Mohamed Bnouham, Abdelkhaleq Legssyer, Hassane Mekhfi, Abderrahim Ziyyat
The present review shows a listing of medicinal plants used in phytotherapy of diabetes and those experimentally studied as hypoglycaemic in Morocco. The review is presented as 3 tables. The first one includes the taxonomic classification of the plant, the popular names in Morocco, the parts used, t...
M. Haouari, Mohamed Bnouham, Mourad Bendahou, Mohammed Aziz et al.
Platelet hyperactivity plays an important role in arterial thrombosis and atherosclerosis. The present study was undertaken to investigate the effects of different extracts of Urtica dioica leaves on platelet aggregation. Rat platelets were prepared and incubated in vitro with different concentratio...
Abdelkhaleq Legssyer, Abderrahim Ziyyat, Hassane Mekhfi, Mohamed Bnouham et al.
Urtica dioica L. or Nettle (Urticaceae) is widely used in oriental Morocco to treat hypertension. Aqueous extract of Nettle (AEN) also exerts a hypotensive action in the rat in vivo. The aim of this work was to characterize the specific cardiac and vascular effects of AEN. In the isolated Langendorf...
Dounia Gadi, Mohamed Bnouham, Mohammed Aziz, Abderrahim Ziyyat et al.
INTRODUCTION: Blood platelets are directly involved in both haemostatic and pathologic thrombotic processes, through their adhesion, secretion and aggregation. In this study, we investigated the effect of genins (aglycone flavonoids without sugar group) isolated from parsley (Petroselinum crispum) l...
Abdelkhaleq Legssyer, Abderrahim Ziyyat, Hassane Mekhfi, Mohamed Bnouham et al.
This study examined the vascular effect of Arbutus leaves (aqueous extract) and described the isolation of several fractions responsible for their vasorelaxant activity. The aqueous extract (AE) of leaves was tested on rat aortic rings precontracted with 0.1 microm noradrenaline. At 10(-2) g/L, AE p...
Abderrahim Ziyyat, Hassane Mekhfi, Mohamed Bnouham, Abdelhafid Tahri et al.
Arbutus unedo L. (Ericaceae) is used in oriental Morocco to treat arterial hypertension. We studied its vasodilator effect and mechanisms of action in vitro. The root aqueous extract of Arbutus (0.25 mg/mL) produced a relaxation of noradrenaline-precontracted ring preparations of rat aorta with inta...
Mohamed Marghich, Ouafa Amrani, Ahmed Karim, Tarik Harit et al.
ETHNOPHARMACOLOGICAL RELEVANCE Gastrointestinal disorders are among the most common diseases that cause discomfort to people who are affected. In Morocco, aromatic and medicinal plants are widely used to calm these pains and eliminate their symptoms. Among these plants, Artemisia campestris L. which...
Mounia Skiker, Hassane Mekhfi, Mohammed Aziz, Benyounès Haloui et al.
Artemisia herba-alba Asso (Compositae) is used in oriental Morocco to treat diabetes and arterial hypertension. The present work evaluated the vasorelaxant effect of Artemisia herba-alba aqueous extract (AHAE) in isolated rat aorta and the mechanism underlying this effect. In endothelium-containing ...
Amal Elrherabi, Mohamed Bouhrim, Rhizlan Abdnim, Ali Berraaouan et al.
BACKGROUND: Diabetes mellitus is a widespread metabolic disorder affecting global populations. Lavandula stoechas from Moroccan traditional medicine is used for its potential anti-diabetic effects. OBJECTIVE: This study aims to evaluate the antihyperglycemic impact of the aqueous extract of L. stoec...
Imane Ziani, Hamza Bouakline, Saliha Bouknana, Nour Eddine Bentouhami et al.
In agriculture, fragrant and medicinal plants offer untapped potential for biomass-derived materials, particularly within wastewater by-products. This study investigates the chemical compositions, antioxidant capacities, antimicrobial properties, acute oral toxicity, and diabetes management potentia...
Tarik Harit, Mounir Cherfi, Nour Elhouda Daoudi, Jalal Isaad et al.
Abstract The elaboration of some N‐alkylated pyrazole‐tetrazole derivatives is reported. The structures of the newly ones are verified using NMR and FTIR spectroscopies, mass spectrometry as well as elemental analysis. Their potencies to inhibit the α‐amylase enzyme were evaluated using spectrophoto...
Hamid Nouayti, Nourel Houda Bouanani, Jamila Hammoudi, Hassane Mekhfi et al.
BACKGROUND Overweight and obesity in children and adolescents have become a major public health problem affecting most countries worldwide. The purpose of the study was to assess the prevalence and risk factors of overweight and obesity among public high school students in Eastern Morocco. METHODS A...
Hamza Bouakline, Mohamed Brahmi, Imane Ziani, Abdnim Rhizlan et al.
Amal Elrherabi, Mohamed Bouhrim, Rhizlan Abdnim, Ali Berraaouan et al.
The aqueous extract of Lavandula stoechas (AqLs) is employed as a diabetic cure in Eastern Moroccan traditional medicine. The aim of this study was to confirm and search for the antidiabetic mechanisms of this plant. The goal of this research is to look into the in vitro antioxidant activity of L. s...
W Dahmani, Zachée Louis Evariste Akissi, Nabia El-aouni, Nour Elhouda Bouanani et al.
ETHNOPHARMACOLOGICAL RELEVANCE Ceratonia siliqua L., is a species of significant nutritional and industrial interest with extensive traditional uses. This fabaceae is renowned for its medicinal properties, including the treatment of high blood pressure. Due to its chemical composition, carob exhibit...