Mohammed Mahbubul Matin, Priyanka Matin, Md. Rezaur Rahman, Taïbi Ben Hadda et al.
Among the nitrogen-containing heterocyclic compounds, triazoles emerge with superior pharmacological applications. Structurally, there are two types of five-membered triazoles: 1,2,3-triazole and 1,2,4-triazole. Due to the structural characteristics, both 1,2,3- and 1,2,4-triazoles are able to acco..
Prabhakar Semwal, Sakshi Painuli, Tareq Abu‐Izneid, Abdur Rauf et al.
contain a lot of diosgenin, a steroidal sapogenin. This bioactive phytochemical has shown high potential and interest in the treatment of various disorders such as cancer, diabetes, arthritis, asthma, and cardiovascular disease, in addition to being an important starting material for the preparation...
Muhammad Torequl Islam, Cristina Quispe, Jesús Herrera‐Bravo, Chandan Kumar Sarkar et al.
Dengue remains one of the most serious and widespread mosquito‐borne viral infections in human beings, with serious health problems or even death. About 50 to 100 million people are newly infected annually, with almost 2.5 billion people living at risk and resulting in 20,000 deaths. Dengue virus in...
Rajib Hossain, Cristina Quispe, Jesús Herrera‐Bravo, Md. Shahazul Islam et al.
Lasia spinosa (L.) is used ethnobotanically for the treatment of various diseases, including rheumatoid arthritis, inflammation of the lungs, bleeding cough, hemorrhoids, intestinal diseases, stomach pain, and uterine cancer. This review is aimed at summarizing phytochemistry and pharmacological dat...
Khalid A. Bin Abdulrahman, Abdulrahman S Alshehri, Khalid M Alkhalifah, Ahmed B. Alasiri et al.
BACKGROUND: Motivation is the process whereby goal-directed activities are initiated and sustained. Motivation is a crucial factor in academic achievement. The study aims to measure students' demographic factors and external environments' effect on their motivation and determine the impact of studen...
Rajib Hossain, Cristina Quispe, Jesús Herrera‐Bravo, Jorge F. Beltrán et al.
(Burm.f.) Nees, possesses several biological effects such as antioxidant, anti-inflammatory, and organo-protective effects. Scientific reports suggest that it also has neuroprotective capacity in various test systems. The purpose of this review was to synthesize the neuropharmacological properties o...
B. S. Manya, M. R. Pradeep Kumar, Kalirajan Rajagopal, Md. Abul Hassan et al.
Pyrrole, with its versatile heterocyclic ring structure, serves as a valuable template for generating a diverse range of lead compounds with various pharmacophores. Researchers and scientists globally are intrigued by pyrrole and its analogs for their broad pharmacological potential, prompting thoro...
Haruna Isiyaku Umar, Adeola Ajayi, Nobendu Mukerjee, Abdullahi Tunde Aborode et al.
Heat shock protein 27 (HSP27) is a protein that works as a chaperone and an antioxidant and is activated by heat shock, environmental stress, and pathophysiological stress. However, HSP27 dysregulation is a characteristic of many human cancers. HSP27 suppresses apoptosis and cytoskeletal reorganizat...
Mst. Sharmin Sultana Shimu, Shafi Mahmud, Trina Ekawati Tallei, Saad Ahmed Sami et al.
The spread of the Dengue virus over the world, as well as multiple outbreaks of different serotypes, has resulted in a large number of deaths and a medical emergency, as no viable medications to treat Dengue virus patients have yet been found. In this paper, we provide an in silico virtual screening...
Biswajit Kumar Utpal, Fatima Zohra Mokhfi, Mehrukh Zehravi, Sherouk Hussein Sweilam et al.
Neurological diseases (NDs), including neurodegenerative disorders and acute injuries, are a significant global health concern. The PI3K/Akt/mTOR pathway, a crucial signaling cascade, is responsible for the survival of cells, proliferation, and metabolism. Dysregulation of this pathway has been link...
