, Marzia Rahman Tona, Sanjida Sharmin, Mohammed Aktar Sayeed et al.

Journal: MoleculesYear: 2020Citations: 65

Chukrasia velutina is a local medicinal plant commonly known as chikrassy in Bangladesh, India, China, and other South Asian countries. The leaves, bark, and seeds are vastly used as herbal medicine for fever and diarrhea, and its leaves essential oils are used for antimicrobial purposes. In this st...

Life SciencesAgricultural and Biological SciencesPlant ScienceOpen Access
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Investigation of the Pharmacological Properties of Lepidagathis hyalina Nees through Experimental Approaches

Verified

Fowzul Islam Fahad, Niloy Barua, Md. Shafiqul Islam, Syed Al Jawad Sayem et al.

Journal: LifeYear: 2021Citations: 61

Lepidagathis hyalina Nees is used locally in Ayurvedic medicine to treat coughs and cardiovascular diseases. This study explored its pharmacological potential through in vivo and in vitro approaches for the metabolites extracted (methanolic) from the stems of L. hyalina. A qualitative phytochemical ...

Health SciencesMedicineComplementary and alternative medicineOpen Access
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Evaluation of anti-nociceptive and anti-inflammatory activities of the methanol extract of Holigarna caustica (Dennst.) Oken leaves

Verified

Md. Adnan, Md. Nazim Uddin Chy, A.T.M. Mostafa Kamal, James W. Barlow et al.

Journal: Journal of EthnopharmacologyYear: 2019Citations: 54

ETHNOPHARMACOLOGICAL RELEVANCE Holigarna caustica (Dennst.) is commonly used in traditional medicine to treat a variety of painful conditions such as eye irritation, inflammation, arthritis, skin diseases, cuts and wounds. AIM OF THE STUDY The present study was undertaken to investigate the anti-noc...

Life SciencesAgricultural and Biological SciencesPlant ScienceOpen Access
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In vivo and in vitro pharmacological activities of Tacca integrifolia rhizome and investigation of possible lead compounds against breast cancer through in silico approaches

Verified

Shahriar Ahmed, Ahmed Rakib, Md. Ashiqul Islam, Bibi Humayra Khanam et al.

Journal: Clinical PhytoscienceYear: 2019Citations: 52

Abstract Background The study was conducted to evaluate the analgesic, anti-inflammatory, antipyretic properties of ethanolic extract of Tacca integrifolia rhizome (EETI) in mice and cytotoxic effects in brine shrimp nauplii followed by a PASS prediction study for some isolated compounds of T. integ...

Life SciencesBiochemistry, Genetics and Molecular BiologyMolecular BiologyOpen Access
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Intervention in Neuropsychiatric Disorders by Suppressing Inflammatory and Oxidative Stress Signal and Exploration of In Silico Studies for Potential Lead Compounds from Holigarna caustica (Dennst.) Oken leaves

Verified

Md. Adnan, Md. Nazim Uddin Chy, A.T.M. Mostafa Kamal, Kazi Ashfak Ahmed Chowdhury et al.

Journal: BiomoleculesYear: 2020Citations: 50

Holigarna caustica (Dennst.), a popular plant used in folk medicine in Bangladesh, is often used by the local folk practitioner to treat a variety of chronic diseases. The present research is an attempt to find out an innovative therapeutic prospect for the management of neuropsychiatric disorders. ...

Life SciencesAgricultural and Biological SciencesPlant ScienceOpen Access
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Network Pharmacology Study to Reveal the Potentiality of a Methanol Extract of Caesalpinia sappan L. Wood against Type-2 Diabetes Mellitus

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Md. Adnan, Byeong-Bae Jeon, Md. Helal Uddin Chowdhury, Ki‐Kwang Oh et al.

Journal: LifeYear: 2022Citations: 35

L. (CS) is widely used to treat diabetic complications in south-east Asia, specifically in traditional Chinese medicine. This study intends to explain the molecular mechanism of how chemical constituents of CS interrelate with different signaling pathways and receptors involved in T2DM. GC-MS was em...

