Jan Bonhoeffer, Egeruan B. Imoukhuede, Grace M. Aldrovandi, Novilia Sjafri Bachtiar et al.
This document is intended as a guide to the protocol development for trials of prophylactic vaccines. The template may serve phases I-IV clinical trials protocol development to include safety relevant information as required by the regulatory authorities and as deemed useful by the investigators. Th...
Peter Rigsby, Emma Beamish, Jason Hockley, Eleanor Atkinson et al.
Typhoid vaccines based on protein-conjugated capsular Vi polysaccharide (TCVs) prevent typhoid in infants and young children. Analysis of the serum anti-Vi IgG response following immunisation against typhoid confirms the immunogenicity of TCVs and forms an important part of the pathway to licensing....