Joshua N. Cobb, Roselyne U. Juma, P. Biswas, Juan David Arbelaez et al.
KEY MESSAGE: The integration of new technologies into public plant breeding programs can make a powerful step change in agricultural productivity when aligned with principles of quantitative and Mendelian genetics. The breeder's equation is the foundational application of quantitative genetics to cr...
Margo M. Wheatley, Sophie C. Silverstein, Michael Quinn, Leo Waterston et al.
The Institute of Medicine recently called for increased understanding of and commitment to timely care. Lung cancer can be difficult to diagnose, resulting in delays that may adversely affect survival; rapid diagnosis and treatment therefore is critical for enabling improved patient outcomes. This s...
Jessica C. Stark, Ally Huang, Peter Q. Nguyen, Rachel S. Dubner et al.
Synthetic biology offers opportunities for experiential educational activities at the intersection of the life sciences, engineering, and design. However, implementation of hands-on biology activities in classrooms is challenging because of the need for specialized equipment and expertise to grow li...
Axel Bruns, Anja Bechmann, Jean Burgess, Andrew Chadwick et al.
In reaction to the Cambridge Analytica controversy, Facebook has recently announced a substantial tightening of access restrictions to the APIs of Facebook, Instagram, and other platforms it owns. Researchers at leading international research organisations are deeply concerned about collateral impac...
Madhav Joshi, SungYong Lee, Roger Mac Ginty
AbstractThis article assesses the extent to which the liberal peace (the dominant form of internationally supported peacemaking) actually deserves the sobriquet 'liberal peace'. In recent years, an intense debate emerged on this question as critics of the critique of the liberal peace have sought to...
Paula M. Gilmore, Nuala McCabe, Jennifer E. Quinn, Richard D. Kennedy et al.
BRCA1 has been implicated in a number of cellular processes, including transcriptional regulation, DNA damage repair, cell cycle arrest, and apoptosis. We identified mitogen-activated protein kinase (MAPK) kinase kinase 3 (MEKK3), an upstream regulator of the c-Jun NH(2)-terminal kinase/stress-activ...
Felix Achana, Stavros Petrou, Jason Madan, Kamran Khan et al.
BACKGROUND: The 'Prehospital Assessment of the Role of Adrenaline: Measuring the Effectiveness of Drug Administration In Cardiac Arrest' (PARAMEDIC2) trial showed that adrenaline improves overall survival, but not neurological outcomes. We sought to determine the within-trial and lifetime health and...
Mathew Seymour, Tomas Roslin, Jeremy R deWaard, Kate Perez et al.
Global biodiversity gradients are generally expected to reflect greater species replacement closer to the equator. However, empirical validation of global biodiversity gradients largely relies on vertebrates, plants, and other less diverse taxa. Here we assess the temporal and spatial dynamics of gl...
Stephanie Lovinsky‐Desir, Kyung Hwa Jung, Michael Montilla, James W. Quinn et al.
Abstract Rationale Physical activity while being exposed to high concentrations of air pollution may lead to greater inhalation of pollutant particles and gases. Thus, owing to features of the built city environment, specific locations where physical activity take place may put individuals at increa...
Leah M. Thornton Hampton, Dana Briggs Wyler, Bethanie Carney Almroth, Scott Coffin et al.
In 2021 the Toxicity of Microplastics Explorer (ToMEx, https://microplastics.sccwrp.org) was released as an open source, open access database and web application for microplastics toxicity. Since then, it has been utilized by the microplastic research community for the exploration, visualization, an...
Mathew Seymour, Tomas Roslin, Jeremy R deWaard, Kate Perez et al.
K. M. Murphy, Frances O’Brien, Michael Madden, John Collins et al.
Claire S. Teitelbaum, Diann J. Prosser, Joshua T. Ackerman, Sakib Ahmed et al.
Animal movements contribute to the spread of infectious diseases and are driven in part by environmental conditions. We investigated the links among the environment, animal movement, and infectious disease dynamics in waterfowl, which are among the primary wildlife hosts of avian influenza viruses. ...
Mathew Seymour, Tomas Roslin, Jeremy R deWaard, Kate Perez et al.
Aim: Global gradients in species biodiversity may or may not be associated with greater species replacement closer to the equator. Yet, empirical validation of these patterns has so far focused on less diverse taxa, with comparable assessments of mega-diverse groups historically constrained by the t...
Andrea Rainey, Karen Cairns, A.H. Marshall, Michael Quinn et al.
The aim of this paper is to use Markov modelling to investigate survival for particular types of kidney patients in relation to their exposure to anti-hypertensive treatment drugs. In order to monitor kidney function an intuitive three point assessment is proposed through the collection of blood sam...