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Results for “"Md. Sahab Uddin"”

16+ results

Role of Phenolic Compounds in Human Disease: Current Knowledge and Future Prospects

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Md. Mominur Rahman, Md. Saidur Rahaman, Md. Rezaul Islam, Firoza Rahman et al.

Journal: MoleculesYear: 2021Citations: 797

Inflammation is a natural protective mechanism that occurs when the body's tissue homeostatic mechanisms are disrupted by biotic, physical, or chemical agents. The immune response generates pro-inflammatory mediators, but excessive output, such as chronic inflammation, contributes to many persistent...

Health SciencesMedicineBiochemistryOpen Access
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Autophagy and Alzheimer’s Disease: From Molecular Mechanisms to Therapeutic Implications

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Md. Sahab Uddin, Anna Stachowiak, Abdullah Al Mamun, Nikolay Tzvetkov et al.

Journal: Frontiers in Aging NeuroscienceYear: 2018Citations: 457

Alzheimer’s disease (AD) is the most common cause of progressive dementia in the elderly. It is characterized by a progressive and irreversible loss of cognitive abilities and formation of senile plaques, composed mainly of amyloid β (Aβ), and neurofibrillary tangles (NFTs), composed of tau protein,...

Health SciencesMedicineEpidemiologyOpen Access
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Nanoparticles and its biomedical applications in health and diseases: special focus on drug delivery

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Nuzhat Zahin, Raihanatul Anwar, Devesh Tewari, Md. Tanvir Kabir et al.

Journal: Environmental Science and Pollution ResearchYear: 2019Citations: 366

Nanotechnology is an emerging technology that deals with nanosized particles possessing crucial research roles and application. Disciplines like chemistry, biology, physics, engineering, materials science, and health sciences provide an accumulated knowledge of nanotechnology. Nonetheless, it has va...

Physical SciencesMaterials ScienceBiomaterials
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Taurine and its analogs in neurological disorders: Focus on therapeutic potential and molecular mechanisms

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Md. Jakaria, Shofiul Azam, Md. Ezazul Haque, Song-Hee Jo et al.

Journal: Redox BiologyYear: 2019Citations: 302

Taurine is a sulfur-containing amino acid and known as semi-essential in mammals and is produced chiefly by the liver and kidney. It presents in different organs, including retina, brain, heart and placenta and demonstrates extensive physiological activities within the body. In the several disease m...

Life SciencesBiochemistry, Genetics and Molecular BiologyCell BiologyOpen Access
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Molecular mechanisms underlying protective role of quercetin in attenuating Alzheimer's disease

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Elizabeta Zaplatić, Mohammed Hussen Bule, Syed Zahid Ali Shah, Md. Sahab Uddin et al.

Journal: Life SciencesYear: 2019Citations: 289

Quercetin belongs to the flavonoids family, which is present in most of the plants including fruits, vegetables, green tea and even in red wine having antioxidant activities. It is available as a food supplement in the market and has physiological health effects. Quercetin has anti-inflammatory, ant...

Life SciencesBiochemistry, Genetics and Molecular BiologyClinical Biochemistry
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Dendrimers: A New Race of Pharmaceutical Nanocarriers

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Pooja Mittal, Anjali Saharan, Ravinder Verma, Farag M. A. Altalbawy et al.

Journal: BioMed Research InternationalYear: 2021Citations: 242

Dendrimers are nanosized, symmetrical molecules in which a small atom or group of atoms is surrounded by the symmetric branches known as dendrons. The structure of dendrimers possesses the greatest impact on their physical and chemical properties. They grow outwards from the core-shell which further...

Physical SciencesMaterials SciencePolymers and PlasticsOpen Access
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Magnetic nanoparticles for hyperthermia in cancer treatment: an emerging tool

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Jobin Jose, Rajesh Kumar, Seetha Harilal, Githa Elizabeth Mathew et al.

Journal: Environmental Science and Pollution ResearchYear: 2019Citations: 232

Cancer remains as the major cause of death worldwide. The main reason why available therapies fail is that a vicious cycle in established which initiates multiple pathways and recurrence after metastasis. Hyperthermic treatment, which involves heating tumor tissues to a moderate temperature of 40-43...

Physical SciencesMaterials ScienceBiomaterials
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Epigenetics of glioblastoma multiforme: From molecular mechanisms to therapeutic approaches

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Md. Sahab Uddin, Abdullah Al Mamun, Badrah S. Alghamdi, Devesh Tewari et al.

