Maryam Zaid, Katsuyuki Miura, Akira Okayama, Hideaki Nakagawa et al.
BACKGROUND: Recently, high-density lipoprotein particles (HDL-P) have been found to be more strongly inversely associated with coronary artery disease (CAD) risk than their counterpart, HDL cholesterol (HDL-C). Given that lifestyle is among the first targets in CAD prevention, we compared the associ...
Yasuyuki Nakamura, Hirotsugu Ueshima, Nagako Okuda, Katsuyuki Miura et al.
Purpose Low-carbohydrate diets (LCD) are a popular dietary strategy for weight reduction. The effects of LCD on long-term outcome vary depending on type of LCD, possibly due to the fact that effects on cardiometabolic risk factors may vary with different types of LCD. Accordingly, we studied these r...
INTERMAP Study Group, Naoyuki Takashima, Takayoshi Ohkubo, Katsuyuki Miura et al.
Several studies demonstrated that visit-to-visit variability of blood pressure (BP) predicted future events of total death, stroke and cardiovascular disease. Little is known about factors associated with visit-to-visit BP variability in different countries. We recruited participants aged 40–59 year...
Yasuyuki Nakamura, Hirotsugu Ueshima, Nagako Okuda, Yoshitaka Murakami et al.
PurposeIt has been hypothesized that leptin-induced appetite suppression is impaired in obese individuals, but little human evidence is available documenting this. We investigated relations between serum leptin and total energy intake using INTERLIPID/INTERMAP data on Japanese–Americans in Hawaii an...
Yasuyuki Nakamura, Hirotsugu Ueshima, Nagako Okuda, Katsuyuki Miura et al.
Objective. Despite considerable study, the relevance of leptin and adiponectin for atherosclerosis development is still unsettled. We investigated relations of serum leptin and adiponectin to serum C-reactive protein (CRP), using the INTERLIPID dataset on Japanese emigrants living in Hawaii and Japa...
Yukiko Okami, Hirotsugu Ueshima, Yasuyuki Nakamura, Nagako Okuda et al.
AIM: The positive relationship between dietary cholesterol and serum cholesterol has been questioned by a set of recent cohort studies. This study aimed to investigate how employment status and education years relate to the association between dietary cholesterol and serum low-density lipoprotein ch...
Yukiko Okami, Hirotsugu Ueshima, Yasuyuki Nakamura, Nagako Okuda et al.
Introduction: The upper limit of recommended dietary cholesterol has been abolished recently from guidelines in Japan and US even though high intake is known to increase serum cholesterol levels. Reverse causality has been involved, reflecting availability of widespread information with consequent l...
Yasuyuki Nakamura, Hirotsugu Ueshima, Nagako Okuda, Katsuyuki Miura et al.
Introduction: Sizable numbers of people have tried low carbohydrate diets (LCD) of varied types; data are sparse on effects on cardiometabolic risk factors with different types of LCD. Hypothesis: We assessed the hypothesis that relationships of LCD score to cardiometabolic risk factors and an infla...
Maryam Zaid, Katsuyuki Miura, Akira Fujiyoshi, Akira Okayama et al.
Background: Studies have found that HDL particle (HDL-P) concentration is inversely associated with risk of CVD, independent of HDL cholesterol (HDL-C). Dietary factors (such as fatty acid intake) have been found to affect levels of HDL-C and influence risk of CVD. However, little is known about the...