Paul A. Griffin, Arnold M. Wright
The commentaries in this forum on Big Data confront one of our profession’s most pressing challenges. How should we respond to Big Data? Big Data and business analytics now permeate almost all aspects of major companies’ decision making and business strategies. A large U.S. company, for example, mig...
Megan E. Carey, Zoe A. Dyson, Danielle J. Ingle, Afreenish Amir et al.
Background: serovar Typhi (Typhi) genomic data to inform public health action. This analysis, which marks 22 years since the publication of the first Typhi genome, represents the largest Typhi genome sequence collection to date (n=13,000). Methods: This is a meta-analysis of global genotype and anti...
Jonathan Shenfine, Paul McNamee, Nick Steen, J Bond et al.
OBJECTIVES: To compare whether treatment with self-expanding metal stents (SEMS) is more cost-effective than treatment with conventional modalities in patients with inoperable oesophageal cancer. Quality of life effects were also considered. DESIGN: A multicentre pragmatic, randomised controlled tri...
Sanzida Murshed, Amy L. Griffin, Md. Ashraful Islam, Xiao Hua Wang et al.
This study developed a geo-spatial framework for assessing multi-hazard threat on the Bangladesh coast, integrating environmental hazards (EH), geo-environmental attributes (GA), and anthropogenic modifications (AM) based on their potential contribution to overall threat. For this purpose, a fuzzy l...
Md Ashraful Islam, David J. Paull, Amy L. Griffin, Sanzida Murshed
Ecosystem services are essential for the livelihoods of marginalized communities; however, their supply can be severely disturbed when natural hazards impact on low-lying coastal regions. To understand potential disaster impacts on sustainable livelihoods, ecosystem resilience needs to be assessed b...
Sanzida Murshed, David J. Paull, Amy L. Griffin, Md. Ashraful Islam
Climate-change-induced disaster risks impede sustainable development goals in many developing countries. With the prevailing climate change conditions, environmental events are likely to become even more pervasive. Coastal regions, the source of numerous tangible and intangible benefits for human po...
Alexandra Valsamakis, Paul G. Auwaerter, B. K. Rima, Hideto Kaneshima et al.
To understand the molecular determinants of measles virus (MV) virulence, we have used the SCID-hu thymus/liver xenograft model (SCID-hu thy/liv) in which in vivo MV virulence phenotypes are faithfully duplicated. Stromal epithelial and monocytic cells are infected by MV in thymus implants, and viru...
Md Ashraful Islam, David J. Paull, Amy L. Griffin, Sanzida Murshed
Tropical cyclones wreak havoc on the lives of coastal populations, especially in marginalised communities in developing countries where cyclone impacts are disproportionately lethal compared to developed countries. These populations must implement measures that enable them to prepare for, respond to...
Sanzida Murshed, Amy L. Griffin, Md Ashraful Islam, Xiao Hua Wang et al.
Climate-related disasters have become a major threat to human civilization. Since many climatic hazards cannot be prevented, recognizing the underlying factors that render societies more vulnerable might facilitate pragmatic measures for minimizing the likelihood of disasters. With this impulse, the...
Md Ashraful Islam, Amy L. Griffin, David J. Paull, Sanzida Murshed
Lack of adequate infrastructure, especially in the coastal regions of developing countries, limits the capacity of households to prevent, cope with, and recover from the adverse effects of natural hazards. The services provided by critical infrastructure (CI) contribute to the overall resilience of ...
Sanzida Murshed, Amy L. Griffin, Md Ashraful Islam, Thomas S.N. Oliver et al.
Megan E. Carey, Zoe A. Dyson, Danielle J. Ingle, Afreenish Amir et al.
Abstract The Global Typhoid Genomics Consortium was established to bring together the typhoid research community to aggregate and analyse Salmonella enterica serovar Typhi (Typhi) genomic data to inform public health action. This analysis, which marks twenty-one years since the publication of the fi...
J. McAleese, K. Drinkwater, A. Bedair, Anthony Williams et al.
AIMS The Royal College of Radiologists (RCR) audit of radical radiotherapy (RR) for patients with non-small cell lung cancer (NSCLC) in 2013 concluded that there was under-treatment compared to international comparators and marked variability between cancer networks. Elderly patients were less likel...
Megan E. Carey, Zoe A. Dyson, Danielle J. Ingle, Afreenish Amir et al.
An analysis of the largest Salmonella Typhi genome collection to date (n=13,000) provides an updated overview of global genome diversity and antimicrobial resistance trends over time to inform public health action.
H. Al Sharida, M. Holohan, Matthew Hogan, Paulo Cézar de Freitas Mathias et al.