Health SciencesMedicinePharmacologyOpen Access
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An integrated exploration of pharmacological potencies of Bischofia javanica (Blume) leaves through experimental and computational modeling

Verified

Md. Riad Chowdhury, Kamrul Hasan Chowdhury, Nujhat Binte Hanif, Mohammed Abu Sayeed et al.

Journal: HeliyonYear: 2020Citations: 31

, which can be a potential candidate in the food and pharmaceutical industries.

Life SciencesBiochemistry, Genetics and Molecular BiologyMolecular BiologyOpen Access
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An Internet of Things (IoT) based Smart Traffic Management System: A Context of Bangladesh

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Abdul Kadar Muhammad Masum, Md. Kalim Amzad Chy, Iaamanur Rahman, Mohammad Nazim Uddin et al.

Year: 2018Citations: 31

With the fast growth of population, traffic congestion monitoring and control has become a great challenge. Increasing vehicles creates lots of problem like time wastage, fuel wastage, air and sound pollution, even death by getting stuck emergency vehicles. This paper proposes a real-time traffic ma...

Physical SciencesEngineeringBuilding and Construction
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Pharmacological studies on the antinociceptive, anxiolytic and antidepressant activity of <i>Tinospora crispa</i>

Verified

Ahmed Rakib, Shahriar Ahmed, Md. Ashiqul Islam, Mir Muhammad Nasir Uddin et al.

Journal: Phytotherapy ResearchYear: 2020Citations: 30

Pharmacological studies were performed in mice on the methanol extract of Tinospora crispa (TC), and of its hexane (HF) and chloroform (CF) fractions. Significant antinociceptive activity was observed for TC, HF, and CF in the acetic acid-induced writhing and formalin-induced paw licking tests. Anxi...

Health SciencesMedicineComplementary and alternative medicineOpen Access
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Unveiling Pharmacological Responses and Potential Targets Insights of Identified Bioactive Constituents of Cuscuta reflexa Roxb. Leaves through In Vivo and In Silico Approaches

Verified

Md. Adnan, Md. Nazim Uddin Chy, A.T.M. Mostafa Kamal, Md. Riad Chowdhury et al.

Journal: PharmaceuticalsYear: 2020Citations: 29

Cuscuta reflexa Roxb. is traditionally used by the indigenous communities of Bangladesh to treat different diseases, such as pain, edema, tumor, jaundice, and skin infections. This study tested neuro-pharmacological, anti-nociceptive, and antidiarrheal activities by in vivo and in silico experiments...

Life SciencesAgricultural and Biological SciencesFood ScienceOpen Access
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Anthelmintic activity of Piper sylvaticum Roxb. (family: Piperaceae): In vitro and in silico studies

Verified

Arkajyoti Paul, Md. Adnan, Mohuya Majumder, Niloy Kar et al.

Journal: Clinical PhytoscienceYear: 2018Citations: 29

The present study was conducted to investigate the anthelmintic activity of methanol extract of Piper sylvaticum stem (MEPSS) in experimental model followed by in silico molecular docking study and ADME/T analysis. Anthelmintic activity was determined by an aquarium worm (Tubifex tubifex). Then, mol...

Life SciencesPharmacology, Toxicology and PharmaceuticsPharmacologyOpen Access
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In Vitro and In Vivo Biological Activities of Cissus adnata (Roxb.)

Verified

Mohammed Shoibe, Md. Nazim Uddin Chy, Morshed Alam, Md. Adnan et al.

Journal: BiomedicinesYear: 2017Citations: 25

This study was conducted to evaluate the in vitro polyphenol content, antioxidant, cytotoxic, antibacterial, anthelmintic properties, and in vivo antinociceptive activity of the ethanol extract of Cissus adnata leaves (EECA) in different experimental models. Polyphenol contents were investigated usi...

Life SciencesAgricultural and Biological SciencesPlant ScienceOpen Access
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