Biswajit Kumar Utpal, Baishakhi Sutradhar, Mehrukh Zehravi, Sherouk Hussein Sweilam et al.
Wound healing is a multifaceted, complex process that factors like aging, metabolic diseases, and infections may influence. The potentiality of polyphenols, natural compounds, has shown anti-inflammatory and antimicrobial properties in promoting wound healing and their potential applications in woun...
Divya Jain, Yogesh Murti, Wasi Ullah Khan, Rajib Hossain et al.
Hepatocellular carcinoma (HCC) is due to poor prognosis and lack of availability of effective treatment. Novel therapeutic strategies will be the fine tuning of intracellular ROS signaling to effectively deprive cells of ROS-induced tumor-promoting events. This review discusses the generation of ROS...
Md. Rezaul Islam, Md Al-Imran, Mehrukh Zehravi, Sherouk Hussein Sweilam et al.
BACKGROUND: Neurodegenerative diseases (NDs), including Alzheimer's disease, Parkinson's disease, and Huntington's disease, are complex and challenging due to their intricate pathophysiology and limited treatment options. METHODS: This review systematically sourced articles related to neurodegenerat...
Tatireddy Subba Reddy, Jonnadula Harikiran, Murali Krishna Enduri, Koduru Hajarathaiah et al.
The classification technology of hyperspectral images (HSI) consists of many contiguous spectral bands that are often utilized for a various Earth observation activities, such as surveillance, detection, and identification. The incorporation of both spectral and spatial characteristics is necessary ...
Shafi Mahmud, Suvro Biswas, Shamima Afrose, Mohasana Akter Mita et al.
Mitochondria are major contributors to ATP synthesis, generating more than 90% of the total cellular energy production through oxidative phosphorylation (OXPHOS): metabolite oxidation, such as the β-oxidation of fatty acids, and the Krebs's cycle. OXPHOS inadequacy due to large genetic lesions in mi...
Priyanka Maiti, Priyanka Sharma, Mahesha Nand, Indra D. Bhatt et al.
Among the various types of cancer, lung cancer is the second most-diagnosed cancer worldwide. The kinesin spindle protein, Eg5, is a vital protein behind bipolar mitotic spindle establishment and maintenance during mitosis. Eg5 has been reported to contribute to cancer cell migration and angiogenesi...
Md Zamshed Alam Begh, Jishan Khan, Md. Al Amin, Sherouk Hussein Sweilam et al.
Monoterpenoids, compounds found in various organisms, have diverse applications in various industries. Their effectiveness is influenced by the oil's chemical composition, which in turn is influenced by plant genotype, environmental conditions, cultivation practices, and plant development stage. The...
Rahul Kumar Sharma, Shabana Bibi, Hitesh Chopra, Muhammad Saad Khan et al.
Phytochemicals have been shown to possess multiple bioactives and have been reported to showcase many medicinal effects. A similar kind of evaluation of phytoconstituents for their antimicrobial action has been reported, based on in vitro and in silico data. The goal of the research was to explore b...
Md Zamshed Alam Begh, Jishan Khan, Mehrukh Zehravi, Sherouk Hussein Sweilam et al.
Neurological disorders (NDs) encompass a range of debilitating conditions that affect the nervous system, including prevalent illnesses such as Alzheimer's disease, Parkinson's disease, and ischemic stroke. Despite significant ongoing studies, effective therapeutic strategies to halt or slow down th...
Abu Reza Md. Towfiqul Islam, Md. Uzzal Mia, Nourin Akter Nova, Rabin Chakrabortty et al.
This article intends to assess flood susceptibility mapping in Meghna River basin (MRB) and identified flood susceptible regions using three benchmark models including random forest (RF), support vector machine (SVM) and bagging with Naïve Bayes (NB) stacking ensemble algorithms (e.g. RF-NB; SVM-NB ...