Journal: Seminars in Cancer BiologyYear: 2020Citations: 221

Glioblastoma multiforme (GBM) is the most common form of brain cancer and one of the most aggressive cancers found in humans. Most of the signs and symptoms of GBM can be mild and slowly aggravated, although other symptoms might demonstrate it as an acute ailment. However, the precise mechanisms of ...

Life SciencesBiochemistry, Genetics and Molecular BiologyMolecular Biology
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APOE and Alzheimer’s Disease: Evidence Mounts that Targeting APOE4 may Combat Alzheimer’s Pathogenesis

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Md. Sahab Uddin, Md. Tanvir Kabir, Abdullah Al Mamun, Mohamed M. Abdel‐Daim et al.

Journal: Molecular NeurobiologyYear: 2018Citations: 221

Alzheimer's disease (AD) is an immutable neurodegenerative disease featured by the two hallmark brain pathologies that are the extracellular amyloid ß (Aß) and intraneuronal tau protein. People carrying the APOE4 allele are at high risk of AD concerning the ones carrying the ε3 allele, while the ε2 ...

Health SciencesMedicinePhysiology
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Combination Drug Therapy for the Management of Alzheimer’s Disease

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Md. Tanvir Kabir, Md. Sahab Uddin, Abdullah Al Mamun, Philippe Jeandet et al.

Journal: International Journal of Molecular SciencesYear: 2020Citations: 210

Alzheimer's disease (AD) is the leading cause of dementia worldwide. Even though the number of AD patients is rapidly growing, there is no effective treatment for this neurodegenerative disorder. At present, implementation of effective treatment approaches for AD is vital to meet clinical needs. In ...

Health SciencesMedicinePharmacologyOpen Access
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Synthesis and Toxicity of Graphene Oxide Nanoparticles: A Literature Review of <i>In Vitro</i> and <i>In Vivo</i> Studies

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Asmaa Rhazouani, Halima Gamrani, Mounir El Achaby, Khalid Aziz et al.

Journal: BioMed Research InternationalYear: 2021Citations: 207

Nanomaterials have been widely used in many fields in the last decades, including electronics, biomedicine, cosmetics, food processing, buildings, and aeronautics. The application of these nanomaterials in the medical field could improve diagnosis, treatment, and prevention techniques. Graphene oxid...

Physical SciencesEngineeringBiomedical EngineeringOpen Access
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Honokiol: A review of its pharmacological potential and therapeutic insights

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Abdur Rauf, Ahmed Olatunde, Muhammad Imran, Fahad A. Alhumaydhi et al.

Journal: PhytomedicineYear: 2021Citations: 180

Background Honokiol is a pleiotropic compound which been isolated from Magnolia species such as Magnolia grandiflora and Magnolia dealbata. Magnolia species Magnolia grandiflora is used in traditional medicine for the treatment of various diseases. Purpose The objective of this review is to summariz...

Health SciencesMedicineRehabilitation
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Potential health benefits of carotenoid lutein: An updated review

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Saikat Mitra, Abdur Rauf, Abu Montakim Tareq, Shamima Jahan et al.

Journal: Food and Chemical ToxicologyYear: 2021Citations: 178

Carotenoids in food substances are believed to have health benefits by lowering the risk of diseases. Lutein, a carotenoid compound, is one of the essential nutrients available in green leafy vegetables (kale, broccoli, spinach, lettuce, and peas), along with other foods, such as eggs. As nutrition ...

Health SciencesMedicineBiochemistry
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Circadian and sleep dysfunction in Alzheimer’s disease

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Md. Sahab Uddin, Devesh Tewari, Abdullah Al Mamun, Md. Tanvir Kabir et al.

Journal: Ageing Research ReviewsYear: 2020Citations: 176

Alzheimer's disease (AD) is a devastating and irreversible cognitive impairment and the most common type of dementia. Along with progressive cognitive impairment, dysfunction of the circadian rhythms also play a pivotal role in the progression of AD. A mutual relationship among circadian rhythms, sl...

Life SciencesNeuroscienceEndocrine and Autonomic SystemsOpen Access
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Nutraceuticals in Neurological Disorders

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Rashita Makkar, Tapan Behl, Simona Bungău, Gökhan Zengin et al.

Journal: International Journal of Molecular SciencesYear: 2020Citations: 174

Neurological diseases are one of the major healthcare issues worldwide. Posed lifestyle changes are associated with drastically increased risk of chronic illness and diseases, posing a substantial healthcare and financial burden to society globally. Researchers aim to provide fine treatment for aili...

Life SciencesBiochemistry, Genetics and Molecular BiologyMolecular BiologyOpen Access
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