Prawej Ansari, Samara T. Choudhury, Véronique Seidel, Akib Bin Rahman et al.
Diabetes Mellitus (DM) is a metabolic disorder that is spreading alarmingly around the globe. Type-2 DM (T2DM) is characterized by low-grade inflammation and insulin resistance and is closely linked to obesity. T2DM is mainly controlled by lifestyle/dietary changes and oral antidiabetic drugs but re...
Prawej Ansari, Noushin Tabasumma, Nayla Nuren Snigdha, Nawfal Hasan Siam et al.
Diabetes mellitus is one of the most frequently occurring metabolic disorders (DMs), impairing healthy life around the globe, with mild-to-severe secondary complications. DM is associated with secondary complications, including diabetic retinopathy (DR), which damages the retina and can lead to visi...
Prawej Ansari, Samia Akther, J. M. A. Hannan, Véronique Seidel et al.
Diabetes mellitus is a chronic complication that affects people of all ages. The increased prevalence of diabetes worldwide has led to the development of several synthetic drugs to tackle this health problem. Such drugs, although effective as antihyperglycemic agents, are accompanied by various side...
Prawej Ansari, Alexa D. Reberio, Nushrat J. Ansari, Sandeep Kumar et al.
Conditions like diabetes mellitus (DM), cancer, infections, inflammation, cardiovascular diseases (CVDs), and gastrointestinal (GI) disorders continue to have a major global impact on mortality and morbidity. Medicinal plants have been used since ancient times in ethnomedicine (e.g., Ayurveda, Unani...
Sohel Bin Azad, Prawej Ansari, Shofiul Azam, Saad Mosharraf Hossain et al.
Moringa oleifera has potential anti-hyperglycaemic effects that have been reported earlier by different scientific groups using animal models of diabetes. We aimed to explore the possible mechanisms of action of M. oleifera extract through different methods. Primarily, we measured fasting blood gluc...
J. M. A. Hannan, Prawej Ansari, Shofiul Azam, Peter R. Flatt et al.
Spirulina platensis has been found to be useful in the treatment of type 2 diabetes. The present study aims to elucidate the effects of ethanol extract and butanol fraction of S. platensis on insulin release and glucose homoeostasis in type 2 diabetic rats, together with their mechanism of actions. ...
Prawej Ansari, J. Samia, Joyeeta T. Khan, Musfiqur Rahman Rafi et al.
Diabetes mellitus (DM) comprises a range of metabolic disorders characterized by high blood glucose levels caused by defects in insulin release, insulin action, or both. DM is a widespread condition that affects a substantial portion of the global population, causing high morbidity and mortality rat...
Prawej Ansari, Shofiul Azam, J. M. A. Hannan, Peter R. Flatt et al.
ETHNOPHARMACOLOGICAL RELEVANCE Hibiscus rosa-sinensis (HRS) is a tropical flowery plant, widely distributed in Asian region and an important traditional medicine used in many diseases including cough, diarrhoea and diabetes. AIM OF THIS STUDY Hibiscus rosa-sinensis (HRS) leaves have been reported to...
Prawej Ansari, Joyeeta T. Khan, Suraiya Chowdhury, Alexa D. Reberio et al.
Diabetes mellitus (DM) is currently regarded as a global public health crisis for which lifelong treatment with conventional drugs presents limitations in terms of side effects, accessibility, and cost. Type 2 diabetes (T2DM), usually associated with obesity, is characterized by elevated blood gluco...
Prawej Ansari, Md. Josim Uddin, Md. Masudur Rahman, Md. Abdullah-Al-Mamun et al.
BACKGROUND: Persicaria orientalis, an ornamental medicinal plant, has been used in traditional medicine for the treatment of various diseases. Although the plant is reported to have some important pharmacological effects, many medicinal values remain unidentified. Our objective was to evaluate the a...
JMA Hannan, Prawej Ansari, A. K. Enamul Haque, Afrina Sanju et al.
Abstract Nigella sativa seeds are traditionally reputed as possessing anti-diabetic properties. As a result, we aim to explore the mechanism of its anti-hyperglycemic activity. The present study uses various experimental designs including gastrointestinal (GI) motility, intestinal disaccharidase act...
Prawej Ansari, Samia Akther, Joyeeta T. Khan, Sara S. Islam et al.
Diabetes mellitus, a major cause of mortality around the globe, can result in several secondary complications, including diabetic foot syndrome, which is brought on by diabetic neuropathy and ischemia. Approximately 15% of diabetic patients suffer from diabetic foot complications, and among them 25%...
Prawej Ansari, Nadia Afroz, Shahnaz Jalil, Sohel Bin Azad et al.
BACKGROUND: Aegle marmelos (commonly known as Bael, golden apple) was formerly described to have anti-hyperglycemic activity. The present study aimed to explore the possible effects, in depth, of A. marmelos extracts on carbohydrate absorption, glucose utilization, and α-amylase inhibition and insul...
Hamid A. Bakshi, Gerry A. Quinn, Alaa A. A. Aljabali, Faruck Lukmanul Hakkim et al.
The prevalence of colon-associated diseases has increased significantly over the past several decades, as evidenced by accumulated literature on conditions such as Crohn's disease, irritable bowel syndrome, colorectal cancer, and ulcerative colitis. Developing therapeutics for these diseases is chal...
Prawej Ansari, Peter R. Flatt, Patrick Harriott, J. M. A. Hannan et al.
Acacia arabica is used traditionally to treat a variety of ailments, including diabetes. This study elucidated the antidiabetic actions of A. arabica bark together with the isolation of bioactive molecules. Insulin secretion and signal transduction were measured using clonal β cells and mouse islets...