Habibul Ahsan, Mary Perrin, Mohammed Atiqur Rahman, Faruque Parvez et al.
The present study examined the associations between drinking water and urinary arsenic levels and skin lesions among 167 residents of three contiguous villages in Bangladesh. Thirty-six (21.6%) had skin lesions (melanosis, hyperkeratosis, or both), of which 13 (36.1%) occurred in subjects who were c...
Yu Chen, Pam Factor‐Litvak, Geoffrey R. Howe, Joseph H. Graziano et al.
The authors performed a cross-sectional analysis to evaluate the association between arsenic exposure from drinking water and blood pressure using baseline data of 10,910 participants in the Health Effects of Arsenic Longitudinal Study in Bangladesh (October 2000-May 2002). A time-weighted well arse...
F. Parvez, Yu Chen, Paul W. Brandt‐Rauf, Vesna Slavkovich et al.
BACKGROUND AND AIMS: A prospective cohort study was conducted to evaluate the effect of arsenic (As) exposure from drinking water on respiratory symptoms using data from the Health Effects of Arsenic Exposure Longitudinal Study (HEALS), a large prospective cohort study established in Ariahazar, Bang...
Faruque Parvez, Yu Chen, Paul W. Brandt‐Rauf, Alfred Bernard et al.
BACKGROUND: Arsenic from drinking water has been associated with malignant and nonmalignant respiratory illnesses. The association with nonmalignant respiratory illnesses has not been well established because the assessments of respiratory symptoms may be influenced by recall bias or interviewer bia...
Julia E. Heck, Jeri W. Nieves, Yu Chen, Faruque Parvez et al.
BACKGROUND: In Bangladesh, millions of people are exposed to arsenic in drinking water; arsenic is associated with increased risk of cancer. Once ingested, arsenic is metabolized via methylation and excreted in urine. Knowledge about nutritional factors affecting individual variation in methylation ...
Julia E. Heck, Jeri W. Nieves, Yu Chen, Faruque Parvez et al.
BACKGROUND: Few studies have described protein and amino acid intakes in rural Bangladesh, a country with considerable undernutrition. OBJECTIVE: The purpose of this population-based study was to assess and describe protein and amino acid intakes in Araihazar, Bangladesh. METHODS: The study particip...
Y. Li, Yu Chen, Vesna Slavkovic, Habibul Ahsan et al.
Epidermal growth factor receptor-dependent mechanisms have been implicated in growth signal transduction pathways that contribute to cancer development, including dermal carcinogenesis. Detection of the extracellular domain of the epidermal growth factor receptor (EGFR ECD) in serum has been suggest...
Do TAMARA, Angela Gambelunghe, GAMBELUNGHE AHSAN, Joseph H. Graziano et al.
Recent evidence suggests that the development of skin lesions from arsenic exposure may be mediated by increases in the expression of various growth factors, including transforming growth factor-alpha (TGFα). To investigate this association in humans, levels of total urinary arsenic and urinary TGFα...
Faruque Parvez, Yu Chen, Mahbub Yunus, M. Argos et al.
ISEE-0781 Background: The dose-response relationship between arsenic (As) exposure and lung disorder is not clear, particularly for exposure at low-to-moderate levels. We conducted a prospective cohort study to evaluate the effect of As exposure on respiratory symptoms in the HEALS cohort in Araihaz...