Quangang Zhu, Zhongjian Chen, Pijush Paul, Yi Lü et al.
Proteins and peptides (PPs) have gradually become more attractive therapeutic molecules than small molecular drugs due to their high selectivity and efficacy, but fewer side effects. Owing to the poor stability and limited permeability through gastrointestinal (GI) tract and epithelia, the therapeut...
Munir Ahmad Khan, Abul Kalam Azad, Muhammad Safdar, Asif Nawaz et al.
This project aims to synthesize and characterize the pH-sensitive controlled release of 5-fluorouracil (5-FU) loaded hydrogels (5-FULH) by polymerization of acrylamide (AM) and acrylic acid (AA) in the presence of glutaraldehyde (GA) as a crosslinker with ammonium persulphate as an initiator. The fo...
Pijush Paul, Titpawan Nakpheng, Himanshu Paliwal, K. Prem Ananth et al.
Delivering novel antimycobacterial agents through the pulmonary route using nanoparticle-based systems shows promise for treating diseases like tuberculosis. However, creating dry powder inhaler (DPI) with suitable aerodynamic characteristics while preserving nanostructure integrity and maintaining ...
Himanshu Paliwal, Titpawan Nakpheng, Pijush Paul, K. Prem Ananth et al.
Tuberculosis (TB) is a serious health issue that contributes to millions of deaths throughout the world and increases the threat of serious pulmonary infections in patients with respiratory illness. Delamanid is a novel drug approved in 2014 to deal with multi-drug resistant TB (MDR-TB). Despite its...
Sardar Mohammad Ashraful Islam, Pijush Paul, Mohammad Shahriar, Irin Dewan et al.
 Abstract: In this study solid dispersions (SDs) of spironolactone were prepared by solvent evaporation technique using poloxomer 407,  kollicoat IR, kollidon VA 64 and PEG 6000 as carrier. The solid dispersions were investigated for drug loading and dissolution behavior. Solid dispersions were fo...
Pijush Paul, Wei Wu, Teerapol Srichana
Macrophages are employed as targets for delivering genes, drugs, or lipid nanoparticles into tumors or other specific sites. Studying the interaction between solid lipid nanoparticles (SLNs) and macrophages is essential for assessing nanotoxicity and advancing the development of nanomedicines. Howev...
Bijon Kumar Sil, Mohd. Raeed Jamiruddin, Md. Ahsanul Haq, Nattanit Aekwattanaphol et al.
•The detection of ascorbic acid is one step using horse radish peroxidase inhibition•The method is very sensitive and reproducible with limit of quantification at 4 nM.•The methodology does not need sample purification. Ascorbic acid plays a significant role in regulation of various bodily functions...
Bijon Kumar Sil, Mohd. Raeed Jamiruddin, Pijush Paul, Nattanit Aekwattanaphol et al.
Serine proteases (SPs) are distributed among all living cells accounting for almost one-third of all proteases. Dysregulation of SPs during inflammation and/or infection can result in devastating consequences, such as skin and lung inflammation, neuroinflammation, arthritis, as well as metastasis of...
Prodip Kumar Biswas, Gopal Saha, Mohammed Shahadat Hossain, Md Nasir Uddin et al.
Aim: The study was undertaken with an objective to know the thyroid functions in Type 2 diabetics and to know the spectrum of thyroid dysfunction in Type 2 DM.
 Methods: The present study included 68OPD and IPD patients of Type 2 DM who attended the Department of General Medicine at Dhaka Medic...
Pijush Paul, Himanshu Paliwal, K. Prem Ananth
Abul Kalam Azad, Pijush Paul, Abdul Majid, Masoud Mozafari